Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ndongala Michel Lubaki"'
Autor:
Dongfang Liu, Shuo Tian, Kai Zhang, Wei Xiong, Ndongala Michel Lubaki, Zhiying Chen, Weidong Han
Publikováno v:
Protein & Cell, Vol 8, Iss 12, Pp 861-877 (2017)
ABSTRACT Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells contribute to the body’s immune defenses. Current chimeric antigen receptor (CAR)-modified T cell immunotherapy shows strong promise for treating various cancers and infectious d
Externí odkaz:
https://doaj.org/article/688bcc755d364c3595fce228e7280c76
Autor:
Patrick Younan, Mathieu Iampietro, Andrew Nishida, Palaniappan Ramanathan, Rodrigo I. Santos, Mukta Dutta, Ndongala Michel Lubaki, Richard A. Koup, Michael G. Katze, Alexander Bukreyev
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT Ebola virus (EBOV) disease (EVD) results from an exacerbated immunological response that is highlighted by a burst in the production of inflammatory mediators known as a “cytokine storm.” Previous reports have suggested that nonspecific
Externí odkaz:
https://doaj.org/article/48b879ffa3974e9c88d3f79502e915e8
Autor:
Mathieu Iampietro, Patrick Younan, Andrew Nishida, Mukta Dutta, Ndongala Michel Lubaki, Rodrigo I Santos, Richard A Koup, Michael G Katze, Alexander Bukreyev
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006397 (2017)
Fatal outcomes of Ebola virus (EBOV) infections are typically preceded by a 'sepsis-like' syndrome and lymphopenia despite T cells being resistant to Ebola infection. The mechanisms that lead to T lymphocytes death remain largely unknown; however, th
Externí odkaz:
https://doaj.org/article/aa49fa55904441469156986efb7c5c23
Autor:
Ndongala Michel Lubaki, Patrick Younan, Rodrigo I Santos, Michelle Meyer, Mathieu Iampietro, Richard A Koup, Alexander Bukreyev
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006031 (2016)
Ebola virus (EBOV) infections are characterized by deficient T-lymphocyte responses, T-lymphocyte apoptosis and lymphopenia. We previously showed that disabling of interferon-inhibiting domains (IIDs) in the VP24 and VP35 proteins effectively unblock
Externí odkaz:
https://doaj.org/article/d4c27c0bf52446c099d7d3213b484f09
Autor:
Dongfang Liu, Shuo Tian, Kai Zhang, Wei Xiong, Ndongala Michel Lubaki, Zhiying Chen, Weidong Han
Publikováno v:
Protein & Cell, Vol 9, Iss 10, Pp 902-902 (2017)
Externí odkaz:
https://doaj.org/article/831f109833f64dd58903709d803a0735
Publikováno v:
The Journal of Infectious Diseases. 218:S327-S334
A better understanding of the mechanisms used by Ebola virus to disable the host immune system and spread the infection are of great importance for development of new therapeutic strategies. We demonstrate that treatment of monocytic cells with Ebola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86815d60b4cffc52e0ea97158a93dd74
https://doi.org/10.1093/infdis/jiy406
https://doi.org/10.1093/infdis/jiy406
Autor:
Wei Xiong, Zhiying Chen, Kai Zhang, Shuo Tian, Weidong Han, Ndongala Michel Lubaki, Dongfang Liu
Publikováno v:
Protein & Cell, Vol 8, Iss 12, Pp 861-877 (2017)
Protein & Cell
Protein & Cell
Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells contribute to the body’s immune defenses. Current chimeric antigen receptor (CAR)-modified T cell immunotherapy shows strong promise for treating various cancers and infectious diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301a8fa3bc84439b1be615180529e5d2
http://link.springer.com/article/10.1007/s13238-017-0415-5
http://link.springer.com/article/10.1007/s13238-017-0415-5
Autor:
Palaniappan Ramanathan, Natalia Kuzmina, Patrick Younan, Ndongala Michel Lubaki, Rodrigo I. Santos, Alexander Bukreyev, Andrew I. Flyak, Kai Huang, Pavlo Gilchuk, Philipp A. Ilinykh, James E. Crowe
Publikováno v:
Cell Reports, Vol 24, Iss 7, Pp 1802-1815.e5 (2018)
Summary: Some monoclonal antibodies (mAbs) recovered from survivors of filovirus infections can protect against infection. It is currently unknown whether natural infection also induces some antibodies with the capacity for antibody-dependent enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f6e1a44579358e4f22a1dc7c31167c
https://resolver.caltech.edu/CaltechAUTHORS:20180829-103048502
https://resolver.caltech.edu/CaltechAUTHORS:20180829-103048502
Autor:
Philipp A. Ilinykh, Thomas G. Wood, Alexander Bukreyev, Steven G. Widen, Ndongala Michel Lubaki, Terence C. Theisen, Lynnsey A. Renn, Ronald L. Rabin
Publikováno v:
Journal of Virology. 89:7567-7583
Ebola virus (EBOV) causes a severe hemorrhagic fever with a deficient immune response, lymphopenia, and lymphocyte apoptosis. Dendritic cells (DC), which trigger the adaptive response, do not mature despite EBOV infection. We recently demonstrated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6381d861e6c277752ece58b35476d8
https://doi.org/10.1128/jvi.00924-15
https://doi.org/10.1128/jvi.00924-15
Autor:
Richard A. Koup, Patrick Younan, Mathieu Iampietro, Andrew Nishida, Mukta Dutta, Ndongala Michel Lubaki, Michael G. Katze, Rodrigo I. Santos, Alexander Bukreyev
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006397 (2017)
PLoS Pathogens
PLoS Pathogens
Fatal outcomes of Ebola virus (EBOV) infections are typically preceded by a ‘sepsis-like’ syndrome and lymphopenia despite T cells being resistant to Ebola infection. The mechanisms that lead to T lymphocytes death remain largely unknown; however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f3d14cbdea5736c17f0a128618f5b6
http://europepmc.org/articles/PMC5456411?pdf=render
http://europepmc.org/articles/PMC5456411?pdf=render