Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Navinisha Chetty"'
Publikováno v:
Journal of Neurogastroenterology and Motility
BACKGROUND/AIMS: Several disorders of the gastrointestinal tract are associated with abnormal serotonin (5-HT) signaling or metabolism where the 5-HT3 and 5-HT4 receptors are clinically relevant. The aim was to examine the distribution of 5-HT3, 5-HT
Publikováno v:
British Journal of Pharmacology. 148:1012-1021
This study provides a comprehensive evaluation of 5-HT(3) receptor functional distribution in both the rat and mouse intestinal tract. 5-HT(3A-S) receptor splice variant mRNA was expressed throughout the intestine of the rat and mouse; the 5-HT(3A-L)
Publikováno v:
Pharmacology. 72:220-224
The aim of this study was to obtain more information regarding the ‘atypical’ 5-HT7 receptor of the rat jejunum. 5-HT7-induced contractions of the jejunum were elicited by 5-HT in the presence of ondansetron. Maximal responses were slightly large
Autor:
Ken'ichi Yamaguchi, Akio Yasuda, Ulrich Andreas Dietz, Hitoshi Tachikawa, Norio Ogata, Palaniyandi Suresh, Gurusamy Narasimman, Toshihiro Takahashi, Juan Wen, Haruo Yamada, Masao Kakemi, Navinisha Chetty, Naohito Tanabe, Ana Paula Sendão Oliveira, Karsten Schmidt, Gerald Zernig, Yoshifusa Aizawa, Jens Kauczok, L. Meng, Shinji Sato, Ian M. Coupar, H.Bernd Reith, Katja Sturm, Meilie Ma, Koichi Ohmori, Gudrun Wakonigg, Takeshi Kashimura, Akira Yamamoto, Kenichi Watanabe, Mir Imam Ibne Wahed, Takashi Shibata, Haihuang Liu, Helen Irving, Yuichi Abe, Yean Yeow Tan, Alois Saria, Yusuke Nagai, Fadia A. Kamal, Lusiane Maria Bendhack, Mamoru Kiniwa, Naosuke Matsuura, Ulrich E. Ziegler, Makoto Miyazaki, Makoto Kodama
Publikováno v:
Pharmacology. 72:261-264
Autor:
Marshella Gozali, Karen P Kerr, Nigel Page, Francisco M. Pinto, M. Luz Candenas, Jocelyn N Pennefather, Henrik Potteck, Sebastian Ziccone, Betty Exintaris, Navinisha Chetty, Eva N Patak
Publikováno v:
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Consejo Superior de Investigaciones Científicas (CSIC)
6 páginas, 4 figuras, 1 tabla. The preprotachykinin gene Tac4 expressed in murine uterus and placenta is thought to encode a peptide RSRTRQFYGLM-NH2, mouse hemokinin 1. We have examined the uterotonic effects of mouse hemokinin 1 and its N-terminall
Publikováno v:
Pharmacology. 81(2)
The contractile activity of the novel 5-HT(3) receptor agonist MKC-733 was determined in intestinal tissues of rats, guinea pigs and mice. The potential influence of non-5-HT(3) receptors was removed by the inclusion of methysergide and GR125487. MKC
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 375(6)
The aim of this study was to demonstrate the presence of 5-HT(3) receptors in the mouse bladder and to determine their location. Bladder strips from female mice were set up in gassed Krebs-Henseleit solution at 37 degrees C and contractions recorded
Publikováno v:
British journal of pharmacology. 148(7)
This study provides a comprehensive evaluation of 5-HT(3) receptor functional distribution in both the rat and mouse intestinal tract. 5-HT(3A-S) receptor splice variant mRNA was expressed throughout the intestine of the rat and mouse; the 5-HT(3A-L)
Autor:
Ken'ichi Yamaguchi, Palaniyandi Suresh, Yean Yeow Tan, Yusuke Nagai, Gurusamy Narasimman, Gerald Zernig, Haruo Yamada, Lusiane Maria Bendhack, Navinisha Chetty, Juan Wen, Makoto Kodama, Akio Yasuda, Mir Imam Ibne Wahed, Ian M. Coupar, Katja Sturm, Makoto Miyazaki, Shinji Sato, Takeshi Kashimura, Fadia A. Kamal, Karsten Schmidt, Haihuang Liu, Helen Irving, Alois Saria, Jens Kauczok, Norio Ogata, Masao Kakemi, Meilie Ma, Hitoshi Tachikawa, Yuichi Abe, Yoshifusa Aizawa, Naosuke Matsuura, Ulrich E. Ziegler, Naohito Tanabe, Takashi Shibata, Koichi Ohmori, Kenichi Watanabe, Akira Yamamoto, Mamoru Kiniwa, Ana Paula Sendão Oliveira, L. Meng, H.Bernd Reith, Gudrun Wakonigg, Ulrich Andreas Dietz, Toshihiro Takahashi
Publikováno v:
Pharmacology. 72:265-266
Publikováno v:
Neurogastroenterology & Motility. 21:551-e15
This study aimed to examine the distribution of 5-HT receptors in the human colon. 5-HT induces desensitization of the circular muscle and as this is facilitated by G-protein coupled receptor kinases (GRKs) and other proteins, we also examined their