Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Nazareth Gengozian"'
Publikováno v:
Veterinary Immunology and Immunopathology. 121:161-168
Feline immunodeficiency virus (FIV) is an immunosuppressive lentivirus of domestic cats that serves as an animal model for the pathogenesis of CD4+ lymphopenia and thymus dysfunction in HIV infected humans. During most cases of adult and pediatric HI
Publikováno v:
Veterinary Immunology and Immunopathology. 108:253-264
The antibody produced by a murine hybridoma obtained from the fusion of SP2/0 plasmacytoma cells with splenocytes of a mouse immunized with feline bone marrow was found to react with 60% of bone marrow cells and 80% of peripheral blood leukocytes (PB
Publikováno v:
Experimental Biology and Medicine. 227:771-778
Rosette formation of feline peripheral blood leukocytes with guinea pig (GP) and gerbil (G) erythrocytes (E) has been shown in an earlier study to identify T lymphocytes expressing helper and suppressor cell activity, respectively. This T lymphocyte
Publikováno v:
Transplantation. 65:939-946
Background The current use of cord blood (CB) and peripheral blood (PB) stem cells as alternatives or adjunctives to bone marrow (BM) for hematopoietic reconstitution in the treatment of various diseases prompted an examination of the progenitors of
Autor:
Janet K. Yamamoto, Bruce L. Homer, Riuyu Pu, Leticia Reyes, Nazareth Gengozian, Francis J. Bova
Publikováno v:
Transplantation. 64:510-518
Feline bone marrow cells treated with the soybean agglutinin (SBA) lectin are separated into two populations, the agglutinated SBA(+) fraction containing predominantly cells of myeloid origin and the nonagglutinated SBA(-) fraction consisting of cell
Autor:
Nazareth Gengozian, Alfred M. Legendre
Publikováno v:
Transplantation. 60:836-840
Counterflow centrifugal elutriation (CCE) has been used to separate nucleated cells from mammalian bone marrow on the basis of size with the resultant isolation of hematopoietic cells in varying stages of lineage development. We examined the feasibil
Publikováno v:
Transplantation. 53:1313-1321
Lethally irradiated rhesus monkeys were treated with autologous bone marrow that had either been (1) nontreated, i.e., normal; (2) depleted of T lymphocytes with a monoclonal antibody directed against rhesus T lymphocytes; (3) fractionated with the s
Publikováno v:
Transplantation. 53:1306-1312
Three monoclonal antibodies directed against rhesus lymphocyte cell surface antigens are described. A pan-T mAb, T64, and a T suppressor mAb, T35, showed phenotypic and functional specificity for both human and rhesus cells. In contrast, a third mAb,
Publikováno v:
Proceedings of the National Academy of Sciences. 88:8435-8439
To study murine major histocompatibility complex (MHC)-haploidentical bone-marrow transplantation (BMT), B6C3F1 mice (H-2b/k) underwent BMT using syngeneic [B6C3F1 (H-2b/k)], haploidentical [CB6F1 (H-2d/b)], or fully allogeneic [DBA/2 (H-2d)] donor m
Publikováno v:
Veterinary immunology and immunopathology. 99(1-2)
The domestic cat is an excellent model for the development of therapeutic protocols that target hematopoietic stem cells (HSCs) because it is relatively resistant to complications related to bone marrow transplantation. To identify a plentiful source