Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Navit, Mooshayef"'
Autor:
Efrat Ofek, Amir Onn, Arie Admon, Oranit Zadok, Sumit Chatterji, Gal Cafri, Sofia Khazan-Kost, Dganit Melamed Kadosh, Navit Mooshayef, Dan Dominissini, Sigal Manor, Bracha Zisser, Limor Broday, Efrosiniia Talalai, Anat Shemer, Michael Peled
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/9312b5ec4ecf41fab0b0731aa5ca0a02
Autor:
Rotem Lange, Allan Bar-Sinai, Adi Salzberg, Ze'ev Paroush, Shaked Bar-Cohen, Tatyana Kushnir, David Engelberg, Navit Mooshayef, Helit Rozen
Publikováno v:
Genetics. 214:109-120
Excessive RTK signaling, often caused by activating mutations in Ras, Raf and/or MEK, occurs in most human tumors. Intriguingly, confirmed cancer-driver mutations in the downstream effector kinase, ERK, have not been reported. To test if... Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c16c338521ea040fb0d3440080c2f9
https://doi.org/10.1534/genetics.119.302794
https://doi.org/10.1534/genetics.119.302794
Autor:
Sofia Khazan-Kost, Gal Cafri, Dganit Melamed Kadosh, Navit Mooshayef, Sumit Chatterji, Dan Dominissini, Sigal Manor, Bracha Zisser, Limor Broday, Efrosiniia Talalai, Anat Shemer, Oranit Zadok, Efrat Ofek, Amir Onn, Arie Admon, Michael Peled
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e003733
BackgroundSoluble human leucocyte antigen (sHLA) molecules, released into the plasma, carry their original peptide cargo and provide insight into the protein synthesis and degradation schemes of their source cells and tissues. Other body fluids, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6a7fe996b4305cc594d685467daabf
https://doi.org/10.1136/jitc-2021-003733
https://doi.org/10.1136/jitc-2021-003733
Autor:
Tatyana, Kushnir, Shaked, Bar-Cohen, Navit, Mooshayef, Rotem, Lange, Allan, Bar-Sinai, Helit, Rozen, Adi, Salzberg, David, Engelberg, Ze'ev, Paroush
Publikováno v:
Genetics
Receptor tyrosine kinase signaling plays prominent roles in tumorigenesis, and activating oncogenic point mutations in the core pathway components Ras, Raf, or MEK are prevalent in many types of cancer. Intriguingly, however, analogous oncogenic muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49a3db117bfe42666f0959e67cc26f7a
https://pubmed.ncbi.nlm.nih.gov/31740452
https://pubmed.ncbi.nlm.nih.gov/31740452
Autor:
Arie Admon, David Engelberg, Dganit Melamed, Jonah Beenstock, Navit Mooshayef, Dafna Mordechay, Natalie G. Ahn, Benjamin P. Garfinkel
Publikováno v:
Molecular and Cellular Biology. 36:1540-1554
Many enzymes are self-regulated and can either inhibit or enhance their own catalytic activity. Enzymes that do both are extremely rare. Many protein kinases autoactivate by autophosphorylating specific sites at their activation loop and are inactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718a364ffef311744f81415bb54fc381
https://doi.org/10.1128/mcb.01105-15
https://doi.org/10.1128/mcb.01105-15
Autor:
Jonah Beenstock, Tal Goshen-Lago, Dganit Melamed, Alexei Shir, Karina Smorodinsky-Atias, Yael Karamansha, Oded Livnah, Ilona Darlyuk-Saadon, Arie Admon, David Engelberg, Natalie G. Ahn, Navit Mooshayef, Anat Goldberg-Carp
Publikováno v:
Molecular Biology of the Cell
The RTK/Ras/Raf cascade is overactive in cancers. Its targets are the MAP kinases Erks, but Erks are not mutated in cancers. An active Erk, Erk1(R84S), is an oncoprotein. Further, Erk1(R84S) and Erk2(R65S) autophosphorylate the TEY motif and Thr-207/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4877c99d5b5200ba91fb891bbf33983
https://doi.org/10.1091/mbc.e15-07-0521
https://doi.org/10.1091/mbc.e15-07-0521
Publikováno v:
Trends in biochemical sciences. 41(11)
Eukaryotic protein kinases (EPKs) control most biological processes and play central roles in many human diseases. To become catalytically active, EPKs undergo conversion from an inactive to an active conformation, an event that depends upon phosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18573485fabf872c9845903c654c9c22
https://pubmed.ncbi.nlm.nih.gov/27594179
https://pubmed.ncbi.nlm.nih.gov/27594179