Enhanced fetal hematopoiesis in response to symptomatic SARS-CoV-2 infection during pregnancy

Autor: Mansour Alkobtawi, Qui Trung Ngô, Nicolas Chapuis, Romain H. Fontaine, Mira El Khoury, Matthieu Tihy, Nawa Hachem, Aude Jary, Vincent Calvez, Michaela Fontenay, Vassilis Tsatsaris, Sélim Aractingi, Bénédicte Oulès

Publikováno v: Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)

Abstract Background Pregnant women and their fetuses are particularly susceptible to respiratory pathogens. How they respond to SARS-CoV-2 infection is still under investigation. Methods We studied the transcriptome and phenotype of umbilical cord bl

Externí odkaz: https://doaj.org/article/127cbe8f27fa4f4e9dfcabddb82bc8ae

A circulating subset of BRAFV600E-positive cells in infants with high-risk Langerhans cell histiocytosis treated with BRAF inhibitors

Autor: Jean-François Emile, J. Donadieu, Zofia Hélias-Rodzewicz, Geneviève Plat, Nawa Hachem, Sébastien Héritier, Hélène Lapillonne, Rita Poch, Solenne Le Louet, Mohamed-Aziz Barkaoui, François Delhommeau

Publikováno v: British Journal of Haematology
British Journal of Haematology, Wiley, 2021, 194 (4), pp.745-749. ⟨10.1111/bjh.17721⟩
British Journal of Haematology, 2021, 194 (4), pp.745-749. ⟨10.1111/bjh.17721⟩

International audience; BRAF inhibitors are an effective treatment for BRAFV600E-mutated, risk-organ-positive Langerhans cell histiocytosis (RO+ LCH). However, cell-free BRAFV600E DNA often persists during therapy and recurrence frequently occurs aft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20a518fb21e1d9532ec7e4e413e4a85
https://hal.archives-ouvertes.fr/hal-03401846