Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Naziia, Kurmasheva"'
Autor:
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Anna H. F. Rahimic, Alena Kress, Madalina E. Carter-Timofte, Emilia Holm, Demi van der Horst, Christoph F. Kollmann, Zhenlong Liu, Chen Wang, Huy-Dung Hoang, Elina Kovalenko, Maria Chrysopoulou, Krishna Sundar Twayana, Rasmus N. Ottosen, Esben B. Svenningsen, Fabio Begnini, Anders E. Kiib, Florian E. H. Kromm, Hauke J. Weiss, Daniele Di Carlo, Michela Muscolini, Maureen Higgins, Mirte van der Heijden, Angelina Bardoul, Tong Tong, Attila Ozsvar, Wen-Hsien Hou, Vivien R. Schack, Christian K. Holm, Yunan Zheng, Melanie Ruzek, Joanna Kalucka, Laureano de la Vega, Walid A. M. Elgaher, Anders R. Korshoej, Rongtuan Lin, John Hiscott, Thomas B. Poulsen, Luke A. O’Neill, Dominic G. Roy, Markus M. Rinschen, Nadine van Montfoort, Jean-Simon Diallo, Henner F. Farin, Tommy Alain, David Olagnier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-28 (2024)
Abstract The presence of heterogeneity in responses to oncolytic virotherapy poses a barrier to clinical effectiveness, as resistance to this treatment can occur through the inhibition of viral spread within the tumor, potentially leading to treatmen
Externí odkaz:
https://doaj.org/article/cf343351f5cf4766ad351ee93729ee99
Autor:
Demi van der Horst, Naziia Kurmasheva, Mikkel H. S. Marqvorsen, Sonia Assil, Anna H. F. Rahimic, Christoph F. Kollmann, Leandro Silva da Costa, Qi Wu, Jian Zhao, Eleonora Cesari, Marie B. Iversen, Fanghui Ren, Trine I. Jensen, Ryo Narita, Vivien R. Schack, Bao-cun Zhang, Rasmus O. Bak, Claudio Sette, Robert A. Fenton, Jacob G. Mikkelsen, Søren R. Paludan, David Olagnier
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract DNA is a danger signal sensed by cGAS to engage signaling through STING to activate innate immune functions. The best-studied downstream responses to STING activation include expression of type I interferon and inflammatory genes, but STING
Externí odkaz:
https://doaj.org/article/0db80e2a99374afa9c136a61eb6b74e2
Autor:
Nadine Vollmuth, Lisa Schlicker, Yongxia Guo, Pargev Hovhannisyan, Sudha Janaki-Raman, Naziia Kurmasheva, Werner Schmitz, Almut Schulze, Kathrin Stelzner, Karthika Rajeeve, Thomas Rudel
Publikováno v:
eLife, Vol 11 (2022)
Chlamydia trachomatis (Ctr) can persist over extended times within their host cell and thereby establish chronic infections. One of the major inducers of chlamydial persistence is interferon-gamma (IFN-γ) released by immune cells as a mechanism of i
Externí odkaz:
https://doaj.org/article/b5901aba18994e7e8ed2c8f6ada5ed36
Autor:
Zaid Taha, Rozanne Arulanandam, Glib Maznyi, Elena Godbout, Madalina E. Carter-Timofte, Naziia Kurmasheva, Line S. Reinert, Andrew Chen, Mathieu J.F. Crupi, Stephen Boulton, Geneviève Laroche, Alexandra Phan, Reza Rezaei, Nouf Alluqmani, Anna Jirovec, Alexandra Acal, Emily E.F. Fekete, Ragunath Singaravelu, Julia Petryk, Manja Idorn, Kyle G. Potts, Hayley Todesco, Cini John, Douglas J. Mahoney, Carolina S. Ilkow, Patrick Giguère, Tommy Alain, Marceline Côté, Søren R. Paludan, David Olagnier, John C. Bell, Taha Azad, Jean-Simon Diallo
Publikováno v:
Taha, Z, Arulanandam, R, Maznyi, G, Godbout, E, Carter-Timofte, M E, Kurmasheva, N, Reinert, L S, Chen, A, Crupi, M J F, Boulton, S, Laroche, G, Phan, A, Rezaei, R, Alluqmani, N, Jirovec, A, Acal, A, Brown, E E F, Singaravelu, R, Petryk, J, Idorn, M, Potts, K G, Todesco, H, John, C, Mahoney, D J, Ilkow, C S, Giguère, P, Alain, T, Côté, M, Paludan, S R, Olagnier, D, Bell, J C, Azad, T & Diallo, J-S 2022, ' Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen ', Molecular Therapy, vol. 30, no. 9, pp. 2998-3016 . https://doi.org/10.1016/j.ymthe.2022.04.025
We established a split nanoluciferase complementation assay to rapidly screen for inhibitors that interfere with binding of the receptor binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d052687f015e890d9f0b9d825f8eed66
https://doi.org/10.1016/j.ymthe.2022.04.025
https://doi.org/10.1016/j.ymthe.2022.04.025
Autor:
Stephen Boulton, Mathieu J.F. Crupi, Siddharth Singh, Madalina E. Carter-Timofte, Taha Azad, Bailey C. Organ, Xiaohong He, Rida Gill, Serge Neault, Taylor Jamieson, Jaahnavi Dave, Naziia Kurmasheva, Bradley Austin, Julia Petryk, Ragunath Singaravelu, Ben Zhen Huang, Noah Franco, Kaaviya Babu, Robin J. Parks, Carolina S. Ilkow, David Olagnier, John C. Bell
Publikováno v:
Boulton, S, Crupi, M J F, Singh, S, Carter-Timofte, M E, Azad, T, Organ, B C, He, X, Gill, R, Neault, S, Jamieson, T, Dave, J, Kurmasheva, N, Austin, B, Petryk, J, Singaravelu, R, Huang, B Z, Franco, N, Babu, K, Parks, R J, Ilkow, C S, Olagnier, D & Bell, J C 2023, ' Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development ', The Journal of Biological Chemistry, vol. 299, no. 6, 104749 . https://doi.org/10.1016/j.jbc.2023.104749
The recent SARS-CoV-2 and mpox outbreaks have highlighted the need to expand our arsenal of broad-spectrum antiviral agents for future pandemic preparedness. Host-directed antivirals are an important tool to accomplish this as they typically offer pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b32745bd6947ccc21790ccd5e16728a
https://pure.au.dk/portal/da/publications/inhibition-of-exchange-proteins-directly-activated-by-camp-as-a-strategy-for-broadspectrum-antiviral-development(6acf2940-262b-421c-9f4c-6c2678322a6a).html
https://pure.au.dk/portal/da/publications/inhibition-of-exchange-proteins-directly-activated-by-camp-as-a-strategy-for-broadspectrum-antiviral-development(6acf2940-262b-421c-9f4c-6c2678322a6a).html
Autor:
Markus M. Rinschen, Jennifer L. Harder, Madalina E. Carter-Timofte, Luis Zanon Rodriguez, Carmen Mirabelli, Fatih Demir, Naziia Kurmasheva, Suresh K. Ramakrishnan, Madlen Kunke, Yifan Tan, Anja Billing, Eileen Dahlke, Alexey A. Larionov, Wibke Bechtel-Walz, Ute Aukschun, Marlen Grabbe, Rikke Nielsen, Erik I. Christensen, Matthias Kretzler, Tobias B. Huber, Christiane E. Wobus, David Olagnier, Gary Siuzdak, Florian Grahammer, Franziska Theilig
Publikováno v:
Rinschen, M M, Harder, J L, Carter-Timofte, M E, Zanon Rodriguez, L, Mirabelli, C, Demir, F, Kurmasheva, N, Ramakrishnan, S K, Kunke, M, Tan, Y, Billing, A, Dahlke, E, Larionov, A A, Bechtel-Walz, W, Aukschun, U, Grabbe, M, Nielsen, R, Christensen, E I, Kretzler, M, Huber, T B, Wobus, C E, Olagnier, D, Siuzdak, G, Grahammer, F & Theilig, F 2022, ' VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney ', Science Signaling, vol. 15, no. 762, pp. eabo7940 . https://doi.org/10.1126/scisignal.abo7940
The lipid kinase VPS34 orchestrates autophagy, endocytosis, and metabolism and is implicated in cancer and metabolic disease. The proximal tubule in the kidney is a key metabolic organ that controls reabsorption of nutrients such as fatty acids, amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52e79535cdc7193e2a0b53eec85c6fc
https://doi.org/10.1126/scisignal.abo7940
https://doi.org/10.1126/scisignal.abo7940
Autor:
Nadine Vollmuth, Lisa Schlicker, Yongxia Guo, Pargev Hovhannisyan, Sudha Janaki-Raman, Naziia Kurmasheva, Werner Schmitz, Almut Schulze, Kathrin Stelzner, Karthika Rajeeve, Thomas Rudel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db1b403004fba5226776f84c7978ed4e
https://doi.org/10.7554/elife.76721.sa2
https://doi.org/10.7554/elife.76721.sa2
Autor:
Nadine, Vollmuth, Lisa, Schlicker, Yongxia, Guo, Pargev, Hovhannisyan, Sudha, Janaki-Raman, Naziia, Kurmasheva, Werner, Schmitz, Almut, Schulze, Kathrin, Stelzner, Karthika, Rajeeve, Thomas, Rudel
Publikováno v:
eLife. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ee3dd72d8588fe700bacf78c56489c6
https://pubmed.ncbi.nlm.nih.gov/36155135
https://pubmed.ncbi.nlm.nih.gov/36155135
Autor:
Martin R. Jakobsen, Jean-Simon Diallo, Anne Louise Hansen, Taha Azad, Luc A. Sabourin, David Jacobs, Manja Idorn, Geneviève Laroche, Julien van Grevenynghe, Renée M. van der Sluis, Glib Maznyi, Jean Seguin, Fanghui Ren, Daniele Di Carlo, Rozanne Arulanandam, Ragunath Singaravelu, Kathy Fu, David Olagnier, Tommy Alain, Christian K. Holm, Søren R. Paludan, John C. Bell, Marceline Côté, John Hiscott, Demi van der Horst, Naziia Kurmasheva, Lena Cassin, Enrico Palermo, Madalina E. Carter-Timofte, Zaid Taha
Publikováno v:
ACS Infectious Diseases
Carter-Timofte, M E, Arulanandam, R, Kurmasheva, N, Fu, K, Laroche, G, Taha, Z, Van Der Horst, D, Cassin, L, Van Der Sluis, R M, Palermo, E, Di Carlo, D, Jacobs, D, Maznyi, G, Azad, T, Singaravelu, R, Ren, F, Hansen, A L, Idorn, M, Holm, C K, Jakobsen, M R, Van Grevenynghe, J, Hiscott, J, Paludan, S R, Bell, J C, Seguin, J, Sabourin, L A, Côté, M, Diallo, J S, Alain, T & Olagnier, D 2021, ' Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern ', ACS Infectious Diseases, vol. 7, no. 11, pp. 3034-3051 . https://doi.org/10.1021/acsinfecdis.1c00278
Carter-Timofte, M E, Arulanandam, R, Kurmasheva, N, Fu, K, Laroche, G, Taha, Z, Van Der Horst, D, Cassin, L, Van Der Sluis, R M, Palermo, E, Di Carlo, D, Jacobs, D, Maznyi, G, Azad, T, Singaravelu, R, Ren, F, Hansen, A L, Idorn, M, Holm, C K, Jakobsen, M R, Van Grevenynghe, J, Hiscott, J, Paludan, S R, Bell, J C, Seguin, J, Sabourin, L A, Côté, M, Diallo, J S, Alain, T & Olagnier, D 2021, ' Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern ', ACS Infectious Diseases, vol. 7, no. 11, pp. 3034-3051 . https://doi.org/10.1021/acsinfecdis.1c00278
The antimicrobial medication malarone (atovaquone/proguanil) is used as a fixed-dose combination for treating children and adults with uncomplicated malaria or as chemoprophylaxis for preventing malaria in travelers. It is an inexpensive, efficacious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd3972c1e417035d20e6f69542c6ca0
https://pubmed.ncbi.nlm.nih.gov/34658235
https://pubmed.ncbi.nlm.nih.gov/34658235
Autor:
Margarita R. Sharipova, Ayslu Mardanova, Tatyana Efremova, Naziia Kurmasheva, Vyacheslav Vorobiev
Publikováno v:
BioMed Research International, Vol 2018 (2018)
Providencia stuartiiis the most commonProvidenciaspecies capable of causing human infections. CurrentlyP. stuartiiis involved in high incidence of urinary tract infections in catheterized patients. The ability of bacteria to swarm on semisolid (visco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a65a2ba7c34c3c8b2e2f65d21901fd2
https://doi.org/10.1155/2018/3589135
https://doi.org/10.1155/2018/3589135