Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Navid Nahiyaan"'
Autor:
Simon R. Green, Susan H. Davis, Sebastian Damerow, Curtis A. Engelhart, Michael Mathieson, Beatriz Baragaña, David A. Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K. Tamaki, Kirsteen I. Buchanan, John Post, Karen Dowers, Sharon M. Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H. Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C. Kim, James M. Bean, Navid Nahiyaan, Kyu Y. Rhee, Qinglan Wang, Vee Y. Tan, Helena I. M. Boshoff, Paul J. Converse, Si-Yang Li, Yong S. Chang, Nader Fotouhi, Anna M. Upton, Eric L. Nuermberger, Dirk Schnappinger, Kevin D. Read, Lourdes Encinas, Robert H. Bates, Paul G. Wyatt, Laura A. T. Cleghorn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Tuberculosis is a major cause of mortality, and the rise of drug-resistant strains of Mycobacterium tuberculosis requires the urgent development of safe and effective treatments. In this work, the authors develop a compound against lysyl-tRNA synthet
Externí odkaz:
https://doaj.org/article/3aefb9dc25794e5b8cda7dfd998654ed
Autor:
Roger J. Liang, Samuel Taylor, Navid Nahiyaan, Junho Song, Charles J. Murphy, Ezequiel Dantas, Shuyuan Cheng, Ting-Wei Hsu, Shakti Ramsamooj, Rahul Grover, Seo-Kyoung Hwang, Bryan Ngo, Lewis C. Cantley, Kyu Y. Rhee, Marcus D. Goncalves
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Background Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferate. Tumor cells that acquire the ability to metabolize fructose have a fitness advantage ove
Externí odkaz:
https://doaj.org/article/9ff1651a39bd47cba145113c9105b107
Autor:
Vitor Mendes, Simon R. Green, Joanna C. Evans, Jeannine Hess, Michal Blaszczyk, Christina Spry, Owain Bryant, James Cory-Wright, Daniel S-H. Chan, Pedro H. M. Torres, Zhe Wang, Navid Nahiyaan, Sandra O’Neill, Sebastian Damerow, John Post, Tracy Bayliss, Sasha L. Lynch, Anthony G. Coyne, Peter C. Ray, Chris Abell, Kyu Y. Rhee, Helena I. M. Boshoff, Clifton E. Barry, Valerie Mizrahi, Paul G. Wyatt, Tom L. Blundell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The bifunctional enzyme CoaBC catalyses the second and third step in the Coenzyme A (CoA) biosynthesis pathway and is of interest as a M. tuberculosis drug target. Here, the authors present the full-length crystal structure of Mycobacterium smegmatis
Externí odkaz:
https://doaj.org/article/dfbd7ac1fa2f42d49910fcdc7940c42e
Autor:
Chantal T Harris, Xinran Tong, Riward Campelo Morillo, Leen N Vanheer, Ines M Marreiros, Navid Nahiyaan, Vanessa A Zuzarte-Luis, Kirk W Deitsch, Maria M Mota, Kyu Y Rhee, Bjorn F. C. Kafsack
For Plasmodium falciparum, the most widespread and virulent human malaria parasite, persistence depends on continuous asexual replication in red blood cells, while transmission requires their differentiation into non-replicating gametocytes that can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b41d7d885a7e78877ee02f7510a7ded3
https://doi.org/10.1101/2022.01.18.476397
https://doi.org/10.1101/2022.01.18.476397
Autor:
Clifton E. Barry, Paul G. Wyatt, Sasha L. Lynch, Pedro Henrique Monteiro Torres, Daniel Shiu-Hin Chan, Simon Green, Helena I. Boshoff, Joanna C. Evans, Vitor Mendes, Kyu Y. Rhee, James Cory-Wright, Michal Blaszczyk, Peter C. Ray, Valerie Mizrahi, Sebastian Damerow, Navid Nahiyaan, Anthony G. Coyne, John Post, Tom L. Blundell, Tracy Bayliss, Sandra O’Neill, Chris Abell, Jeannine Hess, Christina Spry, Zhe Wang, Owain J. Bryant
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Coenzyme A (CoA) is a fundamental co-factor for all life, involved in numerous metabolic pathways and cellular processes, and its biosynthetic pathway has raised substantial interest as a drug target against multiple pathogens including Mycobacterium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93480516255c2e8d7aeba39be349059
http://europepmc.org/articles/PMC7794376
http://europepmc.org/articles/PMC7794376
Autor:
Shakti Ramsamooj, Navid Nahiyaan, Lewis C. Cantley, Kyu Y. Rhee, Lukas E. Dow, Nancy Francoeur, Marcus D. Goncalves, Emma M Schatoff, Manish A. Shah, Andrew J. Dannenberg, Roger Liang, Rita Pozovskiy, Seo-Kyoung Hwang, Jared L. Johnson, Robert Sebra, Alyna Katti, Samuel R Taylor, Neil Vasan
Publikováno v:
Nature
Fructose consumption is linked to the rising incidence of obesity and cancer, which are two of the leading causes of morbidity and mortality globally1,2. Dietary fructose metabolism begins at the epithelium of the small intestine, where fructose is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2480767876d832909deb3d86e130137d
https://pubmed.ncbi.nlm.nih.gov/35697138
https://pubmed.ncbi.nlm.nih.gov/35697138