Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nazzarena, Gasparini"'
Autor:
Marco Malavolta, Erminia Mariani, George Dedoussis, Robertina Giacconi, Tamas Fulop, Georges Herbein, Maurizio Cardelli, Francesco Piacenza, Laura Costarelli, Jolanta Jajte, Mauro Provinciali, Nazzarena Gasparini, Eugenio Mocchegiani, Franco Busco, Lothar Rink, Andrea Basso, Roberta Galeazzi
Publikováno v:
BioFactors. 41:414-423
Zinc dyshomeostasis may lead to an augmented production of proinflammatory cytokines promoting chronic inflammation and increasing the susceptibility to age-related diseases. Several studies suggest that the zinc transporter protein ZIP2 may play a r
Autor:
Lothar Rink, Marco Malavolta, Erminia Mariani, Franco Busco, George Dedoussis, Roberta Galeazzi, Tomas Fulop, Georges Herbein, Andrea Basso, Laura Costarelli, Eugenio Mocchegiani, Jolanta Jajte, Nazzarena Gasparini, Francesco Piacenza, Robertina Giacconi, Stavroula Kanoni
Publikováno v:
Biogerontology. 15:65-79
Proinflammatory cytokines and heat shock proteins play relevant roles in the pathogenesis of inflammatory diseases. We investigated whether Hsp70 1267 A/G and TNF-α -308 G/A polymorphisms are associated with proinflammatory mediators, zinc status an
Autor:
Robertina Giacconi, Nazzarena Gasparini, Monica Emanuelli, Roberta Papa, Eugenio Mocchegiani, Marco Malavolta, Laura Costarelli, Angela Polito, Francesca Maiani, Marco Boscaro, Francesco Piacenza, Fabrizia Lattanzio, Catia Cipriano, Emanuela Faloia, Giacomo Tirabassi, Silvia Tesei, Elisa Muti, Cinzia Giuli, Fiorella Marcellini, Beatrice Mauro, Anna Raguzzini, Sara Pierpaoli
Publikováno v:
The Journal of Nutritional Biochemistry. 21:432-437
Overweight and obesity are associated with low grade of inflammation and chronic inflammatory response characterized by abnormal production and activation of some pro-inflammatory signalling pathways. Taking into account that obesity is the direct re
Autor:
Laura Costarelli, Gianfranco Boccoli, Vittorio Saba, Nazzarena Gasparini, Eugenio Mocchegiani, Elisa Muti, Robertina Giacconi, Marco Malavolta, Gianni Bernardini, Erminia Mariani, Catia Cipriano
Publikováno v:
Molecular Medicine. 13:388-395
Carotid artery stenosis (CS) is a well-established risk factor for stroke. Increased proinflammatory chemokines, enhanced metallothionein (MT), and altered metal homeostasis may play roles in atherosclerosis progression and plaque destabilization. MT
Autor:
Robertina, Giacconi, Laura, Costarelli, Marco, Malavolta, Maurizio, Cardelli, Roberta, Galeazzi, Francesco, Piacenza, Nazzarena, Gasparini, Andrea, Basso, Erminia, Mariani, Tamas, Fulop, Lothar, Rink, George, Dedoussis, Georges, Herbein, Jolanta, Jajte, Mauro, Provinciali, Franco, Busco, Eugenio, Mocchegiani
Zinc dyshomeostasis may lead to an augmented production of proinflammatory cytokines promoting chronic inflammation and increasing the susceptibility to age-related diseases. Several studies suggest that the zinc transporter protein ZIP2 may play a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8111c68804abf42b879b26dcc5a35765
http://hdl.handle.net/11585/547230
http://hdl.handle.net/11585/547230
Autor:
Nazzarena Gasparini, Laura Costarelli, Daniela Monti, Maurizio Cardelli, Catia Cipriano, Elisa Muti, Eugenio Mocchegiani, Marco Malavolta, Erminia Mariani, Robertina Giacconi
Publikováno v:
Biogerontology. 7:357-365
Metallothioneins (MTs) play a pivotal role in zinc-related cell homeostasis because of their high affinity for zinc, which is in turn fundamental for immune response and antioxidant activity. MTs regulate zinc homeostasis by binding zinc and releasin
Autor:
Robertina Giacconi, Marco Malavolta, Elisa Muti, Laura Costarelli, Catia Cipriano, Nazzarena Gasparini, Cardelli Maurizio, Eugenio Mocchegiani, Vittorio Saba
Publikováno v:
Biogerontology. 6:407-413
Vascular complications, including ischaemic cardiomyopathy, are the major causes of death in old diabetic patients. Chronic inflammation due to high IL-6 production occurs in type 2 diabetes (NIDDM) and atherosclerosis. High levels of IL-6 are associ
Autor:
Claudio Franceschi, Elisabetta Cavalieri, Nazzarena Gasparini, Eugenio Mocchegiani, Robertina Giacconi, Catia Cipriano, Remo Gaetti, Mario Muzzioli, Hisanori Suzuki
Publikováno v:
Mechanisms of Ageing and Development. 124:459-468
Metallothioneins (MTs) play pivotal role in zinc-related cell homeostasis because of their high affinity for this trace element which is in turn relevant against oxidative stress and for the efficiency of the entire immune system, including natural k
Autor:
Leandro Provinciali, Nazzarena Gasparini, Robertina Giacconi, Mario Muzzioli, Liana Spazzafumo, Eugenio Mocchegiani, Federico Licastro
Publikováno v:
Mechanisms of Ageing and Development. 117:79-91
Different age-related immune pathogenetic mechanisms in myasthenia gravis (MG) have been suggested because of restoration after thymectomy (Tx) of altered zinc, thymulin (TH) and T-cell subsets exclusively in early-onset patients (younger50 years), n
Autor:
Eugenio Mocchegiani, Franco Busco, Marco Malavolta, Laura Costarelli, Nazzarena Gasparini, Gianni Bernardini, Roberta Galeazzi, Robertina Giacconi
Publikováno v:
The Journal of nutritional biochemistry. 23(10)
Intracellular zinc homeostasis is crucial in regulating the inflammatory/immune response at any age. It is tightly regulated by zinc transporters that control influx, efflux and compartmentalization of zinc within the cells. Specific methods for dete