Prediction of the intestinal resistome by a three-dimensional structure-based method

Autor: Willem van Schaik, Kevin Weiszer, Nicolas Maziers, Hervé M. Blottière, Luis Máiz, Nicolas Pons, Fernando Baquero, S. Dusko Ehrlich, Bruno Fantin, José L. Martínez, Amine Ghozlane, Julien Tap, Malbert R. C. Rogers, Pierre Leonard, Rob J. L. Willems, Anne-Sophie Alvarez, Florence Haimet, Etienne Ruppé, Sara Hernando-Amado, Victoire de Lastours, Alexandre G. de Brevern, Tiphaine Goulenok, Ingrid Wieder, Xinglin Zhang, Antoine Andremont, Trinidad Cuesta, Véronique Léjard, Jean-Michel Batto, Aline Letur, Nawal Amor, Joël Doré, Val F. Lanza, Teresa M. Coque, Florence Levenez, Irene Clares, Sean Kennedy

Publikováno v: Nature Microbiology
Nature Microbiology, 2019, 4 (1), pp.112-123. ⟨10.1038/s41564-018-0292-6⟩
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Digital.CSIC: Repositorio Institucional del CSIC
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Nature Microbiology, Nature Publishing Group, 2019, 4 (1), pp.112-123. ⟨10.1038/s41564-018-0292-6⟩

The intestinal microbiota is considered to be a major reservoir of antibiotic resistance determinants (ARDs) that could potentially be transferred to bacterial pathogens via mobile genetic elements. Yet, this assumption is poorly supported by empiric

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https://hal-pasteur.archives-ouvertes.fr/pasteur-02552015