Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Navjit Hundal-Jabal"'
Autor:
Iulia Dude, Zhengxing Zhang, Julie Rousseau, Navjit Hundal-Jabal, Nadine Colpo, Helen Merkens, Kuo-Shyan Lin, François Bénard
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 2, Iss 1, Pp 1-16 (2017)
Abstract Background The somatostatin receptor subtype 2 (sstr2) is expressed on a majority of luminal breast cancers, however SPECT and scintigraphy imaging with agonistic sstr2 probes has been sub-optimal. High affinity antagonists can access more b
Externí odkaz:
https://doaj.org/article/f25e1f45ad284796aa44ebc8feb5be0a
Autor:
François Bénard, Samuel Aparicio, Silvia Jenni, Joseph Lau, Maral Pourghiasian, Navjit Hundal-Jabal, Felix Mesak, Gulisa Turashvili, Guillaume Amouroux, Jinhe Pan, Kuo-Shyan Lin
Supplementary Methods, Table 1 and Figure 1. Supplementary Methods: Peptide synthesis Table 1: detailed biodistribution data. Supplementary Figure 1: Structure of the radiolabeled peptides evaluated in this study: 68Ga-P03083 (top), 68Ga-SH01078 (mid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224d97f91ad39a8a8da28d2ada2d45af
https://doi.org/10.1158/0008-5472.22408161
https://doi.org/10.1158/0008-5472.22408161
Autor:
François Bénard, Samuel Aparicio, Silvia Jenni, Joseph Lau, Maral Pourghiasian, Navjit Hundal-Jabal, Felix Mesak, Gulisa Turashvili, Guillaume Amouroux, Jinhe Pan, Kuo-Shyan Lin
The bradykinin receptor B1R is overexpressed in many human cancers where it might be used as a general target for cancer imaging. In this study, we evaluated the feasibility of using radiolabeled kallidin derivatives to visualize B1R expression in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c62f62a2a290fdaee7b2c7e27e76f4a1
https://doi.org/10.1158/0008-5472.c.6507474.v1
https://doi.org/10.1158/0008-5472.c.6507474.v1
Autor:
Milena Čolović, Zhengxing Zhang, Xiaozhu Wang, Julie Rousseau, Navjit Hundal-Jabal, Francois Benard, Chengcheng Zhang, Etienne Rousseau, Kuo-Shyan Lin, Joseph Lau
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:899-905
Two novel bifunctional tetrahydroxamate chelators 3 and 4 were synthesized and evaluated for labeling antibodies with 89Zr for positron emission tomography imaging. Compared to previously reported tetrahydroxamate chelators 1 and 2 with an iminodiace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee2581606d8ec7e4e68c3845cd948d6f
https://doi.org/10.1016/j.bmcl.2018.01.067
https://doi.org/10.1016/j.bmcl.2018.01.067
Autor:
Kuo-Shyan Lin, Navjit Hundal-Jabal, Joseph Lau, Etienne Rousseau, Nadine Colpo, Helen Merkens, Hsiou-Ting Kuo, Zhengxing Zhang, Francois Benard
Publikováno v:
Journal of Nuclear Medicine
We evaluated the ability of monosodium glutamate (MSG) to reduce salivary and kidney uptake of a prostate-specific membrane antigen (PSMA) radioligand without affecting tumor uptake. Methods: LNCaP tumor–bearing mice were intraperitoneally injected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c840aec7f6f2e75c650b4d73aa71ec70
http://europepmc.org/articles/PMC6278899
http://europepmc.org/articles/PMC6278899
Autor:
Jinhe Pan, Navjit Hundal-Jabal, Kuo-Shyan Lin, Iulia Dude, Chengcheng Zhang, Francois Benard, Nadine Colpo, Zhengxing Zhang
Publikováno v:
Theranostics. 7:805-813
It is estimated that melanoma accounted for 76,380 new cases and 10,130 deaths in the United States in 2016. The melanocortin 1 receptor (MC1R) is highly expressed in the vast majority of melanomas, which makes it an attractive target for molecular i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc0cd3e41af913ced357456372514e7
https://doi.org/10.7150/thno.17117
https://doi.org/10.7150/thno.17117
Autor:
David M. Perrin, Navjit Hundal-Jabal, Nadine Colpo, Jutta Zeisler, Francois Benard, Helen Merkens, Chengcheng Zhang, Zhengxing Zhang, Kuo-Shyan Lin
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Since metastatic melanoma is deadly, early diagnosis thereof is crucial for managing the disease. We recently developed α-melanocyte-stimulating hormone (αMSH) derivatives, [68Ga]Ga-CCZ01048 and [18F]CCZ01064, that target the melanocortin 1 recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c0518edc0044043827cb14da5ea504
http://europepmc.org/articles/PMC6753210
http://europepmc.org/articles/PMC6753210
Autor:
Francois Benard, Navjit Hundal-Jabal, Helen Merkens, Iulia Dude, Julie Rousseau, Kuo-Shyan Lin, Nadine Colpo, Zhengxing Zhang
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 2, Iss 1, Pp 1-16 (2017)
Ejnmmi Radiopharmacy and Chemistry
Ejnmmi Radiopharmacy and Chemistry
Background: The somatostatin receptor subtype 2 (sstr2) is expressed on a majority of luminal breast cancers, however SPECT and scintigraphy imaging with agonistic sstr2 probes has been sub-optimal. High affinity antagonists can access more binding s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba425889310a91687479d37b73d5027b
Autor:
Zhibo Liu, Chengcheng Zhang, Jinhe Pan, Francois Benard, Kuo-Shyan Lin, Navjit Hundal-Jabal, Nadine Colpo, Guillaume Amouroux, Zhengxing Zhang, Silvia Jenni
Publikováno v:
Molecular Pharmaceutics. 12:2879-2888
Bradykinin B1 receptor (B1R) that is overexpressed in cancers but minimally expressed in normal healthy tissues represents an attractive biomarker for the development of cancer imaging agents. The goal of this study was to evaluate the effect of diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ad4451bd8d47adc8df0a735dbf3477
https://doi.org/10.1021/acs.molpharmaceut.5b00070
https://doi.org/10.1021/acs.molpharmaceut.5b00070
Autor:
Zhibo Liu, Nadine Colpo, Navjit Hundal-Jabal, Guillaume Amouroux, Zhengxing Zhang, Francois Benard, Joseph Lau, Silvia Jenni, Kuo-Shyan Lin, Jinhe Pan
Publikováno v:
Journal of Nuclear Medicine. 56:622-627
Bradykinin B1 receptor (B1R) is a G-protein–coupled receptor that is overexpressed in a variety of cancers. B1R is not expressed in healthy tissues, making it an attractive cancer imaging marker. Previously, we reported selective uptake of 68Ga-P03
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9111bd8fc0d6fd053695c2132d1c0cec
https://doi.org/10.2967/jnumed.114.152132
https://doi.org/10.2967/jnumed.114.152132