Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nawal Ben Haij"'
Autor:
Nawal Ben Haij, Rémi Planès, Kaoutar Leghmari, Manutea Serrero, Pierre Delobel, Jacques Izopet, Lbachir BenMohamed, Elmostafa Bahraoui
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129425 (2015)
We recently reported that the human immunodeficiency virus type-1 (HIV-1) Tat protein induced the expression of programmed death ligand-1 (PD-L1) on dendritic cells (DCs) through a TLR4 pathway. However, the underlying mechanisms by which HIV-1 Tat p
Externí odkaz:
https://doaj.org/article/b6e118e0bf1544b7b51624b8792778e3
Autor:
Lbachir BenMohamed, Manutea Serrero, Kaoutar Leghmari, Nawal Ben Haij, Rémi Planès, Elmostafa Bahraoui
In this study, we show that the HIV-1 Tat protein interacts with rapid kinetics to engage the Toll-like receptor 4 (TLR4) pathway, leading to the production of proinflammatory and anti-inflammatory cytokines. The pretreatment of human monocytes with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b44e89ab2c49f8d65f34b60d20c8e3e
https://europepmc.org/articles/PMC4907244/
https://europepmc.org/articles/PMC4907244/
Publikováno v:
International journal of pharmaceutics. 423(1)
The objective of this study was to test the immunogenicity of SIV Nef protein formulated in cationic nanoglycolipidic particles of 100 nm of diameter. In parallel, the adjuvant effect of these nanoglycolipidic particles was compared in similar experi
Publikováno v:
Retrovirology
Retrovirology, 2013, 10 (1), pp.123. ⟨10.1186/1742-4690-10-123⟩
Retrovirology, BioMed Central, 2013, 10 (1), pp.123. 〈10.1186/1742-4690-10-123〉
Retrovirology, BioMed Central, 2013, 10 (1), pp.123. ⟨10.1186/1742-4690-10-123⟩
Retrovirology, 2013, 10 (1), pp.123. ⟨10.1186/1742-4690-10-123⟩
Retrovirology, BioMed Central, 2013, 10 (1), pp.123. 〈10.1186/1742-4690-10-123〉
Retrovirology, BioMed Central, 2013, 10 (1), pp.123. ⟨10.1186/1742-4690-10-123⟩
Background HIV-1 infection results in hyper-immune activation and immunological disorders as early as the asymptomatic stage. Here, we hypothesized that during early HIV-1 infection, HIV-1 Tat protein acts on monocytes/macrophages to induce anti-infl