Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ndila, Cm"'
Autor:
Band, G, Leffler, EM, Jallow, M, Sisay-Joof, F, Ndila, CM, Macharia, AW, Hubbart, C, Jeffreys, AE, Rowlands, K, Nguyen, T, Gonçalves, S, Ariani, CV, Stalker, J, Pearson, RD, Amato, R, Drury, E, Sirugo, G, d'Alessandro, U, Bojang, KA, Marsh, K, Peshu, N, Saelens, JW, Diakité, M, Taylor, SM, Conway, DJ, Rockett, KA, Kwiatkowski, DP, Williams, TN
Publikováno v:
Nature. 602:106-111
Host genetic factors can confer resistance against malaria1, raising the question of whether this has led to evolutionary adaptation of parasite populations. Here we searched for association between candidate host and parasite genetic variants in 3,3
Autor:
Gilchrist, JJ, Kariuki, SN, Watson, JA, Band, G, Uyoga, S, Ndila, CM, Mturi, N, Mwarumba, S, Mohammed, S, Mosobo, M, Alasoo, K, Rockett, KA, Mentzer, AJ, Kwiatkowski, DP, Hill, AVS, Maitland, K, Scott, JAG, Williams, TN
Invasive bacterial disease is a major cause of morbidity and mortality in African children. Despite being caused by diverse pathogens, children with sepsis are clinically indistinguishable from one another. In spite of this, most genetic susceptibili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12a6766bb51b546c99f298525a25403
http://hdl.handle.net/10044/1/98502
http://hdl.handle.net/10044/1/98502
Autor:
Ndila, CM, Nyirongo, V, Macharia, AW, Jeffreys, AE, Rowlands, K, Hubbart, C, Busby, GBJ, Band, G, Harding, RM, Rockett, KA, Williams, TN, MalariaGEN Consortium
Publikováno v:
Wellcome Open Research, Vol 5 (2021)
Background: The -α 3.7I-thalassaemia deletion is very common throughout Africa because it protects against malaria. When undertaking studies to investigate human genetic adaptations to malaria or other diseases, it is important to account for any co
Autor:
Ndila, CM, Nyirongo, V, Macharia, AW, Jeffreys, AE, Rowlands, K, Hubbart, C, Busby, GBJ, Band, G, Harding, RM, Rockett, KA, Williams, TN
Background: The -α3.7I-thalassaemia deletion is very common throughout Africa because it protects against malaria. When undertaking studies to investigate human genetic adaptations to malaria or other diseases, it is important to account for any con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::9e048044c2dbc549c88a877f1b18b9bb
http://hdl.handle.net/10044/1/104846
http://hdl.handle.net/10044/1/104846
Autor:
Uyoga, S, Macharia, AW, Mochamah, G, Ndila, CM, Nyutu, G, Makale, J, Tendwa, M, Nyatichi, E, Ojal, J, Otiende, M, Shebe, M, Awuondo, KO, Mturi, N, Peshu, N, Tsofa, B, Maitland, K, Scott, JAG, Williams, T
Background Sickle cell disease (SCD) is the commonest severe monogenic disorder of humans. In Africa, 50-90% of children born with SCD die before they reach their fifth birthday. Through the current study, we aimed to describe the comparative inciden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::491aab4c17102a5b3b3e1058df1c4aa9
http://hdl.handle.net/10044/1/71766
http://hdl.handle.net/10044/1/71766
Autor:
Opi, DH, Swann, O, Macharia, A, Uyoga, S, Band, G, Ndila, CM, Harrison, EM, Thera, MA, Kone, AK, Diallo, DA, Doumbo, OK, Lyke, KE, Plowe, CV, Moulds, JM, Shebbe, M, Mturi, N, Peshu, N, Maitland, K, Raza, A, Kwiatkowski, DP, Rockett, KA, Williams, TN, Rowe, JA
Malaria has been a major driving force in the evolution of the human genome. In sub-Saharan African populations, two neighbouring polymorphisms in the Complement Receptor One (CR1) gene, named Sl2 and McCb, occur at high frequencies, consistent with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::a41375001e172717aac59f2a59b40702
http://hdl.handle.net/10044/1/60676
http://hdl.handle.net/10044/1/60676
Autor:
Macharia, AW, Mochamah, G, Uyoga, S, Ndila, CM, Nyutu, G, Makale, J, Tendwa, M, Nyatichi, E, Ojal, J, Shebe, M, Awuondo, KO, Mturi, N, Peshu, N, Tsofa, B, Scott, JAG, Maitland, K, Williams, TN
Sickle cell anemia (SCA) is the commonest severe monogenic disorders of humans. The disease has been highly characterized in high-income countries but not in sub-Saharan Africa where SCA is most prevalent. We conducted a retrospective cohort study of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9464d6b5bcb32228a37bc3a4967a56bb
https://ora.ox.ac.uk/objects/uuid:f28d0074-f722-48e0-a63c-a49f2ae452aa
https://ora.ox.ac.uk/objects/uuid:f28d0074-f722-48e0-a63c-a49f2ae452aa
Autor:
Malaria Genomic Epidemiology Network, Achidi, Ea, Agbenyega, T, Allen, S, Amodu, O, Bojang, K, Conway, D, Corran, P, Deloukas, P, Djimde, A, Dolo, A, Doumbo, O, Drakeley, C, Duffy, P, Dunstan, S, Evans, J, Farrar, J, Fernando, D, Tran, Th, Horstmann, R, Ibrahim, M, Karunaweera, N, Kokwaro, G, Koram, K, Kwiatkowski, D, Lemnge, M, Makani, J, Marsh, K, Michon, P, Modiano, D, Molyneux, Me, Mueller, I, Mutabingwa, T, Parker, M, Peshu, N, Plowe, C, Puijalon, O, Ragoussis, J, Reeder, J, Reyburn, H, Riley, E, Rogers, J, Sakuntabhai, A, Singhasivanon, P, Sirima, S, Sirugo, G, Tall, A, Taylor, T, Thera, M, Troye Blomberg, M, Williams, T, Wilson, M, Amenga Etego, L, Apinjoh, To, Bougouma, E, Dewasurendra, R, Diakite, M, Enimil, A, Hussein, A, Ishengoma, D, Jallow, M, Lin, E, Ly, A, Mangano, Valentina, Manjurano, A, Manning, L, Ndila, Cm, Nyirongo, V, Oluoch, T, Nguyen, Tn, Suriyaphol, P, Toure, O, Rockett, Ka, Vanderwal, A, Clark, T, Wrigley, R, Alcock, D, Auburn, S, Barnwell, D, Bull, S, Campino, S, Devries, J, Elzein, A, Fitzpatrick, K, Ghansah, A, Green, A, Hart, L, Hilton, E, Hubbart, C, Hughes, C, Jeffreys, Ae, Kivinen, K, Macinnis, B, Manske, M, Maslen, G, Mccreight, M, Mendy, A, Moyes, C, Nyika, A, Potter, C, Risley, P, Rowlands, K, Sanjoaquin, M, Small, K, Somaskantharajah, E, Stevens, M, Teo, Y, Watson, R, Carucci, D, Cook, K, Doyle, A, Duombo, O, Gottlieb, M, Kwiatkowski, D.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::579f926d04a95a0a03afd3a6a4778d3c
http://hdl.handle.net/11573/417911
http://hdl.handle.net/11573/417911
Autor:
Angeliki Kerasidou, J O'Brien, Aaron Vanderwal, Christina Hubbart, Alistair Miles, Catherine L. Moyes, A Nyika, Abier Elzein, J Shelton, Spencer Cca., Anthony Enimil, A Diss, C Hughes, Lucas Amenga-Etego, E Somaskantharajah, Ogobara K. Doumbo, Jacob Almagro Garcia, Valentina D. Mangano, E Drury, Edith Bougama, Angie Green, Busby Gbj., Geraldine M. Clarke, Dominic P. Kwiatkowski, Jiannis Ragoussis, Alphaxard Manjurano, Bronwyn MacInnis, Tobias O. Apinjoh, D Mead, Gareth Maslen, George B.J. Busby, Kirk A. Rockett, Dushyanth Jyothi, C Potter, C Malangone, Muminatou Jallow, I Ragoussis, Ellen M. Leffler, J Rogers, J Stalker, Quang Si Le, J Rodford, D Barnwell, Alieu Mendy, J deVries, Anna E. Jeffreys, Carolyne M. Ndila, E Hilton, Vysaul Nyirongo
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2016, 5, pp.e15266. ⟨10.7554/eLife.15266⟩
Riley, E 2016, ' Admixture into and within sub-Saharan Africa ', eLIFE, vol. 5 . https://doi.org/10.7554/eLife.15266
eLife, Vol 5 (2016)
eLife, eLife Sciences Publication, 2016, 5, pp.e15266. ⟨10.7554/eLife.15266⟩
Riley, E 2016, ' Admixture into and within sub-Saharan Africa ', eLIFE, vol. 5 . https://doi.org/10.7554/eLife.15266
eLife, Vol 5 (2016)
Similarity between two individuals in the combination of genetic markers along their chromosomes indicates shared ancestry and can be used to identify historical connections between different population groups due to admixture. We use a genome-wide,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf3967a3144c48294b9e09a091debf7
https://ora.ox.ac.uk/objects/uuid:33f58c0d-85d7-477f-89f2-0413ba356e0d
https://ora.ox.ac.uk/objects/uuid:33f58c0d-85d7-477f-89f2-0413ba356e0d