Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Navindee C. Wickremasinghe"'
Autor:
James T. Willerson, Qi Liu, Jeffrey D. Hartgerink, Noel R. Agudo, Yuxiao Deng, Richard A. F. Dixon, Amanda N. Moore, Alon Azares, Amanda M. Acevedo-Jake, Navindee C. Wickremasinghe, Peter Vanderslice, Su Pan, Darren G. Woodside, Toya T. Cornwright, Siyu Shi, Vivek A. Kumar
Publikováno v:
Biomaterials. 98:113-119
For a proangiogenic therapy to be successful, it must promote the development of mature vasculature for rapid reperfusion of ischemic tissue. Whole growth factor, stem cell, and gene therapies have yet to achieve the clinical success needed to become
Publikováno v:
ACS Biomaterials Science & Engineering. 1:1300-1305
Controlling perioperative bleeding is of critical importance to minimize hemorrhaging and fatality. Patients on anticoagulant therapy such as heparin have diminished clotting potential and are at risk for hemorrhaging. Here we describe a self-assembl
Autor:
Rena N. D'Souza, Navindee C. Wickremasinghe, Jeffrey D. Hartgerink, Siyu Shi, Vivek A. Kumar, Nichole L. Taylor
Publikováno v:
Biomaterials. 52:71-78
Delivery of small molecules and drugs to tissues is a mainstay of several tissue engineering strategies. Next generation treatments focused on localized drug delivery offer a more effective means in dealing with refractory healing when compared to sy
Autor:
Jeffrey D. Hartgerink, Biplab Sarkar, Navindee C. Wickremasinghe, Benjamin K. Wang, Abhishek A. Jalan, Siyu Shi, Vivek A. Kumar, I-Che Li
Publikováno v:
Journal of the American Chemical Society. 137:4823-4830
Self-assembly of multidomain peptides (MDP) can be tailored to carry payloads that modulate the extracellular environment. Controlled release of growth factors, cytokines, and small-molecule drugs allows for unique control of in vitro and in vivo res
Autor:
Nichole L. Taylor, Marci K. Kang, Navindee C. Wickremasinghe, Siyu Shi, Jeffrey D. Hartgerink, Abhishek A. Jalan, Benjamin K. Wang, Vivek A. Kumar
Publikováno v:
ACS Nano. 9:860-868
Major limitations of current tissue regeneration approaches using artificial scaffolds are fibrous encapsulation, lack of host cellular infiltration, unwanted immune responses, surface degradation preceding biointegration, and artificial degradation
Publikováno v:
Biomacromolecules
Progress in self-assembly and supramolecular chemistry has been directed toward obtaining macromolecular assemblies with higher degrees of complexity, simulating the highly structured environment in natural systems. One approach to this type of compl
Publikováno v:
ACS biomaterials scienceengineering. 1(9)
Multidomain peptide (MDP) nanofibers create scaffolds that can present bioactive cues to promote biological responses. Orthogonal self-assembly of MDPs and growth-factor-loaded liposomes generate supramolecular composite hydrogels. These composites c