Trigonelline, a plant derived alkaloid prevents ultraviolet-B-induced oxidative DNA damage in primary human dermal fibroblasts and BALB/c mice via modulation of phosphoinositide 3-kinase-Akt-Nrf2 signalling axis.

Autor: Tanveer MA; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, Jammu & Kashmir, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Rashid H; Department of Hospital Adminstration, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Soura, Srinagar 190011, Jammu & Kashmir, India. Electronic address: haroonallied@gmail.com., Nazir LA; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, Jammu & Kashmir, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Archoo S; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, Jammu & Kashmir, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Shahid NH; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, Jammu & Kashmir, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Ragni G; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, Jammu & Kashmir, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Umar SA; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, Jammu & Kashmir, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Tasduq SA; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, Jammu & Kashmir, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: stabdullah@iiim.res.in.

Publikováno v: Experimental gerontology [Exp Gerontol] 2023 Jan; Vol. 171, pp. 112028. Date of Electronic Publication: 2022 Nov 13.

Pharmacological Activation of Autophagy Restores Cellular Homeostasis in Ultraviolet-(B)-Induced Skin Photodamage.

Autor: Umar SA; Biological Sciences, Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India.; Pharmacokinetics-Pharmacodynamics (PK-PD) and Toxicology Division, Council of Scientific & Industrial Research (CSIR)-Indian Institute of Integrative Medicine, Jammu Tawi, India., Shahid NH; Biological Sciences, Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India.; Pharmacokinetics-Pharmacodynamics (PK-PD) and Toxicology Division, Council of Scientific & Industrial Research (CSIR)-Indian Institute of Integrative Medicine, Jammu Tawi, India., Nazir LA; Biological Sciences, Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India.; Pharmacokinetics-Pharmacodynamics (PK-PD) and Toxicology Division, Council of Scientific & Industrial Research (CSIR)-Indian Institute of Integrative Medicine, Jammu Tawi, India., Tanveer MA; Biological Sciences, Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India.; Pharmacokinetics-Pharmacodynamics (PK-PD) and Toxicology Division, Council of Scientific & Industrial Research (CSIR)-Indian Institute of Integrative Medicine, Jammu Tawi, India., Divya G; Biological Sciences, Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India.; Pharmacokinetics-Pharmacodynamics (PK-PD) and Toxicology Division, Council of Scientific & Industrial Research (CSIR)-Indian Institute of Integrative Medicine, Jammu Tawi, India., Archoo S; Biological Sciences, Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India.; Pharmacokinetics-Pharmacodynamics (PK-PD) and Toxicology Division, Council of Scientific & Industrial Research (CSIR)-Indian Institute of Integrative Medicine, Jammu Tawi, India., Raghu SR; Biological Sciences, Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India.; Pharmacokinetics-Pharmacodynamics (PK-PD) and Toxicology Division, Council of Scientific & Industrial Research (CSIR)-Indian Institute of Integrative Medicine, Jammu Tawi, India., Tasduq SA; Biological Sciences, Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India.; Pharmacokinetics-Pharmacodynamics (PK-PD) and Toxicology Division, Council of Scientific & Industrial Research (CSIR)-Indian Institute of Integrative Medicine, Jammu Tawi, India.

Publikováno v: Frontiers in oncology [Front Oncol] 2021 Aug 02; Vol. 11, pp. 726066. Date of Electronic Publication: 2021 Aug 02 (Print Publication: 2021).

The amino analogue of β-boswellic acid efficiently attenuates the release of pro-inflammatory mediators than its parent compound through the suppression of NF-κB/IκBα signalling axis.

Autor: Gupta S; Academy of Scientific and Innovative Research, CSIR-Indian Institute of Integrative Medicines, India; Inflammation Pharmacology Division, CSIR-Indian Institute of Integrative Medicines, India., Ahsan AU; Cytogenetics Lab, Department of Zoology, Panjab University, Chandigarh, India., Wani A; Academy of Scientific and Innovative Research, CSIR-Indian Institute of Integrative Medicines, India; CancerPharmacology Division, CSIR-Indian Institute of Integrative Medicines, India., Khajuria V; Academy of Scientific and Innovative Research, CSIR-Indian Institute of Integrative Medicines, India; Inflammation Pharmacology Division, CSIR-Indian Institute of Integrative Medicines, India., Nazir LA; Academy of Scientific and Innovative Research, CSIR-Indian Institute of Integrative Medicines, India; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, India., Sharma S; Natural Product Microbes, CSIR-Indian Institute of Integrative Medicines, India., Bhagat A; Inflammation Pharmacology Division, CSIR-Indian Institute of Integrative Medicines, India., Raj Sharma P; CancerPharmacology Division, CSIR-Indian Institute of Integrative Medicines, India., Bhardwaj S; Department of Pathology, Government Medical College Jammu, India., Peerzada KJ; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, India., Ali Shah B; Natural Product Microbes, CSIR-Indian Institute of Integrative Medicines, India., Ahmed Z; Inflammation Pharmacology Division, CSIR-Indian Institute of Integrative Medicines, India. Electronic address: zahmed@iiim.ac.in.

Publikováno v: Cytokine [Cytokine] 2018 Jul; Vol. 107, pp. 93-104. Date of Electronic Publication: 2017 Dec 08.

Glycyrrhizic acid prevents ultraviolet-B-induced photodamage: a role for mitogen-activated protein kinases, nuclear factor kappa B and mitochondrial apoptotic pathway.

Autor: Afnan Q; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Jammu Tawi, Jammu and Kashmir, India.; Department of Biochemistry, Panjab University, Chandigarh, India., Kaiser PJ; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Jammu Tawi, Jammu and Kashmir, India., Rafiq RA; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Jammu Tawi, Jammu and Kashmir, India., Nazir LA; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Jammu Tawi, Jammu and Kashmir, India.; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India., Bhushan S; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.; Cancer Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Jammu Tawi, Jammu and Kashmir, India., Bhardwaj SC; Department of Pathology, Government Medical College, Jammu, Jammu and Kashmir, India., Sandhir R; Department of Biochemistry, Panjab University, Chandigarh, India., Tasduq SA; PK-PD and Toxicology Division, CSIR-Indian Institute of Integrative Medicine, Jammu Tawi, Jammu and Kashmir, India.; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.

Publikováno v: Experimental dermatology [Exp Dermatol] 2016 Jun; Vol. 25 (6), pp. 440-6.