Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Nazanin Tatari"'
Autor:
Nazanin Tatari, Xiaoyu Zhang, Shawn C. Chafe, Dillon McKenna, Keith A. Lawson, Minomi Subapanditha, Muhammad Vaseem Shaikh, Mathieu Seyfrid, Neil Savage, Chitra Venugopal, Jason Moffat, Sheila K. Singh
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Glioblastomas (GBM), the most common malignant primary adult brain tumors, are uniformly lethal and are in need of improved therapeutic modalities. GBM contain extensive regions of hypoxia and are enriched in therapy resistant brain tumor-initiating
Externí odkaz:
https://doaj.org/article/0954f30be233489fa8bd62d8a5099f88
Autor:
Branavan Manoranjan, Chitra Venugopal, David Bakhshinyan, Ashley A. Adile, Laura Richards, Michelle M. Kameda-Smith, Owen Whitley, Anna Dvorkin-Gheva, Minomi Subapanditha, Neil Savage, Nazanin Tatari, Dillon McKenna, Blessing Bassey-Archibong, Neil Winegarden, Robin Hallett, John P. Provias, Blake Yarascavitch, Olufemi Ajani, Adam Fleming, Gary D. Bader, Trevor J. Pugh, Bradley W. Doble, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The Wnt molecular subgroup of medulloblastoma is associated with better prognosis than the other molecular subgroups. Here, the authors show that activating Wnt signaling impairs tumor development and improves survival in Group 3 and Group 4 medullob
Externí odkaz:
https://doaj.org/article/90b86d3d0f9c41078f2e0a70337929d5
Autor:
Kevin Brown, Sheila Singh, Hong Han, Mathieu Seyfrid, William Thomas Maich, Vaseem Muhammad Shaikh, Nazanin Tatari, Deepak Upreti, Deween Piyasena, Minomi Subapanditha, Neil Savage, Dillon McKenna, Nicholas Mikolajewicz, Chirayu Chokshi, Laura Kuhlmann, Amanda Khoo, Sabra Khalid Salim, Blessing Archibong-Bassey, William Gwynne, Nadeem Murtaza, David Bakhshinyan, Parvez Vora, Chitra Venugopal, Jason Moffat, Thomas Kislinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/58fa9edb89474cc79d6aba282cfc533f
Autor:
Nazanin Tatari, William T. Maich, Sabra K. Salim, Dillon Mckenna, Chitra Venugopal, Sheila Singh
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100174- (2020)
Summary: Glioblastoma (GBM) is the most common malignant adult brain tumor that is resistant to the standard care therapy. Advances in chimeric antigen receptor (CAR) T cell therapies have spurred renewed interest in developing CAR T cell therapies t
Externí odkaz:
https://doaj.org/article/915efde6842243eb88b230ca0e0e28fc
Autor:
Margaret Stromecki, Nazanin Tatari, Ludivine Coudière Morrison, Ravinder Kaur, Jamie Zagozewski, Gareth Palidwor, Vijay Ramaswamy, Patryk Skowron, Matthias Wölfl, Till Milde, Marc R. Del Bigio, Michael D. Taylor, Tamra E. Werbowetski‐Ogilvie
Publikováno v:
Molecular Oncology, Vol 12, Iss 4, Pp 495-513 (2018)
Medulloblastoma (MB) is the most common malignant primary pediatric brain cancer. Among the most aggressive subtypes, Group 3 and Group 4 originate from stem/progenitor cells, frequently metastasize, and often display the worst prognosis, yet we know
Externí odkaz:
https://doaj.org/article/7bf98c7755da4eec9545cf267075d874
Autor:
Vincent Huynh, Nazanin Tatari, April Marple, Neil Savage, Dillon McKenna, Chitra Venugopal, Sheila K. Singh, Ryan Wylie
Publikováno v:
Journal of Controlled Release. 348:386-396
Many protein immunotherapeutics are hindered by transport barriers that prevent the obtainment of minimum effective concentrations (MECs) in solid tumors. Local delivery vehicles with tunable release (infusion) rates for immunotherapeutics are being
Autor:
Blessing Iquo Bassey-Archibong, Chirayu Rajendra Chokshi, Nikoo Aghaei, Agata Monika Kieliszek, Nazanin Tatari, Dillon McKenna, Mohini Singh, Minomi Kalpana Subapanditha, Arun Parmar, Daniel Mobilio, Neil Savage, Fred Lam, Tomas Tokar, John Provias, Yu Lu, Shawn Christopher Chafe, Charles Swanton, Robert Edward Hynds, Chitra Venugopal, Sheila Kumari Singh
Brain metastases (BM) are the most common brain neoplasm in adults. Current BM therapies still offer limited efficacy and reduced survival outcomes, emphasizing the need for a better understanding of the disease. Herein, we analyzed the transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f688de303b5131216db099f4c299e47
Autor:
Philip Schmassmann, Julien Roux, Alicia Buck, Nazanin Tatari, Sabrina Hogan, Jinyu Wang, Sohyon Lee, Berend Snijder, Tomás A. Martins, Marie-Françoise Ritz, Tala Shekarian, Deniz Kaymak, Marta McDaid, Michael Weller, Tobias Weiss, Heinz Läubli, Gregor Hutter
Glioblastoma (GBM) is the most aggressive form of primary brain tumor, for which effective therapies are urgently needed. Cancer cells are capable of evading clearance by phagocytes such as microglia and monocyte-derived cells through engaging tolero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f7f03a9766036181787672ae1c5154a
https://doi.org/10.1101/2022.11.07.515406
https://doi.org/10.1101/2022.11.07.515406
Autor:
Neil Savage, Franz Zemp, Nick Mikolajewicz, Hong Han, Chitra Venugopal, Chirayu Chokshi, Nazanin Tatari, Thomas Kislinger, Jason Moffat, Doug Mahoney, Sheila Singh
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Nazanin Tatari, Shahbaz Khan, Julie Livingstone, Kui Zhai, Dillon Mckenna, Vladimir Ignatchenko, Chirayu Chokshi, William D. Gwynne, Manoj Singh, Spencer Revill, Nicholas Mikolajewicz, Chenghao Zhu, Jennifer Chan, Cynthia Hawkins, Jian-Qiang Lu, John P. Provias, Kjetil Ask, Sorana Morrissy, Samuel Brown, Tobias Weiss, Michael Weller, Hong Han, Jeffrey N. Greenspoon, Jason Moffat, Chitra Venugopal, Paul C. Boutros, Sheila K. Singh, Thomas Kislinger
Publikováno v:
Acta Neuropathol
Acta neuropathologica, vol 144, iss 6
Acta neuropathologica, vol 144, iss 6
Glioblastoma (GBM) is characterized by extensive cellular and genetic heterogeneity. Its initial presentation as primary disease (pGBM) has been subject to exhaustive molecular and cellular profiling. By contrast, our understanding of how GBM evolves