Genomic epidemiology of Escherichia coli: antimicrobial resistance through a One Health lens in sympatric humans, livestock and peri-domestic wildlife in Nairobi, Kenya

Autor: Dishon M. Muloi, James M. Hassell, Bryan A. Wee, Melissa J. Ward, Judy M. Bettridge, Velma Kivali, Alice Kiyong’a, Christine Ndinda, Nduhiu Gitahi, Tom Ouko, Titus Imboma, James Akoko, Maurice K. Murungi, Samuel M. Njoroge, Patrick Muinde, Lorren Alumasa, Titus Kaitho, Fredrick Amanya, Allan Ogendo, Bram A. D. van Bunnik, John Kiiru, Timothy P. Robinson, Erastus K. Kang’ethe, Samuel Kariuki, Amy B. Pedersen, Eric M. Fèvre, Mark E. J. Woolhouse

Publikováno v: BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)

Abstract Background Livestock systems have been proposed as a reservoir for antimicrobial-resistant (AMR) bacteria and AMR genetic determinants that may infect or colonise humans, yet quantitative evidence regarding their epidemiological role remains

Externí odkaz: https://doaj.org/article/231247c947044a77a26ac7e53c9d3e9a

Molecular Prevalence and Risk Factors of Campylobacter Infection in Puppies in the Nairobi Metropolitan Region, Kenya

Autor: Sharon N. Mbindyo, Jafred M. A. Kitaa, Tequiero O. Abuom, Gabriel O. Aboge, Daniel W. Muasya, Beatrice W. Muchira, Nduhiu Gitahi, Charles M. Mulei

Publikováno v: Veterinary Medicine International, Vol 2023 (2023)

Campylobacter species are widely distributed pathogens; however, data on its epidemiology in puppies remain scanty, especially in Kenya. A cross-sectional study was conducted in the Nairobi Metropolitan Region to determine molecular prevalence and as

Externí odkaz: https://doaj.org/article/a39968fb3bec49bc9dd3de9d25ee869a

Prevalence and risk factors for exposure to Toxoplasma gondii in slaughterhouse workers in western Kenya

Autor: Elizabeth Anne Jessie Cook, Nduhiu Gitahi, William Anson de Glanville, Lian F. Thomas, Samuel Kariuki, Erastus Kang’ethe, Eric Maurice Fèvre

Publikováno v: BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-8 (2021)

Abstract Background Toxoplasma gondii is a zoonotic protozoan parasite infecting warm-blooded animals. Infection in people can occur through ingestion of oocysts passed in the faeces of the definitive hosts; ingestion of bradyzoites in the tissue of

Externí odkaz: https://doaj.org/article/e92e79f9412b4499af1a276e2ed43ae0

Investigation of extramammary sources of Group B Streptococcus reveals its unusual ecology and epidemiology in camels.

Autor: Dinah Seligsohn, Chiara Crestani, Nduhiu Gitahi, Emelie Lejon Flodin, Erika Chenais, Ruth N Zadoks

Publikováno v: PLoS ONE, Vol 16, Iss 12, p e0252973 (2021)

Camels are vital to food production in the drylands of the Horn of Africa, with milk as their main contribution to food security. A major constraint to camel milk production is mastitis, inflammation of the mammary gland. The condition negatively imp

Externí odkaz: https://doaj.org/article/0847396d57cb496797c5c4aa9fdb3404

Population genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban landscape

Autor: Dishon M. Muloi, Bryan A. Wee, Deirdre M. H. McClean, Melissa J. Ward, Louise Pankhurst, Hang Phan, Alasdair C. Ivens, Velma Kivali, Alice Kiyong’a, Christine Ndinda, Nduhiu Gitahi, Tom Ouko, James M. Hassell, Titus Imboma, James Akoko, Maurice K. Murungi, Samuel M. Njoroge, Patrick Muinde, Yukiko Nakamura, Lorren Alumasa, Erin Furmaga, Titus Kaitho, Elin M. Öhgren, Fredrick Amanya, Allan Ogendo, Daniel J. Wilson, Judy M. Bettridge, John Kiiru, Catherine Kyobutungi, Cecila Tacoli, Erastus K. Kang’ethe, Julio D. Davila, Samuel Kariuki, Timothy P. Robinson, Jonathan Rushton, Mark E. J. Woolhouse, Eric M. Fèvre

Publikováno v: Muloi, D, Wee, B A, Mcclean, D, Ward, M, Pankhurst, L, Phan, H, Ivens, A, Kivali, V, Kiyonga, A, Ndinda, C, Gitahi, N, Ouko, T, Hassell, J M, Imboma, T, Akoko, J, Murungi, M K, Njoroge, S M, Muinde, P, Nakamura, Y, Alumasa, L, Furmaga, E, Kaitho, T, Öhgren, E, Amanya, F, Ogendo, A, Wilson, D, Bettridge, J, Kiiru, J, Kyobutungi, C, Tacoli, C, Kang'ethe, E, Davila, J, Kariuki, S, Robinson, T, Rushton, J, Woolhouse, M & Fèvre, E M 2022, ' Population genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban landscape ', Nature Microbiology, vol. 7, no. 4, pp. 581-589 . https://doi.org/10.1038/s41564-022-01079-y
Nature Microbiology

Quantitative evidence for the risk of zoonoses and the spread of antimicrobial resistance remains lacking. Here, as part of the UrbanZoo project, we sampled Escherichia coli from humans, livestock and peri-domestic wildlife in 99 households across Na

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adfb936122e3471f472e2a216196868
https://hdl.handle.net/20.500.11820/c3bb9655-0759-434b-84f1-275396abb1e8