Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nea Korvenlaita"'
Autor:
Sohvi Ohtonen, Luca Giudice, Henna Jäntti, Mohammad Feroze Fazaludeen, Anastasia Shakirzyanova, Mireia Gómez-Budia, Nelli-Noora Välimäki, Jonna Niskanen, Nea Korvenlaita, Ilkka Fagerlund, Jari Koistinaho, Mahmood Amiry-Moghaddam, Ekaterina Savchenko, Laurent Roybon, Šárka Lehtonen, Paula Korhonen, Tarja Malm
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract LRRK2-G2019S is one of the most common Parkinson’s disease (PD)-associated mutations and has been shown to alter microglial functionality. However, the impact of LRRK2-G2019S on transcriptional profile of human induced pluripotent stem cel
Externí odkaz:
https://doaj.org/article/cbf0d639bf06480ebb4d53aab63905d3
Autor:
Flavia Scoyni, Valeriia Sitnikova, Luca Giudice, Paula Korhonen, Davide M. Trevisan, Ana Hernandez de Sande, Mireia Gomez-Budia, Raisa Giniatullina, Irene F. Ugidos, Hiramani Dhungana, Cristiana Pistono, Nea Korvenlaita, Nelli-Noora Välimäki, Salla M. Kangas, Anniina E. Hiltunen, Emma Gribchenko, Minna U. Kaikkonen-Määttä, Jari Koistinaho, Seppo Ylä-Herttuala, Reetta Hinttala, Morten T. Venø, Junyi Su, Markus Stoffel, Anne Schaefer, Nikolaus Rajewsky, Jørgen Kjems, Mary P. LaPierre, Monika Piwecka, Jukka Jolkkonen, Rashid Giniatullin, Thomas B. Hansen, Tarja Malm
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113862- (2024)
Summary: Brain functionality relies on finely tuned regulation of gene expression by networks of non-coding RNAs (ncRNAs) such as the one composed by the circular RNA ciRS-7 (also known as CDR1as), the microRNA miR-7, and the long ncRNA Cyrano. We de
Externí odkaz:
https://doaj.org/article/3f5181ebf602423b89fa5aca16a2796d
Autor:
Henna Jäntti, Valeriia Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Irene F. Ugidos, Mireia Gómez-Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya, Feroze Fazaludeen, Nikita Mikhailov, Maria Gotkiewicz, Kirsi Ketola, Šárka Lehtonen, Jari Koistinaho, Katja M. Kanninen, Damian Hernández, Alice Pébay, Rosalba Giugno, Paula Korhonen, Rashid Giniatullin, Tarja Malm
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-22 (2022)
Abstract Background Microglia are the endogenous immune cells of the brain and act as sensors of pathology to maintain brain homeostasis and eliminate potential threats. In Alzheimer's disease (AD), toxic amyloid beta (Aβ) accumulates in the brain a
Externí odkaz:
https://doaj.org/article/1e1bbd5ec02d41988a4d4b166aeb1c91
Autor:
Nea Korvenlaita, Mireia Gómez‐Budia, Flavia Scoyni, Cristiana Pistono, Luca Giudice, Shaila Eamen, Sanna Loppi, Ana Hernández deSande, Benjamin Huremagic, Maria Bouvy‐Liivrand, Merja Heinäniemi, Minna U. Kaikkonen, Lesley Cheng, Andrew F. Hill, Katja M. Kanninen, Guido W. Jenster, Martin E. vanRoyen, Laura Ramiro, Joan Montaner, Tereza Batkova, Robert Mikulik, Rosalba Giugno, Jukka Jolkkonen, Paula Korhonen, Tarja Malm
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 1, Pp n/a-n/a (2023)
Abstract Hypoxia induces changes in the secretion of extracellular vesicles (EVs) in several non‐neuronal cells and pathological conditions. EVs are packed with biomolecules, such as microRNA(miR)‐21‐5p, which respond to hypoxia. However, the t
Externí odkaz:
https://doaj.org/article/094e282ac7ab43019b81d3777335442b
Autor:
Nea Korvenlaita, Lauri Louhivuori
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3295 (2022)
An increasing amount of evidence points to an important role of macrophages in peripheral nerve injury (PNI) and associated pain. Peripheral nerve macrophages facilitate the regeneration, while dorsal root ganglia (DRG) macrophages might propagate th
Externí odkaz:
https://doaj.org/article/9cea278b1b37449db6c39c1be51e2729
Autor:
Flavia Scoyni, Valeriia Sitnikova, Luca Giudice, Paula Korhonen, Davide M Trevisan, Ana Hernandez de Sande, Mireia Gomez-Budia, Raisa Giniatullina, Irene F Ugidos, Hiramani Dhungana, Cristiana Pistono, Nea Korvenlaita, Nelli-Noora Välimäki, Salla M Kangas, Anniina E Hiltunen, Minna U Kaikkonen-Määttä, Jari Koistinaho, Seppo Ylä-Herttuala, Reetta Hinttala, Morten T Venø, Junyi Su, Markus Stoffel, Anne Schaefer, Nikolaus Rajewsky, Jørgen Kjems, Mary P LaPierre, Monika Piwecka, Jukka Jolkkonen, Rashid Giniatullin, Thomas B Hansen, Malm Tarja
Brain functionality resides on finely tuned regulation of gene expression by networks of non-coding RNAs (ncRNAs) such as the one composed by the circular RNA ciRS-7, the microRNA miR-7 and the long non-coding RNA Cyrano. However, very little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3e1bb4b25620fb6dfa176ceecb3a6d4
https://doi.org/10.1101/2023.01.24.525136
https://doi.org/10.1101/2023.01.24.525136
Autor:
Masoumeh Es-Haghi, Olga Neustroeva, Iftekhar Chowdhury, Pia Laitinen, Mari-Anna Väänänen, Nea Korvenlaita, Tarja Malm, Mikko P. Turunen, Tiia A. Turunen
Publikováno v:
Genes
Volume 14
Issue 2
Pages: 261
Volume 14
Issue 2
Pages: 261
Extracellular vesicles (EVs) naturally carry cargo from producer cells, such as RNA and protein, and can transfer these messengers to other cells and tissue. This ability provides an interesting opportunity for using EVs as delivery vehicles for ther
Autor:
Henna Konttinen, Valeria Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Irene F Ugidos, Mireia Gómez-Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya, Feroze Fazaludeen, Nikita Mikhailov, Maria Gotkiewicz, Kirsi Ketola, Šárka Lehtonen, Jari Koistinaho, Katja M Kanninen, Damian Hernández, Alice Pébay, Rosalba Giugno, Paula Korhonen, Rashid Giniatullin, Tarja Malm
BackgroundMicroglia are the endogenous immune cells of the brain and act as sensors of pathology to maintain brain homeostasis and eliminate potential threats. In Alzheimer’s disease (AD), toxic amyloid beta (Aβ) accumulates in the brain and forms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5900f5eb8f6812162858261f7e8e5635
https://hdl.handle.net/11562/1080768
https://hdl.handle.net/11562/1080768