Výsledky vyhledávání - "Nazish U. Tanoli"

Characterization of the interactions between coumarin-derivatives and acetylcholinesterase: Examination by NMR and docking simulations

Autor: Julia L. Monteiro, Mazhar Mehmood, Sheraz A. K. Tanoli, Tiago Venâncio, Zaheer Ul-Haq, Sana Gul, Nazish U. Tanoli, Antonio G. Ferreira, Arlene G. Corrêa, Lucas Campos Curcino Vieira

Publikováno v: Journal of Molecular Modeling. 24

Alzheimer’s disease (AD) is one of the most common forms of dementia and a significant threat to the elderly populations, especially in the Western world. The rapid hydrolysis of the principal neurotransmitter into choline and acetate by acetylchol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629c67e60cbb110909d6b1d520365af7
https://doi.org/10.1007/s00894-018-3751-3

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Evaluation of binding competition and group epitopes of acetylcholinesterase inhibitors by STD NMR, Tr-NOESY, DOSY and molecular docking: an old approach but new findings

Autor: Zaheer Ul-Haq, Sana Gul, Sheraz A. K. Tanoli, Antonio G. Ferreira, Nazish U. Tanoli

Publikováno v: MedChemComm. 6:1882-1890

Acetylcholinesterase is an important enzyme, currently used as therapy for controlling the effects of Alzheimer's disease that has been accepted as one of the major threats to the elderly population. In this perspective, NMR-based binding studies wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e045f3ea867e5ce165e9a37863a3b991
https://doi.org/10.1039/c5md00231a

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Human serum albumin-specific recognition of the natural herbal extract of Stryphnodendron polyphyllum through STD NMR, hyphenations and docking simulation studies

Autor: João B. Fernandes, Sheraz A. K. Tanoli, Saman Usmani, Nazish U. Tanoli, Zaheer Ul-Haq, Tatiani M. Bondancia, Antonio G. Ferreira, Sérgio Scherrer Thomasi

Publikováno v: RSC Advances. 5:23431-23442

Over the last two decades, new and more advanced strategies that help in the rapid screening and identification of new ligands for a specific macromolecule have become an important domain. From this viewpoint, the effectiveness of STD NMR, Tr-NOESY,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0da715c0152dbea47fc4b60727113f21
https://doi.org/10.1039/c5ra01457c

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The exploration of interaction studies of smaller size, mostly ignored yet intrinsically inestimable molecules towards BSA; An example of STD and DOSY NMR

Autor: Sheraz A. K. Tanoli, Saman Usmani, Nazish U. Tanoli, Antonio G. Ferreira, Zaheer-Ul-Haq

Publikováno v: Open Chemistry, Vol 12, Iss 3, Pp 332-340 (2014)

Larger size or novel structure molecules are always appreciated by all fields of experimental and computational science. Conversely, molecules with smaller size and simple structures are usually ignored with no explanation as to why. However, the vas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda99411814ec487e0961fdaacecef07
https://doi.org/10.2478/s11532-013-0380-7

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Crude to leads: a triple-pronged direct NMR approach in coordination with docking simulation

Autor: Nazish U. Tanoli, Zaheer Ul-Haq, Antonio G. Ferreira, Saman Usmani, Sheraz A. K. Tanoli, João B. Fernandes, Tatiani M. Bondancia, Rainer Kerssebaum

Publikováno v: The Analyst. 138:5137

The screening of compounds that bind to the target of interest (specific proteins) plays a vital role in drug discovery. Usually, the identification of biologically active compounds is done from a library of structurally known compounds. However, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a082af582e6d81f19feb740a0365608b
https://doi.org/10.1039/c3an00728f

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