Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Naznin Haq"'
Autor:
James B. Bussel, Hui Zhong, Naznin Haq, Karina Yazdanbakhsh, Weili Bao, Allison L. Miller, Xiaojuan Li, Caroline Seery
Publikováno v:
Blood. 120:3326-3335
Immune thrombocytopenia (ITP) results from decreased platelet production and accelerated platelet destruction. Impaired CD4+ regulatory T-cell (Treg) compartment and skewed Th1 and possibly Th17 responses have been described in ITP patients. The trig
Autor:
Wilhelm G. Dirks, Isabella Bambach, Helmut Bergler, Paul Vesely, Rene G. Ott, Philipp B. Staber, Silvia Schauer, Lukas Kenner, Veronika Sexl, Kotaro Funato, Marshall E. Kadin, Naznin Haq, Andelko Hrzenjak, Werner Linkesch, Gerald Hoefler, Claudia Fuchs, David W. Sternberg
Publikováno v:
Blood. 110:3374-3383
Anaplastic large cell lymphomas (ALCLs) are highly proliferating tumors that commonly express the AP-1 transcription factor JunB. ALK fusions occur in approximately 50% of ALCLs, and among these, 80% have the t(2;5) translocation with NPM-ALK express
Publikováno v:
Experimental Hematology. 42:S57
Background: Rituximab is an often effective treatment of ITP (Immune thrombocytopenia). However treated patients who respond often relapse. While they may have an almost identical response to retreatment, this includes relapsing again in the same tim
Autor:
Totan Kumar Ghosh, Naznin Haque Tompa, Md. Mezanur Rahman, Mohammed Mohi-Ud-Din, S. M. Zubair Al-Meraj, Md. Sanaullah Biswas, Mohammad Golam Mostofa
Publikováno v:
PeerJ, Vol 9, p e12419 (2021)
Liverwort Marchantia polymorpha is considered as the key species for addressing a myriad of questions in plant biology. Exploration of drought tolerance mechanism(s) in this group of land plants offers a platform to identify the early adaptive mechan
Externí odkaz:
https://doaj.org/article/b152e2aa70fd487fb810c96c76b80433
Autor:
Emily Leven, Nayla Boulad, James B. Bussel, Katayoun Rezvani, Nichola Cooper, David Marin, Shehzad Ahmad, Ruhena Sargent, Naznin Haq, Kate Stringaris, Bethan Psaila, Christina S. Lee
Publikováno v:
Blood. 122:2316-2316
The pathogenesis of immune thrombocytopenia (ITP) is multifactorial, with both cellular and humoural immune dysfunction. The role of NK cells has not been well defined in ITP but in other diseases NK cells have a role in rejecting “foreign” eg tr
Autor:
Claudia Tchatchouang, Naznin Haq, Allison A. Imahiyerobo, Micha Thompson, James B. Bussel, Catherine E. McGuinn
Publikováno v:
Blood. 122:3559-3559
Background Eltrombopag is an oral thrombopoietin receptor agonist which increases platelet counts in immune thrombocytopenia (ITP) patients by increasing proliferation of megakaryocyte (Mk) precursors and Mk. Maximal approved eltrombopag dosage in ch
Publikováno v:
Blood. 120:3327-3327
Abstract 3327 Introduction: Adult immune thrombocytopenia (ITP) is an autoimmune disorder characterized by an isolated low platelet count. Options for initial therapy in children and adults include corticosteroids (CS), intravenous immunoglobulin (IV
Publikováno v:
Blood. 120:2239-2239
Abstract 2239 Introduction: Socioeconomic, environmental, lifestyle and genetic factors play a role in the etiology of ITP but are poorly understood. A self-reported questionnaire was designed to study these relationships and how these factors prior
Autor:
David W. Sternberg, Greg Khitrov, Yezhou Sun, Weijia Zhang, Jin Chen, Kotaro Funato, Naznin Haq
Publikováno v:
Blood. 110:720-720
Nucleophosmin (NPM) exon 12 mutations are found in 50–60 percent of acute myelogenous leukemia (AML) with normal karyotype, and the altered protein (termed NPMc) is relocalized from the nucleolus to the cytoplasm. Multiple functions have been attri
Autor:
Naznin Haq, Nicole Duclos, Johannes Roesel, David W. Sternberg, Elizabeth McDowell, Patricia Imbach, Benjamin H. Lee, Arghya Ray, James D. Griffin, Jennifer Adelsperger, Markus Warmuth, Osamu Ohmori, Doriano Fabbro, Toshiyuki Honda
Publikováno v:
Blood. 108:828-828
Anaplastic large cell lymphoma (ALCL) constitutes approximately 10–30 percent of childhood lymphomas and 3 percent of non-Hodgkin lymphomas in adults. Approximately 50–60 percent of ALCL patients express the ALK tyrosine kinase fused to a variety