Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Navin Viswakarma"'
Autor:
Mrignayani Kotecha, Longhai Wang, Safa Hameed, Navin Viswakarma, Minglin Ma, Cherie Stabler, Corinne A. Hoesli, Boris Epel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Type 1 diabetes (T1D) is an autoimmune disease that leads to the loss of insulin-producing beta cells. Bioartificial pancreas (BAP) or beta cell replacement strategies have shown promise in curing T1D and providing long-term insulin independ
Externí odkaz:
https://doaj.org/article/05593b6d0ffc431bbddc04bd561a2dcf
Autor:
Kanchan Vishnoi, Rong Ke, Navin Viswakarma, Piush Srivastava, Sandeep Kumar, Subhasis Das, Sunil Kumar Singh, Daniel R. Principe, Ajay Rana, Basabi Rana
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-16 (2022)
Abstract The incidence and mortality of hepatocellular carcinoma (HCC) are on a rise in the Western countries including US, attributed mostly to late detection. Sorafenib has been the first-line FDA-approved drug for advanced unresectable HCC for alm
Externí odkaz:
https://doaj.org/article/3ffdf7ee46924e22ae8d4086e6cc67db
Autor:
Sunil Kumar Singh, Navin Viswakarma, Gautam Sondarva, Rakesh Sathish Nair, Periannan Sethupathi, Matthew Dorman, Subhash C Sinha, Kent Hoskins, Gregory Thatcher, Basabi Rana, Ajay Rana
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background The mitogen-activated protein kinases (MAPKs) are important for T cell survival and their effector function. Mixed lineage kinase 3 (MLK3) (MAP3K11) is an upstream regulator of MAP kinases and emerging as a potential candidate for targeted
Externí odkaz:
https://doaj.org/article/a88048066d8f4bf1819a611e152d52ec
Autor:
Sandeep Kumar, Daniel R. Principe, Sunil Kumar Singh, Navin Viswakarma, Gautam Sondarva, Basabi Rana, Ajay Rana
Publikováno v:
Pharmaceuticals, Vol 13, Iss 1, p 9 (2020)
Mitogen-activated protein kinase (MAPK) signaling networks serve to regulate a wide range of physiologic and cancer-associated cell processes. For instance, a variety of oncogenic mutations often lead to hyperactivation of MAPK signaling, thereby enh
Externí odkaz:
https://doaj.org/article/1f1be3728a414f328020165017385340
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3704 (2018)
Phosphodiesterase 1C (PDE1C) is expressed in mammalian heart and regulates cardiac functions by controlling levels of second messenger cyclic AMP and cyclic GMP (cAMP and cGMP, respectively). However, molecular mechanisms of cardiac Pde1c regulation
Externí odkaz:
https://doaj.org/article/d233679b15504eacbd1fe7bb13c78082
Autor:
Yuzhi Jia, Hsiang-Chun Chang, Matthew J Schipma, Jing Liu, Varsha Shete, Ning Liu, Tatsuya Sato, Edward B Thorp, Philip M Barger, Yi-Jun Zhu, Navin Viswakarma, Yashpal S Kanwar, Hossein Ardehali, Bayar Thimmapaya, Janardan K Reddy
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160755 (2016)
Mediator, an evolutionarily conserved multi-protein complex consisting of about 30 subunits, is a key component of the polymerase II mediated gene transcription. Germline deletion of the Mediator subunit 1 (Med1) of the Mediator in mice results in mi
Externí odkaz:
https://doaj.org/article/34b28cacb9184de58569f1048c903c44
Autor:
Yuzhi Jia, Hsiang-Chun Chang, Matthew J Schipma, Jing Liu, Varsha Shete, Ning Liu, Tatsuya Sato, Edward B Thorp, Philip M Barger, Yi-Jun Zhu, Navin Viswakarma, Yashpal S Kanwar, Hossein Ardehali, Bayar Thimmapaya, Janardan K Reddy
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0164316 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0160755.].
Externí odkaz:
https://doaj.org/article/fe90b74ca63c4f07a7b0790464e0bf03
Autor:
Yuzhi Jia, Ning Liu, Navin Viswakarma, Ruya Sun, Mathew J. Schipma, Meng Shang, Edward B. Thorp, Yashpal S. Kanwar, Bayar Thimmapaya, Janardan K. Reddy
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 5, p 1485 (2018)
PIMT/NCOA6IP, a transcriptional coactivator PRIP/NCOA6 binding protein, enhances nuclear receptor transcriptional activity. Germline disruption of PIMT results in early embryonic lethality due to impairment of development around blastocyst and uterin
Externí odkaz:
https://doaj.org/article/70fc5576684749ba92da2663aa6eb196
Autor:
Angela M. Hall, Elizabeth M. Brunt, Zhouji Chen, Navin Viswakarma, Janardan K. Reddy, Nathan E. Wolins, Brian N. Finck
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 3, Pp 554-563 (2010)
Lipid droplet proteins (LDPs) coat the surface of triglyceride-rich lipid droplets and regulate their formation and lipolysis. We profiled hepatic LDP expression in fatty liver dystrophic (fld) mice, a unique model of neonatal hepatic steatosis that
Externí odkaz:
https://doaj.org/article/e4b45afc3eb54f51860e0608c52f0806
Autor:
Bandish Kapadia, Navin Viswakarma, Kishore V L Parsa, Vasundhara Kain, Soma Behera, Sashidhara Kaimal Suraj, Phanithi Prakash Babu, Anand Kar, Sunanda Panda, Yi-jun Zhu, Yuzhi Jia, Bayar Thimmapaya, Janardan K Reddy, Parimal Misra
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83787 (2013)
PRIP-Interacting protein with methyl transferase domain (PIMT) serves as a molecular bridge between CREB-binding protein (CBP)/ E1A binding protein p300 (Ep300) -anchored histone acetyl transferase and the Mediator complex sub-unit1 (Med1) and modula
Externí odkaz:
https://doaj.org/article/ac7fd69b17ac4234806af189b2eaa0c3