Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Navnath Popat Karche"'
Autor:
Sagar J. Desai, Sameer S. Walunj, Anand M. Bokare, Sharad Sharma, Dhananjay Bakhle, Sachchidanand Sachchidanand, Mahip K. Verma, Rajesh Gupta, Vijaya Mahimane, Jayasagar Gundu, Baban Rupaji Thube, Prashant B. Nigade, Firoj Aftab Raje, Chirag Shah, Sanjay Pralhad Kurhade, M. K. Singh, Lairikyengbam Bikramjit Singh, Girish Dhanraj Hatnapure, Shridhar Keshav Adurkar, Rajender Kumar Kamboj, Vinod Patil, Neelima Sinha, Ajay Ramchandra Tilekar, Sudhakar Maruti Balgude, Sarita Koul, Manavi Chatterjee, Anil Kashiram Hajare, Ruchi Dixit, Yogesh Bhosale, Ganesh Rajaram Jadhav, Manoj P. Dandekar, Navnath Popat Karche, Dnyaneshwar Changdeo Bhanage, Ashish P. Bharne, Rajan Goel, Javed S Shaikh, Gourhari Jana, Dipak Modi, Maneesh Mehta, Venkata P. Palle
Publikováno v:
Journal of Medicinal Chemistry. 63:944-960
The discovery of a series of thiophenephenylsulfonamides as positive allosteric modulators (PAM) of α7 nicotinic acetylcholine receptor (α7 nAChR) is described. Optimization of this series led to identification of compound 28, a novel PAM of α7 ni
Autor:
Anand M. Bokare, Venkata P. Palle, Maneesh Mehta, Sameer S. Walunj, Sarita Koul, Mahip K. Verma, Dipak Modi, Navnath Popat Karche, Rajan Goel, Vinod Patil, Nilendra Singh, Santoshkumar Tota, Neelima Sinha, Jayasagar Gundu, Sagar Desai, Prashant B. Nigade, Rajender Kumar Kamboj, Manoj P. Dandekar
Publikováno v:
European journal of pharmacology. 891
α7 nicotinic acetylcholine receptor (α7 nAChR) is an extensively validated target for several neurological and psychiatric conditions namely, dementia and schizophrenia, owing to its vital roles in cognition and sensorimotor gating. Positive allost