Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nawat Bunnag"'
Autor:
Chen Shen, Anmada Nayak, Leif R. Neitzel, Amber A. Adams, Maya Silver-Isenstadt, Leah M. Sawyer, Hassina Benchabane, Huilan Wang, Nawat Bunnag, Bin Li, Daniel T. Wynn, Fan Yang, Marta Garcia-Contreras, Charles H. Williams, Sivanesan Dakshanamurthy, Charles C. Hong, Nagi G. Ayad, Anthony J. Capobianco, Yashi Ahmed, Ethan Lee, David J. Robbins
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Cereblon (CRBN) is an E3 ubiquitin ligase substrate receptor that is involved in cancer cell death, although its regulation is poorly understood. Here, the authors show that Wnt ligand increases CRBN-dependent protein degradation and demonstrate CRBN
Externí odkaz:
https://doaj.org/article/b0213d02bb5e42d487d2f5912805e034
Autor:
Li Fang Ng, Prameet Kaur, Nawat Bunnag, Jahnavi Suresh, Isabelle Chiao Han Sung, Qian Hui Tan, Jan Gruber, Nicholas S. Tolwinski
Publikováno v:
Cells, Vol 8, Iss 8, p 826 (2019)
Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide ran
Externí odkaz:
https://doaj.org/article/074c049b19b44f2cbb64b04a02cf007a
Autor:
Mary Jo Cantoria, Elaheh Alizadeh, Janani Ravi, Reeba P. Varghese, Nawat Bunnag, Kelvin W. Pond, Arminja N. Kettenbach, Yashi Ahmed, Andrew L. Paek, John J. Tyson, Konstantin Doubrovinski, Ethan Lee, Curtis A. Thorne
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Wnt ligands are considered classical morphogens, for which the strength of the cellular response is proportional to the concentration of the ligand. Herein, we show an emergent property of bistability arising from feedback among the Wnt destruction c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dafa26aaf20300f9420d190447725b52
https://doi.org/10.1073/pnas.2208787120
https://doi.org/10.1073/pnas.2208787120
Autor:
Mary Jo Cantoria, Elaheh Alizadeh, Janani Ravi, Nawat Bunnag, Arminja N. Kettenbach, Yashi Ahmed, Andrew L Paek, John J. Tyson, Konstantin Doubrovinski, Ethan Lee, Curtis A. Thorne
Wnt ligands are considered classical morphogens, for which the strength of the cellular response is proportional to the concentration of the ligand. Herein, we show an emergent property of bistability arising from feedback among the Wnt destruction c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eef777e65cbb4ee7faadaaa97825dc11
https://doi.org/10.1101/2022.01.28.478206
https://doi.org/10.1101/2022.01.28.478206
Autor:
Anupriya Ramamoorthy, Prameet Kaur, Isabelle Chiao Han Sung, Jay B Lusk, Nicholas S. Tolwinski, Nawat Bunnag, Qian Hui Tan
Publikováno v:
Journal of molecular biology. 432(10)
Homeostasis in adult organs involves replacement of cells from a stem cell pool maintained in specialized niches regulated by extracellular signals. This cell-to-cell communication employs signal transduction pathways allowing cells to respond with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a93f2b1f01dffca6fe1946827da7311
https://pubmed.ncbi.nlm.nih.gov/32201167
https://pubmed.ncbi.nlm.nih.gov/32201167
Autor:
Nicholas S. Tolwinski, Jahnavi Suresh, Isabelle Chiao Han Sung, Nawat Bunnag, Qian Hui Tan, Prameet Kaur, Li Fang Ng, Jan Gruber
Publikováno v:
Cells
Cells, Vol 8, Iss 8, p 826 (2019)
Cells, Vol 8, Iss 8, p 826 (2019)
Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b596c5784d385c5ba7b9f29b5d05f2e2
https://doi.org/10.3390/cells8080826
https://doi.org/10.3390/cells8080826