Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Nazir A, Ismail"'
Autor:
Norbert Ndjeka, Nazir A Ismail
Publikováno v:
The Lancet Microbe, Vol 1, Iss 4, Pp e139-e140 (2020)
Externí odkaz:
https://doaj.org/article/144b6399bbd4410a8af8738cd890e720
Autor:
Nazir A. Ismail, Shaheed V. Omar, Lavania Joseph, Netricia Govender, Linsay Blows, Farzana Ismail, Hendrik Koornhof, Andries W. Dreyer, Koné Kaniga, Norbert Ndjeka
Publikováno v:
EBioMedicine, Vol 28, Iss C, Pp 136-142 (2018)
Background: Bedaquiline (BDQ) is a novel agent approved for use in combination treatment of multi-drug resistant tuberculosis (MDR-TB). We sought to determine BDQ epidemiological cut-off values (ECVs), define and assess interpretive criteria against
Externí odkaz:
https://doaj.org/article/eebca42cbced4a99b05f59a28094c997
Autor:
Shaheed V. Omar, Lavania Joseph, Halima M. Said, Farzana Ismail, Nabila Ismail, Thabisile L. Gwala, Nazir A. Ismail
Publikováno v:
African Journal of Laboratory Medicine, Vol 8, Iss 1, Pp e1-e5 (2019)
South Africa remains challenged with a high tuberculosis burden accompanied by an increase in drug resistant cases. We assessed the use of the Illumina MiSeq, a next-generation sequencing platform for whole genome sequencing, followed by bioinformati
Externí odkaz:
https://doaj.org/article/923a544b5bf5434290ae0ab46ee11323
Autor:
Harry Moultrie, Ebrahim Variava, Zaheda Bhyat., Martin Enwerem, Simon Schaaf, Xavier Padanilam, Norbert Ndjeka, Nana Okozi, Minty van der Meulen, Lavania Joseph, Yulene Kock, Shaheed V. Omar, Nazir Ahmed Ismail, Hannetjie Ferreira, Francesca Conradie, Vancy Letsaolo, Anja Reuter, Gary Maartens, Farzana Ismail, Jennifer Hughes, Julian Te Riele, Rodolf Romero, Graeme Meintjes, Dumisani Ngcamu
Publikováno v:
The Lancet Infectious Diseases. 22:496-506
Summary Background Bedaquiline improves outcomes of patients with rifampicin-resistant and multidrug-resistant (MDR) tuberculosis; however, emerging resistance threatens this success. We did a cross-sectional and longitudinal analysis evaluating the
Autor:
Alena Skrahina, Sabira Tahseen, Roger Vargas, Daniela Maria Cirillo, S.M. Mostofa Kamal, Matteo Zignol, Anna S. Dean, Stefan Niemann, Luca Freschi, Ashaque Husain, Nazir Ahmed Ismail, Maha R. Farhat, Anna Barbova
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
Mycobacterium tuberculosis is a clonal pathogen proposed to have co-evolved with its human host for millennia, yet our understanding of its genomic diversity and biogeography remains incomplete. Here we use a combination of phylogenetics and dimensio
Autor:
Erika Britz, Olga Perovic, Claire von Mollendorf, Anne von Gottberg, Samantha Iyaloo, Vanessa Quan, Verushka Chetty, Charlotte Sriruttan, Nazir A Ismail, Ananta Nanoo, Alfred Musekiwa, Carl Reddy, Karien Viljoen, Cheryl Cohen, Nelesh P Govender
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163036 (2016)
INTRODUCTION:Meningitis is a major cause of mortality in southern Africa. We aimed to describe the aetiologies and frequencies of laboratory-confirmed fungal and bacterial meningitis among adults in a South African province with an 11% HIV prevalence
Externí odkaz:
https://doaj.org/article/3e47cf96aba244eaa86d5af92d81ea98
Autor:
Halima M Said, Nicole Kushner, Shaheed V Omar, Andries W Dreyer, Hendrik Koornhof, Linda Erasmus, Yasmin Gardee, Ivy Rukasha, Elena Shashkina, Natalie Beylis, Gilla Kaplan, Dorothy Fallows, Nazir A Ismail
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146106 (2016)
In South Africa and other high prevalence countries, transmission is a significant contributor to rising rates of multidrug resistant tuberculosis (MDR-TB). Thus, there is a need to develop an early detection system for transmission clusters suitable
Externí odkaz:
https://doaj.org/article/7725a3f2f8a044a2853ebb25af765205
Autor:
Ruth S. Mpembe, Gal Feller, Erika van Schalkwyk, Ashika Singh-Moodley, Onnicah Matuka, Serisha D. Naicker, Arshad Ismail, Liliwe Shuping, Wilhelmina Strasheim, F. Ismail, Tsidiso G. Maphanga, Nelesh P. Govender, Thabang Duba, Ruth Mogokotleng, Olga Perovic, Nazir Ahmed Ismail, Mushal Allam, Michelle Lowe, Cecilia De Abreu, Itumeleng Moema, Husna Ismail, Tanusha S. Singh
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-13 (2020)
BMC Infectious Diseases
BMC Infectious Diseases
Background We aimed to describe an outbreak of cutaneous abscesses caused by Panton-Valentine leukocidin (PVL)-producing methicillin-susceptible Staphylococcus aureus (MSSA) among gold mine workers. Methods In February 2018, we retrospectively review
Autor:
Rachel M Wake, Nazir A Ismail, Shaheed V Omar, Farzana Ismail, Caroline T Tiemessen, Thomas S Harrison, Joseph N Jarvis, Nelesh P Govender
Publikováno v:
Open forum infectious diseases. 9(7)
The greater mortality risk among people with advanced human immunodeficiency virus disease and cryptococcal antigenemia, despite treatment, indicates an increased susceptibility to other infections. We found that prior tuberculosis was an independent
Autor:
Ruwen Jou, Hulya Simsek, Saijai Smithtikarn, Laima Vasiliauskaitė, Camilla Rodrigues, Rumina Hasan, Phalin Kamolwat, Charoen Chuchottaworn, Beverly Metchock, Koné Kaniga, Edita Vasiliauskienė, Greta Musteikiene, Jirakan Boonyasopun, Mubin Kazi, Catherine Ann Sacopon, Nguyen Viet Nhung, Seungmo Kim, Shaheed V. Omar, Anh Le Thi Ngoc, So Youn Shin, Sabira Tahseen, Skaidrius Miliauskas, Mei-Hua Wu, Nazir Ahmed Ismail
Publikováno v:
Journal of Clinical Microbiology. 60
Bedaquiline Drug Resistance Emergence Assessment in Multidrug-resistant-tuberculosis (MDR-TB) (DREAM) was a 5-year (2015-2019) phenotypic drug-resistance surveillance study across 11 countries. DREAM assessed the susceptibility of 5036 MDR-TB isolate