Dynamic landscape and regulation of RNA editing in mammals

Autor: Tan, Meng How, Qin, Li, Shanmugam, Raghuvaran, Piskol, Robert, Kohler, Jennefer, Young, Amy N., Liu, Kaiwen Ivy, Zhang, Rui, Ramaswami, Gokul, Ariyoshi, Kentaro, Gupte, Ankita, Keegan, Liam P., George, Cyril X., Ramu, Avinash, Huang, Ni, Pollina, Elizabeth A., Leeman, Dena S., Rustighi, Alessandra, Goh, Y. P. Sharon, Aguet, François, Ardlie, Kristin G., Cummings, Beryl B., Gelfand, Ellen T., Getz, Gad, Hadley, Kane, Handsaker, Robert E., Huang, Katherine H., Kashin, Seva, Karczewski, Konrad J., Lek, Monkol, Xiao, Li, Macarthur, Daniel G., Nedzel, Jared L., Nguyen, Duyen T., Noble, Michael S., Segrè, Ayellet V., Trowbridge, Casandra A., Tukiainen, Taru, Abell, Nathan S., Balliu, Brunilda, Barshir, Ruth, Basha, Omer, Battle, Alexis, Bogu, Gireesh K., Brown, Andrew, Brown, Christopher D., Castel, Stephane E., Chen, Lin S., Chiang, Colby, Conrad, Donald F., Cox, Nancy J., Damani, Farhan N., Davis, Joe R., Delaneau, Olivier, Dermitzakis, Emmanouil T., Engelhardt, Barbara E., Eskin, Eleazar, Ferreira, Pedro G., Frésard, Laure, Gamazon, Eric R., Garrido-Martín, Diego, Gewirtz, Ariel D. H., Gliner, Genna, Gloudemans, Michael J., Guigo, Roderic, Hall, Ira M., Han, Buhm, Yuan, He, Hormozdiari, Farhad, Howald, Cedric, Hae Kyung, Im, Brian, Jo, Kang, Eun Yong, Kim, Yungil, Kim-Hellmuth, Sarah, Lappalainen, Tuuli, Gen, Li, Xin, Li, Liu, Boxiang, Mangul, Serghei, Mccarthy, Mark I., Mcdowell, Ian C., Mohammadi, Pejman, Monlong, Jean, Montgomery, Stephen B., Muñoz-Aguirre, Manuel, Ndungu, Anne W., Nicolae, Dan L., Nobel, Andrew B., Oliva, Meritxell, Ongen, Halit, Palowitch, John J., Panousis, Nikolaos, Papasaikas, Panagiotis, Park, Yoson, Parsana, Princy, Payne, Anthony J., Peterson, Christine B., Quan, Jie, Reverter, Ferran, Sabatti, Chiara, Saha, Ashis, Sammeth, Michael, Scott, Alexandra J., Shabalin, Andrey A., Sodaei, Reza, Stephens, Matthew, Stranger, Barbara E., Strober, Benjamin J., Sul, Jae Hoon, Tsang, Emily K., Urbut, Sarah, Van De Bunt, Martijn, Wang, Gao, Wen, Xiaoquan, Wright, Fred A., Hualin S., Xi, Yeger-Lotem, Esti, Zappala, Zachary, Zaugg, Judith B., Zhou, Yi-Hui, Akey, Joshua M., Bates, Daniel, Chan, Joanne, Claussnitzer, Melina, Demanelis, Kathryn, Diegel, Morgan, Doherty, Jennifer A., Feinberg, Andrew P., Fernando, Marian S., Halow, Jessica, Hansen, Kasper D., Haugen, Eric, Hickey, Peter F., Hou, Lei, Jasmine, Farzana, Jian, Ruiqi, Jiang, Lihua, Johnson, Audra, Kaul, Rajinder, Kellis, Manolis, Kibriya, Muhammad G., Lee, Kristen, Lin, Jessica, Lin, Shin, Linder, Sandra, Linke, Caroline, Liu, Yaping, Maurano, Matthew T., Molinie, Benoit, Nelson, Jemma, Neri, Fidencio J., Park, Yongjin, Pierce, Brandon L., Rinaldi, Nicola J., Rizzardi, Lindsay F., Sandstrom, Richard, Skol, Andrew, Smith, Kevin S., Snyder, Michael P., Stamatoyannopoulos, John, Tang, Hua, Wang, Li, Wang, Meng, Van Wittenberghe, Nicholas, Fan, Wu, Nierras, Concepcion R., Branton, Philip A., Carithers, Latarsha J., Guan, Ping, Moore, Helen M., Rao, Abhi, Vaught, Jimmie B., Gould, Sarah E., Lockart, Nicole C., Martin, Casey, Struewing, Jeffery P., Volpi, Simona, Addington, Anjene M., Koester, Susan E., Little, A. Roger, Brigham, Lori E., Hasz, Richard, Hunter, Marcus, Johns, Christopher, Johnson, Mark, Kopen, Gene, Leinweber, William F., Lonsdale, John T., Mcdonald, Alisa, Mestichelli, Bernadette, Myer, Kevin, Roe, Brian, Salvatore, Michael, Shad, Saboor, Thomas, Jeffrey A., Walters, Gary, Washington, Michael, Wheeler, Joseph, Bridge, Jason, Foster, Barbara A., Gillard, Bryan M., Karasik, Ellen, Kumar, Rachna, Miklos, Mark, Moser, Michael T., Jewell, Scott D., Montroy, Robert G., Rohrer, Daniel C., Valley, Dana R., Davis, David A., Mash, Deborah C., Undale, Anita H., Smith, Anna M., Tabor, David E., Roche, Nancy V., Mclean, Jeffrey A., Vatanian, Negin, Robinson, Karna L., Sobin, Leslie, Barcus, Mary E., Valentino, Kimberly M., Liqun, Qi, Hunter, Steven, Hariharan, Pushpa, Singh, Shilpi, Ki Sung, Um, Matose, Takunda, Tomaszewski, Maria M., Barker, Laura K., Mosavel, Maghboeba, Siminoff, Laura A., Traino, Heather M., Flicek, Paul, Juettemann, Thomas, Ruffier, Magali, Sheppard, Dan, Taylor, Kieron, Trevanion, Stephen J., Zerbino, Daniel R., Craft, Brian, Goldman, Mary, Haeussler, Maximilian, Kent, W. James, Lee, Christopher M., Paten, Benedict, Rosenbloom, Kate R., Vivian, John, Zhu, Jingchun, Chawla, Ajay, Del Sal, Giannino, Peltz, Gary, Brunet, Anne, Samuel, Charles E., O'Connell, Mary A., Walkley, Carl R., Nishikura, Kazuko, Jin Billy, Li

Publikováno v: Nature, Vol. 550, No 7675 (2017) pp. 249-254

Adenosine-to-inosine (A-to-I) RNA editing is a conserved post-transcriptional mechanism mediated by ADAR enzymes that diversifies the transcriptome by altering selected nucleotides in RNA molecules1. Although many editing sites have recently been dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49498ad61e56b505867bb3f95eb17e18
https://acuresearchbank.acu.edu.au/item/86wyy/dynamic-landscape-and-regulation-of-rna-editing-in-mammals

Risk of pneumococcal bacteremia in Kenyan children with glucose-6-phosphate dehydrogenase deficiency.

Autor: Gilchrist, James J., Uyoga, Sophie, Pirinen, Matti, Rautanen, Anna, Mwarumba, Salim, Njuguna, Patricia, Mturi, Neema, The Kenyan Bacteraemia Study Group, Hill, Adrian V. S., Williams, Thomas N., Scott, J. Anthony G., Chapman, Stephen J., Mills, Tara C., Rockett, Kirk, Ndungu, Anne W., Naranbhai, Vivek, Macharia, Alex W., Ndila, Carolyne, Mohammed, Shebe, Berkley, James A.

Publikováno v: BMC Medicine; 6/15/2020, Vol. 18 Issue 1, p1-10, 10p, 1 Chart, 2 Graphs

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Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children

Autor: Rautanen, Anna, Pirinen, Matti, Mills, Tara C., Rockett, Kirk A., Strange, Amy, Ndungu, Anne W., Naranbhai, Vivek, Gilchrist, James J., Bellenguez, Céline, Freeman, Colin, Band, Gavin, Bumpstead, Suzannah J., Edkins, Sarah, Giannoulatou, Eleni, Gray, Emma, Dronov, Serge, Hunt, Sarah E., Langford, Cordelia, Pearson, Richard D., Su, Zhan, Vukcevic, Damjan, Macharia, Alex W., Uyoga, Sophie, Ndila, Carolyne, Mturi, Neema, Njuguna, Patricia, Mohammed, Shebe, Berkley, James A., Mwangi, Isaiah, Mwarumba, Salim, Kitsao, Barnes S., Lowe, Brett S., Morpeth, Susan C., Khandwalla, Iqbal, Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N.A., Plomin, Robert, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Deloukas, Panos, Peltonen, Leena, Williams, Thomas N., Scott, J. Anthony G., Chapman, Stephen J., Donnelly, Peter, Hill, Adrian V.S., Spencer, Chris C.A.

Publikováno v: Rautanen, A, Pirinen, M, Mills, TC, Rockett, KA, Strange, A, Ndungu, AW, Naranbhai, V, Gilchrist, JJ, Bellenguez, C, Freeman, C, Band, G, Bumpstead, SJ, Edkins, S, Giannoulatou, E, Gray, E, Dronov, S, Hunt, SE, Langford, C, Pearson, RD, Su, Z, Vukcevic, D, Macharia, AW, Uyoga, S, Ndila, C, Mturi, N, Njuguna, P, Mohammed, S, Berkley, JA, Mwangi, I, Mwarumba, S, Kitsao, BS, Lowe, BS, Morpeth, SC, Khandwalla, I, Blackwell, JM, Bramon, E, Brown, MA, Casas, JP, Corvin, A, Duncanson, A, Jankowski, J, Markus, HS, Mathew, CG, Palmer, CN A, Plomin, R, Sawcer, SJ, Trembath, RC, Viswanathan, AC, Wood, NW, Deloukas, P, Peltonen, L, Williams, TN, Scott, J AG, Chapman, SJ, Donnelly, P, Hill, AV S & Spencer, CC A 2016, ' Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children ', American Journal of Human Genetics, vol. 98, no. 6, pp. 1092-1100 . https://doi.org/10.1016/j.ajhg.2016.03.025

Bacteremia (bacterial bloodstream infection) is a major cause of illness and death in sub-Saharan Africa but little is known about the role of human genetics in susceptibility. We conducted a genome-wide association study of bacteremia susceptibility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8fe9ab9dee5c4c0e2e0d657971b691a9