Zobrazeno 1 - 10 of 103 pro vyhledávání: '"Nayara I Viana"'
1
Akademický článek
BCG downregulates PD1 and PD-L1 expression in bladder cancer cells co-cultivated with peripheral blood mononuclear cells
Autor: Katia R. M. Leite, Denis Reis Morais, Cristina Massoco, Sabrina T. Reis, Nayara I. Viana, Iran A. Silva, Vanessa Guimaraes, Ruan Pimenta, Gabriel Arantes, Miguel Srougi, Willian Carlos Nahas
Publikováno v: Surgical and Experimental Pathology, Vol 5, Iss 1, Pp 1-5 (2022)
Abstract Purpose BCG is the standard of care to treat high risk non-muscle invasive bladder cancer (NMIBC), reducing recurrence. PD-L1 is a ligand of the co-inhibitory receptor PD1 that has been shown to be expressed by tumor cells of distinct origin
Externí odkaz: https://doaj.org/article/eb4bd3001dcf448a9dfbf64bd51ead04
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2
Akademický článek
Shorter leukocyte telomere length is associated with severity of COVID-19 infection.
Autor: Gabriel Arantes dos Santos, Ruan Pimenta, Nayara I. Viana, Vanessa R. Guimarães, Poliana Romão, Patrícia Candido, Juliana A. de Camargo, Diná M. Hatanaka, Paula GS. Queiroz, Alexandre Teruya, Katia R.M. Leite, Victor Srougi, Miguel Srougi, Sabrina T. Reis
Publikováno v: Biochemistry and Biophysics Reports, Vol 27, Iss , Pp 101056- (2021)
The infection by COVID-19 is a serious global public health problem. An efficient way to improve this disease's clinical management would be to characterize patients at higher risk of progressing to critically severe infection using prognostic biomar
Externí odkaz: https://doaj.org/article/85d47a6a7bf54937ab2a91903eacf7e7
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3
Akademický článek
Circulating miR-34a and Bone Mineral Density of Brazilian Very-Old Adults
Autor: Otávio T. Nóbrega, Gilberto S. Morais-Junior, Nayara I. Viana, Sabrina T. Reis, Diego I. V. Perez, Wladimir M. Freitas, Andrei C. Sposito, Kátia R. M. Leite, Miguel Srougi
Publikováno v: Journal of Aging Research, Vol 2020 (2020)
The human aging is marked by several body changes, including in bone mineral density (BMD). Research shows that microRNAs are important modulators of bone metabolism. The present research aims to analyze the whole blood concentration of 10 selected m
Externí odkaz: https://doaj.org/article/1449c0e771244d85bbb126e34029bfff
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4
Akademický článek
miR-618: possible control over TIMP-1 and its expression in localized prostate cancer
Autor: Renato F. Ivanovic, Nayara I. Viana, Denis R. Morais, Caio Moura, Iran A. Silva, Katia R. Leite, José Pontes-Junior, William C. Nahas, Miguel Srougi, Sabrina T. Reis
Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-6 (2018)
Abstract Background The imbalance between the action of the tissue inhibitors of matrix metalloproteinases (TIMPs) and the matrix metalloproteinases (MMPs) is one component of metastasis physiology. TIMP-1 overrides MMP-9 activity in cancer and might
Externí odkaz: https://doaj.org/article/0a79409e59c441e5a291225142fc6cce
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5
Akademický článek
miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression
Autor: Renato F. Ivanovic, Nayara I. Viana, Denis R. Morais, Iran A. Silva, Katia R. Leite, José Pontes-Junior, Gustavo Inoue, William C. Nahas, Miguel Srougi, Sabrina T. Reis
Publikováno v: Cancer Cell International, Vol 18, Iss 1, Pp 1-6 (2018)
Abstract Background The ability to metastasize is one of the most important characteristics of neoplastic cells. An imbalance between the action of some matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs drives the invasion process. Some
Externí odkaz: https://doaj.org/article/f29b204ea35a4da293b4d83dcfe18953
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6
Intratumoral Restoration of miR-137 Plus Cholesterol Favors Homeostasis of the miR-137/Coactivator p160/AR Axis and Negatively Modulates Tumor Progression in Advanced Prostate Cancer
Autor: Reis, Ruan Pimenta, Carolina Mie Mioshi, Guilherme L. Gonçalves, Patrícia Candido, Juliana A. Camargo, Vanessa R. Guimarães, Caroline Chiovatto, Vitória Ghazarian, Poliana Romão, Karina Serafim da Silva, Gabriel A. dos Santos, Iran A. Silva, Miguel Srougi, William C. Nahas, Kátia R. Leite, Nayara I. Viana, Sabrina T.
Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9633
MicroRNAs (miRNAs) have gained a prominent role as biomarkers in prostate cancer (PCa). Our study aimed to evaluate the potential suppressive effect of miR-137 in a model of advanced PCa with and without diet-induced hypercholesterolemia. In vitro, P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::c048f99822988ba0a08b35b87c4539f9
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7
Pan-cancer analysis reveals that CTC1-STN1-TEN1 (CST) complex may have a key position in oncology
Autor: Gabriel Arantes dos Santos, Nayara I. Viana, Ruan Pimenta, Juliana Alves de Camargo, Vanessa R. Guimaraes, Poliana Romão, Patrícia Candido, Vitória Ghazarian, Sabrina T. Reis, Katia Ramos Moreira Leite, Miguel Srougi
Publikováno v: Cancer Genetics. :80-90
Telomere dysfunction is one of the hallmarks of cancer, which puts telomere-associated genes in a prominent position in oncology. The CTC1-STN1-TEN1 (CST) complex is vital for telomere maintenance and participates in several steps of DNA metabolism,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da3449c2ccfb993ef36bd857d68bb0f
https://doi.org/10.1016/j.cancergen.2022.01.006
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8
Akademický článek
MicroRNA-23b and microRNA-27b plus flutamide treatment enhances apoptosis rate and decreases CCNG1 expression in a castration-resistant prostate cancer cell line
Autor: Ruan CA Pimenta, Nayara I Viana, Gabriela Q Amaral, Rubens Park, Denis R Morais, José Pontes, Vanessa R Guimaraes, Juliana A Camargo, Kátia RM Leite, William C Nahas, Miguel Srougi, Sabrina T Reis
Publikováno v: Tumor Biology, Vol 40 (2018)
The acquisition of a castration-resistant prostate cancer phenotype by prostate cancer cells is the alteration that has the worst prognosis for patients. The aim of this study was to evaluate the role of the microRNAs-23b/-27b as well as the possible
Externí odkaz: https://doaj.org/article/e676d50aea5941f4a31fb6e537849a9f
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9
Can increased expression of miR-Let-7c reduce the transition potential of high-grade urothelial carcinoma?
Autor: Miguel Srougi, Sabrina T. Reis, Ruan Pimenta, Iran A. Silva, William C. Nahas, Vitória Ghazarian, Poliana Romão, Katia R. M. Leite, Nayara I. Viana, Paulo Ricardo da Silva Gomes, Patrícia Candido, Vanessa Ribeiro Guimarães, Juliana de Souza Almeida Aranha Camargo, Guilherme Lopes Gonçalves
Publikováno v: Molecular Biology Reports. 48:7947-7952
BACKGROUND Bladder cancer is the leading transitional cell carcinoma affecting men and women with high morbidity and mortality rates, justifying the need to develop new molecular target therapies using microRNAs. This study aimed to evaluate the beha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a4f0a2312282ed35d4b162198bd7dcb
https://doi.org/10.1007/s11033-021-06825-9
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10
Podemos usar a expressão de Ki67 para prever a agressividade do câncer de próstata?
Autor: RONALDO MAIA, GABRIEL ARANTES DOS SANTOS, SABRINA REIS, NAYARA I VIANA, RUAN PIMENTA, VANESSA R GUIMARÃES, SAULO RECUERO, POLIANA ROMÃO, KATIA RAMOS MOREIRA LEITE, MIGUEL SROUGI, CARLO CARMARGO PASSEROTTI
Publikováno v: Revista do Colégio Brasileiro de Cirurgiões, Volume: 49, Article number: e20223200, Published: 01 JUL 2022
Revista do Colégio Brasileiro de Cirurgiões v.49 2022
Revista do Colégio Brasileiro de Cirurgiões
Colégio Brasileiro de Cirurgiões (CBC)
instacron:CBC
Introduction: specialists have an urge for biomarkers that can discriminate indolent prostate cancer from aggressive tumors. Ki67 is a proliferation marker, and its expression is associated with the aggressiveness of several cancers. Objective: analy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3aabcda7f5994459b31b2dcc00d8ac1
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912022000100220&lng=en&tlng=en
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