Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nayna Sanathara"'
Autor:
Joseph Phan, Lamees Alhassen, Allan Argelagos, Wedad Alhassen, Benjamin Vachirakorntong, Zitong Lin, Nayna Sanathara, Amal Alachkar
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract The two hypothalamic neuropeptides oxytocin and melanin concentrating hormone (MCH) share several physiological actions such as the control of maternal care, sexual behavior, and emotions. In this study, we uncover the role for the oxytocin-
Externí odkaz:
https://doaj.org/article/b39fd5a2ec4c48449b184247be55149d
Autor:
Nayna Sanathara, Olivier Civelli, Lamees Alhassen, Alice Lo, Wedad Alhassen, Paul Nguyen, Amal Alachkar, Alvin Phan, Hanan Shaharuddin
Publikováno v:
Brain Research. 1719:71-76
Melanin concentrating hormone (MCH) is involved in the initiation of maternal behavior during the postpartum period. Virgin females also display some aspects of maternal care independent of the hormonal and neurochemical changes associated with pregn
Autor:
Qi Dai, Abdul Rezzak Hamzeh, Marquis P. Vawter, Nayna Sanathara, Lamees Alhassen, Lucas Pauluk, Jasmine Sakr, Amal Alachkar, Xuejie Wang, Ryan F. Yoshimura, Olivier Civelli, Anton Schulmann, Wedad Alhassen
Publikováno v:
International Journal of Neuropsychopharmacology
The international journal of neuropsychopharmacology, vol 23, iss 1
The international journal of neuropsychopharmacology, vol 23, iss 1
Background Evidence from anatomical, pharmacological, and genetic studies supports a role for the neuropeptide melanin concentrating hormone (MCH) system in modulating emotional and cognitive functions. Genome wide association (GWA) studies revealed
Autor:
Benjamin Vachirakorntong, Lamees Alhassen, Zitong Lin, Allan Argelagos, Wedad Alhassen, Joseph Phan, Nayna Sanathara, Amal Alachkar
Publikováno v:
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
The two hypothalamic neuropeptides oxytocin and melanin concentrating hormone (MCH) share several physiological actions such as the control of maternal care, sexual behavior, and emotions. In this study, we uncover the role for the oxytocin-MCH signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c823fadf0b8b436b5551b31d4535ebcd
https://escholarship.org/uc/item/4rb1s06b
https://escholarship.org/uc/item/4rb1s06b
Autor:
Amal Alachkar, Wedad Alhassen, Ilias Marmouzi, Nayna Sanathara, Mohammad Khoudari, Olivier Civelli, Joseph Phan, Lamees Alhassen
Publikováno v:
Neuropharmacology. 184:108423
Oxytocin regulates social behaviors and has been linked to the etiology of autism and schizophrenia. Oxytocin and another hypothalamic neuropeptide, melanin concentrating hormone (MCH), share several physiological actions such as emotion, social beha
Autor:
A R Hamzeh, Nayna Sanathara, S M Lee, Zitong Wang, Ryan F. Yoshimura, Xiangmin Xu, Lien Wang, Amal Alachkar, Olivier Civelli, Geoffrey W. Abbott
Publikováno v:
Alachkar, A; Wang, L; Yoshimura, R; Hamzeh, AR; Wang, Z; Sanathara, N; et al.(2018). Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits. MOLECULAR PSYCHIATRY, 23(2), 282-294. doi: 10.1038/mp.2017.164. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2wh1n4k9
Molecular psychiatry, vol 23, iss 2
Molecular psychiatry, vol 23, iss 2
The methionine-folate cycle-dependent one-carbon metabolism is implicated in the pathophysiology of schizophrenia. Since schizophrenia is a developmental disorder, we examined the effects that perturbation of the one-carbon metabolism during gestatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34883ca02ede05224f5dfe4db088d13c
http://www.escholarship.org/uc/item/2wh1n4k9
http://www.escholarship.org/uc/item/2wh1n4k9
Autor:
Zhiwei Wang, Olivier Civelli, Katsuhiko Nishimori, Lien Wang, Amal Alachkar, Xiangmin Xu, Nayna Sanathara, Celia Garau
Publikováno v:
Neuropharmacology. 128
Repetitive and perseverative behaviors are common features of a number of neuropsychiatric diseases such as Angelman’s syndrome, Tourette’s syndrome, obsessive-compulsive disorder, and autism spectrum disorders. The oxytocin system has been linke
Autor:
Kara Onouye, Lamees Alhassen, Amal Alachkar, Olivier Civelli, Zhiwei Wang, Lien Wang, Nayna Sanathara
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, vol 26, iss 11
Alachkar, A; Alhassen, L; Wang, Z; Wang, L; Onouye, K; Sanathara, N; et al.(2016). Inactivation of the melanin concentrating hormone system impairs maternal behavior. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 26(11), 1826-1835. doi: 10.1016/j.euroneuro.2016.08.014. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5sf1n5tc
Alachkar, A; Alhassen, L; Wang, Z; Wang, L; Onouye, K; Sanathara, N; et al.(2016). Inactivation of the melanin concentrating hormone system impairs maternal behavior. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 26(11), 1826-1835. doi: 10.1016/j.euroneuro.2016.08.014. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5sf1n5tc
In order to prepare the mother for the demands of pregnancy and lactation, the maternal brain is subjected to a number of adaptations. Maternal behaviors are regulated by complex neuronal interactions. Here, we show that the melanin concentrating hor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602c9afbbce8c47805a7207bedaf8298
https://escholarship.org/uc/item/5sf1n5tc
https://escholarship.org/uc/item/5sf1n5tc
Publikováno v:
Hormones and Behavior. 60:540-548
Sexual receptivity, lordosis, can be induced by sequential estradiol and progesterone or extended exposure to high levels of estradiol in the female rat. In both cases estradiol initially inhibits lordosis through activation of β-endorphin (β-END)
Publikováno v:
The international journal of neuropsychopharmacology, vol 18, iss 12
International Journal of Neuropsychopharmacology
Wang, L; Alachkar, A; Sanathara, N; Belluzzi, JD; Wang, Z; & Civelli, O. (2015). A Methionine-Induced Animal Model of Schizophrenia: Face and Predictive Validity. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 18(12). doi: 10.1093/ijnp/pyv054. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/45m6s3qq
International Journal of Neuropsychopharmacology
Wang, L; Alachkar, A; Sanathara, N; Belluzzi, JD; Wang, Z; & Civelli, O. (2015). A Methionine-Induced Animal Model of Schizophrenia: Face and Predictive Validity. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 18(12). doi: 10.1093/ijnp/pyv054. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/45m6s3qq
Background: Modulating the methylation process induces broad biochemical changes, some of which may be involved in schizophrenia. Methylation is in particular central to epigenesis, which is also recognized as a factor in the etiology of schizophreni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0175bbddbd6e613134687b1124f54f52
https://escholarship.org/uc/item/45m6s3qq
https://escholarship.org/uc/item/45m6s3qq