Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nazanin, Rohani"'
Autor:
Bassel Akache, Tyler M. Renner, Matthew Stuible, Nazanin Rohani, Yuneivy Cepero-Donates, Lise Deschatelets, Renu Dudani, Blair A. Harrison, Christian Gervais, Jennifer J. Hill, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Anne E. G. Lenferink, Yves Durocher, Michael J. McCluskie
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-7 (2022)
Abstract Using our strongly immunogenic SmT1 SARS-CoV-2 spike antigen platform, we developed antigens based on the Beta & Delta variants of concern (VOC). These antigens elicited higher neutralizing antibody activity to the corresponding variant than
Externí odkaz:
https://doaj.org/article/d6403fda9ca74d4599cc113bbc9a49d9
Autor:
Tyler M. Renner, Bassel Akache, Matthew Stuible, Nazanin Rohani, Yuneivy Cepero-Donates, Lise Deschatelets, Renu Dudani, Blair A. Harrison, Jason Baardsnes, Izel Koyuturk, Jennifer J. Hill, Usha D. Hemraz, Sophie Régnier, Anne E. G. Lenferink, Yves Durocher, Michael J. McCluskie
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Liposomes composed of sulfated lactosyl archaeol (SLA) have been shown to be a safe and effective vaccine adjuvant with a multitude of antigens in preclinical studies. In particular, SLA-adjuvanted SARS-CoV-2 subunit vaccines based on trimeric spike
Externí odkaz:
https://doaj.org/article/7fefd380ab0e4f5e85bdc7345e2dcf2c
Autor:
Traian Sulea, Jason Baardsnes, Matthew Stuible, Nazanin Rohani, Anh Tran, Marie Parat, Yuneivy Cepero Donates, Mélanie Duchesne, Pierre Plante, Guneet Kour, Yves Durocher
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0266250 (2022)
The SARS coronavirus 2 (SARS-CoV-2) spike (S) protein binding to the human ACE2 receptor is the molecular event that initiates viral entry into host cells and leads to infection and virus replication. There is a need for agents blocking viral entry i
Externí odkaz:
https://doaj.org/article/8b6eba9df05d411880bdd994868f66fa
Autor:
Traian Sulea, Nazanin Rohani, Jason Baardsnes, Christopher R. Corbeil, Christophe Deprez, Yuneivy Cepero-Donates, Alma Robert, Joseph D. Schrag, Marie Parat, Mélanie Duchesne, Maria L. Jaramillo, Enrico O. Purisima, John C. Zwaagstra
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Recent development of monoclonal antibodies as mainstream anticancer agents demands further optimization of their safety for use in humans. Potent targeting and/or effector activities on normal tissues is an obvious toxicity concern. Optimization of
Externí odkaz:
https://doaj.org/article/f7e7bbaa010a45d39cfc5376757156e7
Autor:
Frank B. Gertler, Sangeeta N. Bhatia, Christopher B. Burge, Michael B. Yaffe, Douglas A. Lauffenburger, Anthony R. Soltis, Mira N. Moufarrej, Konstantin Krismer, Brian A. Joughin, Maria S. Alexis, Liangliang Hao, Nazanin Rohani
Figure S3 shows CA9 localization relative to markers for cell invasion and proliferation in human IDC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503e373ce29e48161318bcff4ce97f08
https://doi.org/10.1158/0008-5472.22423761
https://doi.org/10.1158/0008-5472.22423761
Autor:
Frank B. Gertler, Olivia J. Kelada, Emilia M Pulver, Sangeeta N. Bhatia, Henry Ko, Heather E. Fleming, Renee T. Zhao, Nazanin Rohani, Liangliang Hao, Howard Mak
Publikováno v:
Nature Materials. 20:1440-1448
Therapeutic outcomes in oncology may be aided by precision diagnostics that offer early detection, localization and the opportunity to monitor response to therapy. Here, we report a multimodal nanosensor engineered to target tumours through acidosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0514389bf5880fadb3562097c6f3e84b
https://doi.org/10.1038/s41563-021-01042-y
https://doi.org/10.1038/s41563-021-01042-y
Publikováno v:
PLoS Biology, Vol 12, Iss 9, p e1001955 (2014)
Ephrins and Eph receptors are involved in the establishment of vertebrate tissue boundaries. The complexity of the system is puzzling, however in many instances, tissues express multiple ephrins and Ephs on both sides of the boundary, a situation tha
Externí odkaz:
https://doaj.org/article/b2ef38711e73473db14e90025c6a6177
Publikováno v:
Cancer Research. 82:B041-B041
The drug discovery process in oncology relies mainly on screening and preclinical validation platforms that use human cancer cells that are grown in standard monolayer (2D) cultures. However, 2D monolayer cell culture methods poorly reflect the tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b06b1387b46e5d36b279bdfce7fec506
https://doi.org/10.1158/1538-7445.evodyn22-b041
https://doi.org/10.1158/1538-7445.evodyn22-b041
Publikováno v:
PLoS Biology, Vol 9, Iss 3, p e1000597 (2011)
BackgroundThe primordial organization of the metazoan body is achieved during gastrulation by the establishment of the germ layers. Adhesion differences between ectoderm, mesoderm, and endoderm cells could in principle be sufficient to maintain germ
Externí odkaz:
https://doaj.org/article/f425740e81d6470aa9b67d5d791af3d0
Autor:
Yuneivy Cepero-Donates, Maria L. Jaramillo, Nazanin Rohani, Marie Parat, Joseph D. Schrag, Christophe Deprez, Christopher R. Corbeil, Alma Robert, Jason Baardsnes, Traian Sulea, Mélanie Duchesne, Enrico O. Purisima, John C. Zwaagstra
Publikováno v:
mAbs
Recent development of monoclonal antibodies as mainstream anticancer agents demands further optimization of their safety for use in humans. Potent targeting and/or effector activities on normal tissues is an obvious toxicity concern. Optimization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a669f3e9903baa91ccd54cdf4304f7d
https://doi.org/10.1080/19420862.2019.1682866
https://doi.org/10.1080/19420862.2019.1682866