Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Navin Viswakarma"'
Autor:
Mrignayani Kotecha, Longhai Wang, Safa Hameed, Navin Viswakarma, Minglin Ma, Cherie Stabler, Corinne A. Hoesli, Boris Epel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Type 1 diabetes (T1D) is an autoimmune disease that leads to the loss of insulin-producing beta cells. Bioartificial pancreas (BAP) or beta cell replacement strategies have shown promise in curing T1D and providing long-term insulin independ
Externí odkaz:
https://doaj.org/article/05593b6d0ffc431bbddc04bd561a2dcf
Autor:
Kanchan Vishnoi, Rong Ke, Navin Viswakarma, Piush Srivastava, Sandeep Kumar, Subhasis Das, Sunil Kumar Singh, Daniel R. Principe, Ajay Rana, Basabi Rana
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-16 (2022)
Abstract The incidence and mortality of hepatocellular carcinoma (HCC) are on a rise in the Western countries including US, attributed mostly to late detection. Sorafenib has been the first-line FDA-approved drug for advanced unresectable HCC for alm
Externí odkaz:
https://doaj.org/article/3ffdf7ee46924e22ae8d4086e6cc67db
Autor:
Sunil Kumar Singh, Navin Viswakarma, Gautam Sondarva, Rakesh Sathish Nair, Periannan Sethupathi, Matthew Dorman, Subhash C Sinha, Kent Hoskins, Gregory Thatcher, Basabi Rana, Ajay Rana
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background The mitogen-activated protein kinases (MAPKs) are important for T cell survival and their effector function. Mixed lineage kinase 3 (MLK3) (MAP3K11) is an upstream regulator of MAP kinases and emerging as a potential candidate for targeted
Externí odkaz:
https://doaj.org/article/a88048066d8f4bf1819a611e152d52ec
Autor:
Ajay Rana, Paul J. Grippo, Hidayatullah G. Munshi, Ronald McKinney, Carolina Torres, Jonathan Rubin, Navin Viswakarma, Sandeep Kumar, Matthew J. Dorman, Alex Park, Daniel R. Principe
Figure S1 shows that T-cell deficiency of TGFBR1 promotes an immune response against established pancreatic neoplasms. Interestingly, this was not recapitulated via systemic reduction of TGFBR1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06554333f77a4e2010b1adc8862823bb
https://doi.org/10.1158/1535-7163.22505817.v1
https://doi.org/10.1158/1535-7163.22505817.v1
Autor:
Ajay Rana, Paul J. Grippo, Hidayatullah G. Munshi, Ronald McKinney, Carolina Torres, Jonathan Rubin, Navin Viswakarma, Sandeep Kumar, Matthew J. Dorman, Alex Park, Daniel R. Principe
Pancreatic ductal adenocarcinoma (PDAC) remains remarkably lethal with a 5-year survival rate of 8%. This is mainly attributed to the late stage of presentation, as well as widespread resistance to conventional therapy. In addition, PDAC tumors are l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d677048e550cb2909525bd646316a731
https://doi.org/10.1158/1535-7163.c.6538185.v1
https://doi.org/10.1158/1535-7163.c.6538185.v1
Autor:
Ajay Rana, Jose G. Trevino, Hidayatullah G. Munshi, Patrick W. Underwood, Dinesh Thummuri, Rosa F. Hwang, Melissa L. Fishel, Paul J. Grippo, Suneel D. Kamath, Matthew J. Dorman, Navin Viswakarma, Alex Park, Sandeep Kumar, Matthew Narbutis, Daniel R. Principe
Supplementary Methods, Tables, and Figure Legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9b327db48a40200193a4f49b308b02
https://doi.org/10.1158/0008-5472.22423226
https://doi.org/10.1158/0008-5472.22423226
Autor:
Ajay Rana, Jose G. Trevino, Hidayatullah G. Munshi, Patrick W. Underwood, Dinesh Thummuri, Rosa F. Hwang, Melissa L. Fishel, Paul J. Grippo, Suneel D. Kamath, Matthew J. Dorman, Navin Viswakarma, Alex Park, Sandeep Kumar, Matthew Narbutis, Daniel R. Principe
Cytotoxic chemotherapy alters the immune surface profile of Capan1 and Bxpc3 tumor cells in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66ab574aff22415e5b9ec5f2f3aa1d8
https://doi.org/10.1158/0008-5472.22423244
https://doi.org/10.1158/0008-5472.22423244
Autor:
Sandeep, Kumar, Subhasis, Das, Jingjing, Sun, Yixian, Huang, Sunil Kumar, Singh, Piush, Srivastava, Gautam, Sondarva, Rakesh Sathish, Nair, Navin, Viswakarma, Balaji B, Ganesh, Lei, Duan, Carl G, Maki, Kent, Hoskins, Oana, Danciu, Basabi, Rana, Song, Li, Ajay, Rana
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(38)
Trastuzumab is the first-line therapy for human epidermal growth factor receptor 2-positive (HER2
Autor:
Sandeep Kumar, Daniel R. Principe, Sunil Kumar Singh, Navin Viswakarma, Gautam Sondarva, Basabi Rana, Ajay Rana
Publikováno v:
Pharmaceuticals, Vol 13, Iss 1, p 9 (2020)
Mitogen-activated protein kinase (MAPK) signaling networks serve to regulate a wide range of physiologic and cancer-associated cell processes. For instance, a variety of oncogenic mutations often lead to hyperactivation of MAPK signaling, thereby enh
Externí odkaz:
https://doaj.org/article/1f1be3728a414f328020165017385340
Autor:
Subhasis Das, Daniel R. Principe, Ajay Rana, Sandeep Kumar, Navin Viswakarma, Piush Srivastava, Paul J. Grippo, Gautam Sondarva, Gregory R. J. Thatcher, Rakesh Sathish Nair, Sunil Kumar Singh, Subhash C. Sinha, Basabi Rana
Publikováno v:
Oncogene
MAP4K4 is a Ste20 member and reported to play important roles in various pathologies, including in cancer. However, the mechanism by which MAP4K4 promotes pancreatic cancer is not fully understood. It is suggested that MAP4K4 might function as a canc