Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nayanthara U. Dharmaratne"'
Publikováno v:
Cells, Vol 10, Iss 3, p 541 (2021)
The delivery of cancer therapeutics can be limited by pharmacological issues such as poor bioavailability and high toxicity to healthy tissue. pH-low insertion peptides (pHLIPs) represent a promising tool to overcome these limitations. pHLIPs allow f
Externí odkaz:
https://doaj.org/article/3589d1284a0b4945b59c6d6ba0fb57bc
Autor:
Matthew K. Kiesewetter, Nayanthara U. Dharmaratne, Oleg I. Kazakov, Timothy J. Bannin, Jinal U. Pothupitiya
Publikováno v:
ACS macro letters. 6(4)
The antibacterial compound, triclocarban (TCC), is shown to be a highly effective H-bond donating catalyst for ring-opening polymerization (ROP) when applied with an H-bond accepting base cocatalyst. These ROPs exhibit the characteristics of “livin
Autor:
Elizabeth T. Kiesewetter, Rukshika S. Hewawasam, U. L. D. Inush Kalana, Timothy J. Bannin, Nayanthara U. Dharmaratne, Thomas J. Wright, Matthew K. Kiesewetter
Publikováno v:
Macromolecules. 52:9232-9237
A series of conformationally flexible bis(thio)urea H-bond donors plus base cocatalyst were applied to the ring-opening polymerization (ROP) of lactones. The rate of the ROP displays a strong depen...
Autor:
Matthew K. Kiesewetter, Kurt V. Fastnacht, Danielle N. Coderre, Thomas J. Wright, Nayanthara U. Dharmaratne
Publikováno v:
Macromolecules. 51:10121-10126
The ring-opening polymerization (ROP) kinetics of e-caprolactone and lactide with various H-bonding organocatalysts, (thio)ureas paired with an amine cocatalyst, were evaluated at temperatures up to 110 °C. In nonpolar solvent, most cocatalyst syste
Publikováno v:
Macromolecules. 51:8461-8468
A combined experimental and computational investigation revealed a hydrophobicity trend for oxygen-containing functional groups commonly encountered in monomers and polymers. Based on solvatochroma...
Autor:
Matthew K. Kiesewetter, Nayanthara U. Dharmaratne, Danielle N. Coderre, Jinal U. Pothupitiya, Kurt V. Fastnacht, Terra Marie M. Jouaneh
Publikováno v:
Macromolecules. 50:8948-8954
The developing urea class of H-bond donors facilitates the solvent-free ROP of lactones at ambient and elevated temperatures, displaying enhanced rates and control versus other known organocatalysts for ROP under solvent-free conditions. The ROPs ret
Publikováno v:
Organicbiomolecular chemistry. 17(13)
Among the various catalysts for ROP, H-bonding organocatalysts stand out in the precise level of reaction control they are able to render during ROP. The H-bonding class of organocatalysts are thought to effect ROP via dual activation of both monomer
Autor:
Matthew K. Kiesewetter, Jinal U. Pothupitiya, Elizabeth T. Kiesewetter, Partha P. Datta, Kurt V. Fastnacht, Nayanthara U. Dharmaratne, Samuel S. Spink
Publikováno v:
ACS Macro Letters. 5:982-986
A new class of H-bond donating ureas was developed for the ring-opening polymerization (ROP) of lactone monomers, and they exhibit dramatic rate acceleration versus previous H-bond mediated polymerization catalysts. The most active of these new catal