Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ndna, nuclear DNA"'
Autor:
Danielle G. Passos-Silva, Elizângela Almeida Rocha, Dawidson Assis Gomes, Joao P. Vieira-da-Rocha, Richard McCulloch, Carlos Renato Machado, Isabela Cecília Mendes
Publikováno v:
DNA Repair
Highlights • DNA repair kinetics evaluated in T. brucei nuclear and mitochondrial genomes. • Higher efficiency of DNA repair in T. brucei cells from the mammal than the tsetse. • Differing cell cycle and survival responses to DNA damage in two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865a1261c26a5c5116370ba7eff05f6e
https://doi.org/10.1016/j.dnarep.2018.11.005
https://doi.org/10.1016/j.dnarep.2018.11.005
Publikováno v:
The Journal of Biological Chemistry
Nucleoside reverse transcriptase inhibitors (NRTIs) were the first drugs used to treat human immunodeficiency virus infection, and their use can cause mitochondrial toxicity, including mitochondrial DNA (mtDNA) depletion in several cases. The first-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc3b5c3b353a26b3f7cfc59dc03a98c
http://europepmc.org/articles/PMC7948951
http://europepmc.org/articles/PMC7948951
Autor:
Anna Karlsson, Ramon Martí, Xiaoshan Zhou, Ferran Vila-Julià, David Molina-Granada, Javier Torres-Torronteras, Yolanda Cámara, Daniel Jiménez-Heis, Cora Blázquez-Bermejo
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
EBioMedicine
Scientia
Universitat Autònoma de Barcelona
EBioMedicine
Scientia
Deoxycytidine; Deoxynucleoside therapy; Encephalomyopathy Desoxicitidina; Terapia basada en desoxinucleósido; Encefalomiopatía Desoxicitidina; Teràpia basada en desoxinucleòsid; Encefalomiopatia BACKGROUND: Thymidine kinase 2 (TK2) catalyses the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d9c527846a421620e33a8e62ea56f2
https://ddd.uab.cat/record/226556
https://ddd.uab.cat/record/226556
Autor:
Florian Brinkert, Holger Prokisch, René Santer, Maja Hempel, Lara M. Marten, Desiree E.C. Smith
Publikováno v:
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 25, Iss, Pp 100681-(2020)
Molecular Genetics and Metabolism Reports, Vol 25, Iss, Pp 100681-(2020)
AARS1 deficiency belongs to the group of disorders affecting aminoacyl-tRNA synthetases. To date, AARS1 deficiency has only been linked to neurologic disorders. We report a 6-year-old girl with microcephaly and developmental delay who presented with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70f36ce546cf94cae57162da9a4c7cc
http://europepmc.org/articles/PMC7691605
http://europepmc.org/articles/PMC7691605
Autor:
Dayan Sun, Hong-Xiang Zheng, Liuyiqi Jiang, Yang Wei, Zhenmin Niu, Fei Wu, Jiucun Wang, Jin Li, Tian-Quan Han
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1211-1226.e15 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1211-1226.e15 (2021)
Background and aims Gallstone disease (cholelithiasis) is a cholesterol-related metabolic disorders with strong familial predisposition. Mitochondrial DNA (mtDNA) variants accumulated during human evolution are associated with some metabolic disorder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd66038e0aec91610204cff78d47bed9
https://pubmed.ncbi.nlm.nih.gov/33279689
https://pubmed.ncbi.nlm.nih.gov/33279689
Publikováno v:
Chinese Journal of Traumatology
Chinese Journal of Traumatology, Vol 25, Iss 1, Pp 1-10 (2022)
Chinese Journal of Traumatology, Vol 25, Iss 1, Pp 1-10 (2022)
Sepsis is a life-threatening clinical syndrome and one of the most challenging health problems in the world. Pathologically, sepsis and septic shock are caused by a dysregulated host immune response to infection, which can eventually lead to multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f78f03c1ea030072286a73467e72f2
https://pubmed.ncbi.nlm.nih.gov/34334261
https://pubmed.ncbi.nlm.nih.gov/34334261
Autor:
Dong Seop Kang, Sang Jun Park, Joo Young Lee, Kang Moo Huh, Han Chang Kang, Yeon Su Choi, Min Suk Shim, Gantumur Battogtokh, Hye Suk Lee, Yong-Yeon Cho
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 8, Iss 6, Pp 862-880 (2018)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Mitochondrial targeting is a promising approach for solving current issues in clinical application of chemotherapy and diagnosis of several disorders. Here, we discuss direct conjugation of mitochondrial-targeting moieties to anticancer drugs, antiox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e4ca6cbbf78d2cfe5750be73f51ab1
http://www.sciencedirect.com/science/article/pii/S2211383518300583
http://www.sciencedirect.com/science/article/pii/S2211383518300583
Autor:
Kazuo Tomita, Akihiro Kurimasa, Manabu Fukumoto, Tomoaki Sato, Taisuke Nagasawa, Yoshikazu Kuwahara, Yuko Takashi, Yoshihiro Nishitani, Hideki Nabika, Kento Igarashi
Publikováno v:
Data in Brief
Data in Brief, Vol 20, Iss, Pp 402-410 (2018)
Data in Brief, Vol 20, Iss, Pp 402-410 (2018)
We present data about mitochondrial DNA (mtDNA) copy number and aquaporin (AQP) gene expression in clinically radioresistant (CRR), ρ0, and their parental cells from human cervical cancer and human tongue squamous cell carcinoma. In both ρ0 and CRR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c710aed54ab987338c246109a5973a48
https://doi.org/10.1016/j.dib.2018.08.025
https://doi.org/10.1016/j.dib.2018.08.025
Autor:
John A. Foekens, A. van de Stolpe, Rolf H. A. M. Vossen, John W.M. Martens, E. C. Timmermans, Seyed Yahya Anvar, Marjolein J.A. Weerts, Stefan Sleijfer
Publikováno v:
Neoplasia, 20(7), 687-696. Neoplasia Press
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 7, Pp 687-696 (2018)
Neoplasia, 20(7), 687-696
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 7, Pp 687-696 (2018)
Neoplasia, 20(7), 687-696
The use of blood-circulating cell-free DNA (cfDNA) as a “liquid biopsy” in oncology is being explored for its potential as a cancer biomarker. Mitochondria contain their own circular genomic entity (mitochondrial DNA, mtDNA), up to even thousands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238fde75cbbae91806dd1f5c9188c624
https://hdl.handle.net/1765/107117
https://hdl.handle.net/1765/107117
Autor:
Jeffrey A. Medin, Teruyuki Yanagisawa, Ryosuke Nomura, Shigeki Kushimoto, Takeya Sato, Yuka Sato
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 407-417 (2017)
Redox Biology
Redox Biology
Highly active anti-retrovirus therapy (HAART) has been used to block the progression and symptoms of human immunodeficiency virus infection. Although it decreases morbidity and mortality, clinical use of HAART has also been linked to various adverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199ff92ea316bbfc7f473293f4473e56
https://doi.org/10.1016/j.redox.2017.06.011
https://doi.org/10.1016/j.redox.2017.06.011