Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nazmul H. Bhuiyan"'
Autor:
Y u Okashita, Hiroyuki Ishida, Hiromi Ishida, Amane Makino, Makoto Hayashi, Klaas J. van Wijk, Nazmul H. Bhuiyan, Masanori Izumi
Publikováno v:
Plantcell physiology. 62(9)
Chloroplasts, and plastids in general, contain abundant protein pools that can be major sources of carbon and nitrogen for recycling. We have previously shown that chloroplasts are partially and sequentially degraded by piecemeal autophagy via the Ru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826b16dca121d24b331274d0a4cd3254
https://pubmed.ncbi.nlm.nih.gov/34086965
https://pubmed.ncbi.nlm.nih.gov/34086965
Autor:
Elden Rowland, Klaas J. van Wijk, Nazmul H. Bhuiyan, Lalit Ponnala, Elena J.S. Michel, Giulia Friso
Publikováno v:
Plant Physiol
Chloroplast proteostasis is governed by a network of peptidases. As a part of this network, we show that Arabidopsis (Arabidopsis thaliana) chloroplast glutamyl peptidase (CGEP) is a homo-oligomeric stromal Ser-type (S9D) peptidase with both exo- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977d8b01659c9f0545ea49aeb3951813
https://pubmed.ncbi.nlm.nih.gov/32663165
https://pubmed.ncbi.nlm.nih.gov/32663165
Autor:
Dan Luo, George R. Uhl, David O. Johnson, Chamani Perera, Jane Smoake, Fangchao Bi, Fanxun Zeng, Nazmul H. Bhuiyan, Wei Wang, Thomas E. Prisinzano, Ian M. Henderson, Maria Carmen Martinez
Publikováno v:
Biochem Pharmacol
Interest in development of potent, selective inhibitors of the phosphatase from the receptor type protein tyrosine phosphatase PTPRD as antiaddiction agents is supported by human genetics, mouse models and studies of our lead compound PTPRD phosphata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680d90bdf8f7886e985572f3b596f328
https://doi.org/10.1016/j.bcp.2021.114868
https://doi.org/10.1016/j.bcp.2021.114868
Autor:
Nazmul H. Bhuiyan, Michelle L. Varney, Sarah A. Holstein, Daniel B. Goetz, Alisa E.R. Fairweather, David F. Wiemer, Chloe M. Schroeder
Publikováno v:
Bioorg Med Chem
Agents that inhibit the enzyme geranylgeranyl diphosphate synthase (GGDPS) have anti-cancer activity and our prior studies have investigated the structure-function relationship for a family of isoprenoid triazole bisphosphonates as GGDPS inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e9a9bf0d666ffdbf24d72ab7745847
https://doi.org/10.1016/j.bmc.2021.116307
https://doi.org/10.1016/j.bmc.2021.116307
Autor:
Sarah A. Holstein, David F. Wiemer, Deep S. Bhattacharya, William M. Payne, Nazmul H. Bhuiyan, Aaron M. Mohs, Michelle L. Varney
Publikováno v:
Bioorg Med Chem Lett
The enzyme geranylgeranyl diphosphate synthase (GGDPS) is a potential therapeutic target for multiple myeloma. Malignant plasma cells produce and secrete large amounts of monoclonal protein, and inhibition of GGDPS results in disruption of protein ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9459836f1ea768c02c04c5c958d142
https://pubmed.ncbi.nlm.nih.gov/31474482
https://pubmed.ncbi.nlm.nih.gov/31474482
Publikováno v:
The Plant Cell. 27:262-285
Photosystem II (PSII) requires constant disassembly and reassembly to accommodate replacement of the D1 protein. Here, we characterize Arabidopsis thaliana MET1, a PSII assembly factor with PDZ and TPR domains. The maize (Zea mays) MET1 homolog is en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4d349ad662c39fe7fb647ffb495ff7
https://doi.org/10.1105/tpc.114.132787
https://doi.org/10.1105/tpc.114.132787
Autor:
Klaas J. van Wijk, Nazmul H. Bhuiyan
Plastoglobules (PGs) in chloroplasts are monolayer lipid-protein particles attached to thylakoids. The size and number of PGs per chloroplast respond dynamically to abiotic environmental stresses and developmental transitions. During senescence, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63eaafe35bbe86e80d25033c2c3b40bf
https://europepmc.org/articles/PMC5566252/
https://europepmc.org/articles/PMC5566252/
Autor:
Doreen Ware, Qi Sun, Nazmul H. Bhuiyan, Klaas J. van Wijk, Sunita Kumari, Kristina Majsec, Vivek Kumar
Plant plastids and mitochondria have dynamic proteomes. Protein homeostasis in these organelles is maintained by a proteostasis network containing protein chaperones, peptidases, and their substrate recognition factors. However, many peptidases, as w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780afc76cc5809f9938880de509618fa
https://doi.org/10.1105/tpc.17.00481
https://doi.org/10.1105/tpc.17.00481
Publikováno v:
Bioorg Med Chem Lett
Benzimidazole carboxyphosphonates and bisphosphonates have been prepared and evaluated for their activity as inhibitors of protein prenylation or isoprenoid biosynthesis. The nature of the phosphonate head group was found to dictate enzyme specificit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb954da6fd0277f55dfd58ab85e47a58
https://doi.org/10.1016/j.bmcl.2019.126757
https://doi.org/10.1016/j.bmcl.2019.126757
Autor:
Qi Sun, Klaas J. van Wijk, Peter K. Lundquist, Anton Poliakov, Nazmul H. Bhuiyan, Boris Zybailov
Publikováno v:
Plant Physiology. 158:1172-1192
Plastoglobules (PGs) in chloroplasts are thylakoid-associated monolayer lipoprotein particles containing prenyl and neutral lipids and several dozen proteins mostly with unknown functions. An integrated view of the role of the PG is lacking. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d91cf77be7adac1ded4f7c5493661c
https://doi.org/10.1104/pp.111.193144
https://doi.org/10.1104/pp.111.193144