Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nazia Hilal"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
As binary switches, RAS proteins switch to an ON/OFF state during signaling and are on a leash under normal conditions. However, in RAS-related diseases such as cancer and RASopathies, mutations in the genes that regulate RAS signaling or the RAS its
Externí odkaz:
https://doaj.org/article/a58feaeb31e44f34958aea9b9160218d
Publikováno v:
Molecular Metabolism, Vol 47, Iss , Pp 101169- (2021)
Background: The global rise of metabolic disorders, such as obesity, type 2 diabetes, and cardiovascular disease, demands a thorough molecular understanding of the cellular mechanisms that govern health or disease. The endoplasmic reticulum (ER) is a
Externí odkaz:
https://doaj.org/article/9c5684cc5c84428799592281671579b2
Autor:
Sarah Araten, Ronald Mathieu, Anushka Jetly, Hoon Shin, Nazia Hilal, Bo Zhang, Katherine Morillo, Deepa Nandan, Indu Sivankutty, Ming Hui Chen, Sangita Choudhury
Publikováno v:
Journal of Molecular and Cellular Cardiology. 179:7-17
Single-cell approaches have become an increasingly popular way of understanding the genetic factors behind disease. Isolation of DNA and RNA from human tissues is necessary to analyze multi-omic data sets, providing information on the single-cell gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ebc7cb39650ec368a2c4e029683d7b
https://doi.org/10.1016/j.yjmcc.2023.03.010
https://doi.org/10.1016/j.yjmcc.2023.03.010
Autor:
Samirul Bashir, Mariam Banday, Ozaira Qadri, Debnath Pal, Arif Bashir, Nazia Hilal, Mohammad Altaf, Khalid Majid Fazili
Publikováno v:
FEBS Letters. 597:962-974
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88ecd424d61480aa84795ea7f83db61d
https://doi.org/10.1002/1873-3468.14593
https://doi.org/10.1002/1873-3468.14593
Autor:
Sangita Choudhury, August Yue Huang, Junho Kim, Zinan Zhou, Katherine Morillo, Eduardo A. Maury, Jessica W. Tsai, Michael B. Miller, Michael A. Lodato, Sarah Araten, Nazia Hilal, Eunjung Alice Lee, Ming Hui Chen, Christopher A. Walsh
Publikováno v:
Nature Aging. 2:714-725
The accumulation of somatic DNA mutations over time is a hallmark of aging in many dividing and nondividing cells but has not been studied in postmitotic human cardiomyocytes. Using single-cell whole-genome sequencing, we identified and characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31bdf78d75e273ff9d5821a56da4178
https://doi.org/10.1038/s43587-022-00261-5
https://doi.org/10.1038/s43587-022-00261-5
Publikováno v:
Journal of Drug Delivery and Therapeutics. 10:25-30
Background: Apoptosis is a normal physiological phenomenon that plays a pivotal role during embryonic development, retention of tissue homeostasis and pathology. The experimental investigation of apoptotic processes is still challenging and routinely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af7deba44343bd43af4f9c79cf4df1f9
https://doi.org/10.22270/jddt.v10i4.4124
https://doi.org/10.22270/jddt.v10i4.4124
ER is facilitated with a dynamic cellular pathway namely Unfolded Protein Response (UPR): an adaptive signalling mechanism that maintains proteostasis in response to ER stress. IRE1 is one of the three transmembrane sensors of UPR with dual protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb19d27636507f8fffa479eda4257e1b
https://doi.org/10.1101/2021.07.09.451832
https://doi.org/10.1101/2021.07.09.451832
BackgroundAquilegia nivalis Flax Jackson, also called Aquilegia vulgaris sub sp. nivalis (Bak.) Brühl or columbine, locally known as “Zoe-neel”, is a wild edible plant traditionally used as an anti-inflammatory medicine by the local nomadic trib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c661591acc1672b091409661940dd76
https://doi.org/10.21203/rs.3.rs-234542/v1
https://doi.org/10.21203/rs.3.rs-234542/v1
Autor:
Stephen D. Rader, Arif Bashir, Ozaira Qadri, Nazia Hilal, Khalid Majid Fazili, Nida-i-Fatima, Mariam Banday, Samirul Bashir
Publikováno v:
Life sciences. 265
The endoplasmic reticulum is primarily responsible for protein folding and maturation. However, the organelle is subject to varied stress conditions from time to time, which lead to the activation of a signaling program known as the Unfolded Protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77c13c1a15c48edd4a307df48a716b7
https://pubmed.ncbi.nlm.nih.gov/33188833
https://pubmed.ncbi.nlm.nih.gov/33188833
Autor:
Samirul Bashir, Debnath Pal, Mariam Banday, Ozaira Qadri, Arif Bashir, Younis Mohammad Hazari, Nazia Hilal, Mohammad Altaf, Khalid Majid Fazili
Unfolded protein response is a dynamic signalling pathway, which is involved in the maintenance of proteostasis and cellular homeostasis. IRE1, a transmembrane signalling protein represents the start point of a highly conserved UPR signalling cascade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d9e40e519d51a430085479cebf60c7