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Akademický článek
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Autor:
Worley, Beth L., Kim, Yeon Soo, Mardini, Jennifer, Zaman, Rameez, Leon, Kelly E., Vallur, Piyushi Gupta, Nduwumwami, Asvelt, Warrick, Joshua I., Timmins, Patrick F., Kesterson, Joshua P., Phaëton, Rébécca, Lee, Nam Y., Walter, Vonn, Endres, Lauren, Mythreye, Karthikeyan, Aird, Katherine M., Hempel, Nadine
Publikováno v:
In Redox Biology July 2019 25
Autor:
Hengst, Jeremy A.1 (AUTHOR), Nduwumwami, Asvelt J.2 (AUTHOR), Yun, Jong K.1 (AUTHOR) jky1@psu.edu
Publikováno v:
Cancers. Nov2022, Vol. 14 Issue 21, p5182. 23p.
Publikováno v:
Cannabis and cannabinoid research. 7(5)
Background: Endogenous and synthetic cannabinoids have been shown to induce cancer cell death through the accumulation of the sphingolipid, ceramide (Cer). Recently, we have demonstrated that Cer accumulation enhances the induction of immunogenic cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8fdb9893e192ad913564a34921691c
https://pubmed.ncbi.nlm.nih.gov/34846947
https://pubmed.ncbi.nlm.nih.gov/34846947
Autor:
Beth L. Worley, Yeon Soo Kim, Jennifer Mardini, Rameez Zaman, Kelly E. Leon, Piyushi Gupta Vallur, Asvelt Nduwumwami, Joshua I. Warrick, Patrick F. Timmins, Joshua P. Kesterson, Rébécca Phaëton, Nam Y. Lee, Vonn Walter, Lauren Endres, Karthikeyan Mythreye, Katherine M. Aird, Nadine Hempel
Publikováno v:
Redox Biology, Vol 25, Iss , Pp - (2019)
Ovarian cancer remains the most lethal gynecologic malignancy, and is primarily diagnosed at late stage when considerable metastasis has occurred in the peritoneal cavity. At late stage abdominal cavity ascites accumulation provides a tumor-supportin
Externí odkaz:
https://doaj.org/article/0ee39ed6b42940489efa251bb7ae9eb6
Autor:
Ishimwe Cédrick, Tuyisenge Nkusi Ange, Nduwumwami Ivan, Uwiduhaye Fabrice, G. Senthil Kumaran
Publikováno v:
Civil Engineering and Architecture. 9:2278-2285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5237daa017a58eff8cab414c23a91ddc
https://doi.org/10.13189/cea.2021.090715
https://doi.org/10.13189/cea.2021.090715
Publikováno v:
Cancers; Volume 14; Issue 21; Pages: 5182
We recently identified the sphingosine kinases (SphK1/2) as key intracellular regulators of immunogenic cell death (ICD) in colorectal cancer (CRC) cells. To better understand the mechanism by which SphK inhibition enhances ICD, we focused on the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c44a3a06d04854ce7d641e79365169
https://pubmed.ncbi.nlm.nih.gov/36358599
https://pubmed.ncbi.nlm.nih.gov/36358599
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 378:300-310
Agents that induce immunogenic cell death (ICD) alter the cellular localization of calreticulin (CRT) causing it to become cell surface exposed within the plasma membrane lipid raft microdomain (ectoCRT) where it serves as a damage associated molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63e83a3b73ceb41c9dd6fe305f4ec50
https://doi.org/10.1124/jpet.121.000629
https://doi.org/10.1124/jpet.121.000629
We have previously identified sphingolipid metabolism as a key intracellular process associated with immunogenic cell death (ICD) induced by mitoxantrone in colon cancer cells. Specifically, we have demonstrated that inhibition of the sphingosine kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::848be63d5c4dee2acc74fbe1736ada6f
https://doi.org/10.1101/2021.09.16.460650
https://doi.org/10.1101/2021.09.16.460650
Akademický článek
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