Beyond basic characterization and omics: Immunomodulatory roles of platelet-derived extracellular vesicles unveiled by functional testing.

Autor: Palviainen M; EV Group, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, and CURED, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.; EV Core, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland., Puutio J; EV Group, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, and CURED, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Østergaard RH; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Eble JA; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany., Maaninka K; EV Group, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, and CURED, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Butt U; EV Group, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, and CURED, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Ndika J; Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Kari OK; Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Kamali-Moghaddam M; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Kjaer-Sorensen K; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Oxvig C; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Aransay AM; Genome Analysis Platform, Center for Cooperative Research in Biosciences, Basque Research and Technology Alliance (BRTA), Mendaro, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas Y Digestivas (CIBERehd), Madrid, Spain., Falcon-Perez JM; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas Y Digestivas (CIBERehd), Madrid, Spain.; Exosomes Laboratory and Metabolomics Platform, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain.; Ikerbasque, Basque Foundation for Science, Bilbao, Spain., Federico A; Finnish Hub for Development and Validation of Integrated Approaches (FHAIVE); Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Greco D; Finnish Hub for Development and Validation of Integrated Approaches (FHAIVE); Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Laitinen S; Research and Development, Finnish Red Cross Blood Service (FRCBS), Helsinki, Finland., Hayashi Y; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, Denmark., Siljander PR; EV Group, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, and CURED, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.; EV Core, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.

Publikováno v: Journal of extracellular vesicles [J Extracell Vesicles] 2024 Oct; Vol. 13 (10), pp. e12513.

Systemic gene signature of inhaled corticosteroid treatment in allergic asthma to flour.

Autor: Ndika J; Faculty of Medicine, Human Microbiome Research Program, University of Helsinki, Helsinki, Finland., Suojalehto H; Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland., Lindström I; Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland., Airaksinen L; Occupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland., Wisgrill L; Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria., Alenius H; Faculty of Medicine, Human Microbiome Research Program, University of Helsinki, Helsinki, Finland.; Institute of Environmental Medicine (IMM), Karolinska Institutet, Stockholm, Sweden., Karisola P; Faculty of Medicine, Human Microbiome Research Program, University of Helsinki, Helsinki, Finland.

Publikováno v: Allergy [Allergy] 2023 Feb; Vol. 78 (2), pp. 592-595. Date of Electronic Publication: 2022 Dec 07.

Bet v 1 triggers antiviral-type immune signalling in birch-pollen-allergic individuals.

Autor: Wisgrill L; Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Fyhrquist N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Human microbiome research program (HUMI), Medicum, University of Helsinki, Helsinki, Finland., Ndika J; Human microbiome research program (HUMI), Medicum, University of Helsinki, Helsinki, Finland., Paalanen L; National Institute for Health and Welfare, Helsinki, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Berger A; Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria., Laatikainen T; National Institute for Health and Welfare, Helsinki, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Karisola P; Human microbiome research program (HUMI), Medicum, University of Helsinki, Helsinki, Finland., Haahtela T; Skin and Allergy Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Alenius H; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Human microbiome research program (HUMI), Medicum, University of Helsinki, Helsinki, Finland.

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2022 Aug; Vol. 52 (8), pp. 929-941. Date of Electronic Publication: 2022 Feb 18.

Epigenetic Differences in Long Non-coding RNA Expression in Finnish and Russian Karelia Teenagers With Contrasting Risk of Allergy and Asthma.

Autor: Ndika J; Human Microbiome Research (HUMI), Faculty of Medicine, University of Helsinki, Helsinki, Finland., Karisola P; Human Microbiome Research (HUMI), Faculty of Medicine, University of Helsinki, Helsinki, Finland., Lahti V; Human Microbiome Research (HUMI), Faculty of Medicine, University of Helsinki, Helsinki, Finland., Fyhrquist N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Laatikainen T; Department of Public Health Solutions, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Haahtela T; Skin and Allergy Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Alenius H; Human Microbiome Research (HUMI), Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: Frontiers in allergy [Front Allergy] 2022 Apr 27; Vol. 3, pp. 878862. Date of Electronic Publication: 2022 Apr 27 (Print Publication: 2022).

Transcriptomic Profiling of Adult-Onset Asthma Related to Damp and Moldy Buildings and Idiopathic Environmental Intolerance.

Autor: Suojalehto H; Occupational Medicine, Finnish Institute of Occupational Health, 00032 Helsinki, Finland., Ndika J; Human Microbiome (HUMI) Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland., Lindström I; Occupational Medicine, Finnish Institute of Occupational Health, 00032 Helsinki, Finland., Airaksinen L; Occupational Medicine, Finnish Institute of Occupational Health, 00032 Helsinki, Finland., Karvala K; Occupational Medicine, Finnish Institute of Occupational Health, 00032 Helsinki, Finland.; Varma, 00098 Helsinki, Finland., Kauppi P; Skin and Allergy Hospital, Helsinki University Hospital, 00250 Helsinki, Finland., Lauerma A; Skin and Allergy Hospital, Helsinki University Hospital, 00250 Helsinki, Finland., Toppila-Salmi S; Skin and Allergy Hospital, Helsinki University Hospital, 00250 Helsinki, Finland., Karisola P; Human Microbiome (HUMI) Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland., Alenius H; Human Microbiome (HUMI) Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.; Institute of Environmental Medicine (IMM), Karolinska Institutet, 171 77 Stockholm, Sweden.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Oct 01; Vol. 22 (19). Date of Electronic Publication: 2021 Oct 01.