Výsledky vyhledávání - "Nayu, Mitomi"

Population Pharmacokinetics of Tebipenem Pivoxil (ME1211), a Novel Oral Carbapenem Antibiotic, in Pediatric Patients with Otolaryngological Infection or Pneumonia

Autor: Hiroyuki Hayashi, Tohru Kurosawa, Shigeki Shibasaki, Kyoichi Totsuka, Nayu Mitomi, Jun Morita, Tomokazu Koresawa, Koji Kijima, Hisashi Suzuki, Nobuo Sato

Publikováno v: Drug Metabolism and Pharmacokinetics. 23:434-446

Tebipenem pivoxil (TBPM-PI, ME1211) has been under development as the world's first oral carbapenem for treatment of otolaryngological/respiratory infections caused by drug-resistant S. pneumoniae in pediatric patients. In order to treat these infect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7167e629a8ef1c6f95f2a91f451959a9
https://doi.org/10.2133/dmpk.23.434

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Protective Effect of Inactive Ingredients against Nephrotoxicity of Vancomycin Hydrochloride in Rats

Autor: Shigeki Shibasaki, Yoshihisa Nakano, Nayu Mitomi, Akiko Gyobu, Naoko Hodoshima, Masaaki Izumi, Toru Kurosawa, Yukari Nakamura, Makoto Aoki

Publikováno v: Drug Metabolism and Pharmacokinetics. 19:68-75

A generic form of vancomycin for I.V. infusion (MEEK) is more soluble and stable than the brand-name form of vancomycin hydrochloride (VCM) due to the addition of two inactive ingredients: D-mannitol and Macrogol400 (PEG400). The aim of the present s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93191c38e55d156510922c78aad6e5d
https://doi.org/10.2133/dmpk.19.68

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Population pharmacokinetics of cefditoren pivoxil in non-infected adults

Autor: Kayoko, Matsumoto, Nobuo, Sato, Nayu, Mitomi, Yoshihisa, Shitara, Shigeki, Shibasaki

Publikováno v: The Japanese journal of antibiotics. 67(1)

Population pharmacokinetic analysis was conducted on cefditoren pivoxil (CDTR-PI), a third generation oral antibiotic to evaluate the effect of covariates on pharmacokinetic parameters. Plasma concentrations of cefditoren (CDTR, total number of sampl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::58e74640298efa6e1afb859b5d562378
https://pubmed.ncbi.nlm.nih.gov/24809208

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Population pharmacokinetic analysis of cefditoren pivoxil in pediatric patients with infection

Autor: Kayoko, Matsumoto, Nobuo, Sato, Nayu, Mitomi, Shigeki, Shibasaki

Publikováno v: The Japanese journal of antibiotics. 66(6)

Population pharmacokinetic analysis was conducted on cefditoren pivoxil (CDTR-PI, Brand name: MEIACT, Meiji Seika Pharma Co., Ltd.), a third generation oral antibiotic, using plasma concentrations of cefditoren (CDTR, total number of sampling points:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d767ee1ce54710143a906b15b230558
https://pubmed.ncbi.nlm.nih.gov/24649799

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Toxicokinetic approach for evaluating respiratory depression effect of aminoglycoside antibiotics: Species differences in drug susceptibility

Autor: Hiromi Takata, Takashi Kuribayashi, Izumi Komiya, Nayu Mitomi

Publikováno v: Biopharmaceutics & Drug Disposition. 14:443-454

The respiratory depression effect of aminoglycoside antibiotics was studied by a toxicokinetic approach, and species differences in drug susceptibility were elucidated based on plasma concentrations. An allometric relationship was obtained between to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a6e6f1aeb22a54640c02e7b10181bf
https://doi.org/10.1002/bdd.2510140510

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