Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus

Autor: Katy Poncin, Agnès Roba, Ravikumar Jimmidi, Georges Potemberg, Antonella Fioravanti, Nayla Francis, Kévin Willemart, Nicolas Zeippen, Arnaud Machelart, Emanuele G. Biondi, Eric Muraille, Stéphane P. Vincent, Xavier De Bolle

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

It is assumed that intracellular pathogenic bacteria must cope with DNA alkylating stress within host cells. Here, Poncin et al. show that the pathogen Brucella abortus does encounter alkylating stress within macrophages, and shed light into the path

Externí odkaz: https://doaj.org/article/0e9cb03fdb914652b78daf4b8a72caac

Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus

Autor: Xavier De Bolle, Arnaud Machelart, Katy Poncin, Eric Muraille, Emanuele G. Biondi, Nayla Francis, Agnès Roba, Kevin Willemart, Nicolas Zeippen, Georges Potemberg, Antonella Fioravanti, Stéphane P. Vincent, Ravikumar Jimmidi

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-12516-8⟩
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-12516-8⟩
Poncin, K, Roba, A, Jimmidi, R, Potemberg, G, Fioravanti, A, Francis, N, Willemart, K, Zeippen, N, Machelart, A, Biondi, E G, Muraille, E, Vincent, S P & De Bolle, X 2019, ' Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus ', Nature Communications, vol. 10, no. 1, 4847, pp. 4847 . https://doi.org/10.1038/s41467-019-12516-8
Nature communications, 10 (1
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

It is assumed that intracellular pathogenic bacteria have to cope with DNA alkylating stress within host cells. Here we use single-cell reporter systems to show that the pathogen Brucella abortus does encounter alkylating stress during the first hour

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1d24f7e59a59df9acf427e3b9dd9bd
https://biblio.vub.ac.be/vubir/occurrence-and-repair-of-alkylating-stress-in-the-intracellular-pathogen-brucella-abortus(32eb28a2-69fe-4808-870b-f7c0710f221e).html

Transposon Sequencing of Brucella abortus Uncovers Essential Genes for Growth In Vitro and Inside Macrophages

Autor: Mathilde Van der Henst, Jean-François Sternon, Beat Christen, Xavier De Bolle, Katy Poncin, Pierre Godessart, Jean-Jacques Letesson, Nayla Francis, Kevin Willemart, Matthias Christen, Rosa Gonçalves de Freitas

Publikováno v: Infection and Immunity. 86

Brucella abortus is a class III zoonotic bacterial pathogen able to survive and replicate inside host cells, including macrophages. Here we report a multidimensional transposon sequencing analysis to identify genes essential for Brucella abortus grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb2f5a0e72323205526303fd60e3e712
https://doi.org/10.1128/iai.00312-18

CtrA controls cell division and outer membrane composition of the pathogen Brucella abortus

Autor: Nayla, Francis, Katy, Poncin, Antonella, Fioravanti, Victoria, Vassen, Kevin, Willemart, Thi Anh Phuong, Ong, Luca, Rappez, Jean-Jacques, Letesson, Emanuele G, Biondi, Xavier, De Bolle

Publikováno v: Molecular microbiology. 103(5)

Brucella abortus is a pathogen infecting cattle, able to survive, traffic, and proliferate inside host cells. It belongs to the Alphaproteobacteria, a phylogenetic group comprising bacteria with free living, symbiotic, and pathogenic lifestyles. An e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::41122c589b5385905cde2091eb6a8bdd
https://pubmed.ncbi.nlm.nih.gov/27893179