Výsledky vyhledávání

IVF characteristics and the molecular luteal features of random start IVF cycles are not different from conventional cycles in cancer patients

Autor: Yashar Esmaeilian, Francesko Hela, Gamze Bildik, Nazli Akin, Ece İltumur, Sevgi Yusufoglu, Ceren Sultan Yildiz, İpek Keles, Dogan Vatansever, Cagatay Taskiran, Kayhan Yakin, Ozgur Oktem

Publikováno v: Human Reproduction. 38:113-124

STUDY QUESTION Are the IVF parameters and the steroidogenic luteal characteristics of random-start IVF cycles different from conventional cycles in cancer patients? SUMMARY ANSWER No; controlled ovarian stimulation cycles randomly started at late fol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274b097fef5134a8e6a64ae05bf46475
https://doi.org/10.1093/humrep/deac242

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Cholesterol uptake or trafficking, steroid biosynthesis, and gonadotropin responsiveness are defective in young poor responders

Autor: Gamze Bildik, Yashar Esmaeilian, Francesko Hela, Nazli Akin, Ece İltumur, Sevgi Yusufoglu, Ceren Sultan Yildiz, Kayhan Yakin, Ozgur Oktem

Publikováno v: Fertility and Sterility. 117:1069-1080

To investigate whether poor ovarian response in young patients undergoing in vitro fertilization simply involves lesser follicle growth due to diminished ovarian reserve or whether there are intrinsic perturbations in the ovary.A translational resear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b591900b882e1653e527678d80754223
https://doi.org/10.1016/j.fertnstert.2022.01.024

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Effect of cumulin and super-GDF9 in standard and biphasic mouse IVM

Autor: Nazli Akin, Dulama Richani, Xiuhua Liao, Yiqing Zhao, Anamaria-Cristina Herta, Katy Billooye, William A. Stocker, David G. Mottershead, Craig A. Harrison, Johan Smitz, Ellen Anckaert, Robert B. Gilchrist

Publikováno v: J Assist Reprod Genet

PURPOSE: In vitro maturation (IVM) is a technology that generates mature oocytes following culture of immature cumulus-oocyte complexes (COC) in vitro. IVM is characterized by minimal patient stimulation, making it attractive for certain patient grou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b218e197beef699fb7d92c9f8806cafa
https://doi.org/10.1007/s10815-021-02382-z

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Glucose metabolism characterization during mouse in vitro maturation identifies alterations in cumulus cells†

Autor: Fábio Klamt, Johan Smitz, Anamaria-Cristina Herta, Nazli Akin, Laura Saucedo-Cuevas, Julia Leersum, Berta Cava-Cami, Lucia von Mengden, Ellen Anckaert, Katy Billooye

Publikováno v: Biology of Reproduction. 104:902-913

In vitro maturation (IVM) is an assisted reproduction technique with reduced hormone-related side-effects. Several attempts to implement IVM in routine practice have failed, primarily due to its relatively low efficiency compared with conventional in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee51369e09653909c402afba42ab12d
https://doi.org/10.1093/biolre/ioab008

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Terminal differentiation of human granulosa cells as luteinization is reversed by activin-A through silencing of Jnk pathway

Autor: Yashar Esmaeilian, Francesko Hela, Ozgur Oktem, Gamze Bildik, Said Incir, Ceren Sultan Yildiz, Kayhan Yakin, Sercin Karahuseyinoglu, Ece Iltumur, Nazli Akin

Publikováno v: Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Cell Death Discovery

Molecular mechanisms underlying luteinization (terminal differentiation of granulosa and theca cells after ovulation) and luteolysis (demise of corpus luteum) are poorly understood in human ovary. Here we report that activin-A, after binding to its c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5b047ec955fd7f8cfab92248cb7287
http://link.springer.com/article/10.1038/s41420-020-00324-9

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Positive effects of amphiregulin on human oocyte maturation and its molecular drivers in patients with polycystic ovary syndrome

Autor: Flor Sanchez, Lan N. Vuong, Minh Hoang Nhat Nguyen, Tuong M Ho, Johan Smitz, Nazli Akin, A. Le, Sergio Romero, Ellen Anckaert, Toan D Pham, Uyen D T Ha

STUDY QUESTION Does use of medium containing amphiregulin improve meiotic maturation efficiency in oocytes of women with polycystic ovary syndrome (PCOS) undergoing in vitro maturation (IVM) preceded by a capacitation culture step capacitation IVM (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c598e2c624add139d47d7131572a94
https://doi.org/10.1093/humrep/deab237

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P–439 Carbohydrate metabolism profile during oocyte final maturation reveals culture induced aberrations in in vitro grown and matured mouse antral follicles

Autor: Nazli Akin, B Cava-Cami, Ellen Anckaert, L Vo. Mengden, Anamaria-Cristina Herta, Fábio Klamt, Johan Smitz, J Va. Leersum, Marie-Madeleine Dolmans, Katy Billooye, Laura Saucedo-Cuevas

Publikováno v: Human Reproduction. 36

Study question Are there significant differences in carbohydrate metabolism trends between in vivo and in vitro grown mouse antral follicles during oocyte final maturation? Summary answer Glucose metabolism characterization during GV to MII transitio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d34e435570870db759ff5f2fda6b33a
https://doi.org/10.1093/humrep/deab130.438

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Reversing complete mechanical transzonal projections disruption during mouse in vitro follicle culture with unaltered oocyte competence

Autor: Ingrid Segers, Laura Saucedo-Cuevas, Nazli Akin, Ellen Anckaert, Francesca Lolicato, Anamaria-Cristina Herta, Johan Smitz, Katy Billooye

In vitro oocyte growth is widely studied as an alternative fertility preservation approach. Several animal models are used to generate extensive information on this complex process regulated by the constant and dynamic interaction between the oocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb33fda2bc5130b95873636ecff1f03
https://hdl.handle.net/20.500.14017/5100ff6d-50c3-43c9-afbf-2373b26b6e8c

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