Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Navid, Bavi"'
Publikováno v:
eLife, Vol 12 (2023)
Prestin responds to transmembrane voltage fluctuations by changing its cross-sectional area, a process underlying the electromotility of outer hair cells and cochlear amplification. Prestin belongs to the SLC26 family of anion transporters yet is the
Externí odkaz:
https://doaj.org/article/171cf7e90fbe4af1886a08282c50d10e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Mechanosensitive (MS) ion channels are primary transducers of mechanical force into electrical and/or chemical intracellular signals. Many diverse MS channel families have been shown to respond to membrane forces. As a result of this intimat
Externí odkaz:
https://doaj.org/article/b594b8b303cf425385198e18898108cc
Publikováno v:
eLife, Vol 12 (2023)
The force-from-lipids hypothesis of cellular mechanosensation posits that membrane channels open and close in response to changes in the physical state of the lipid bilayer, induced for example by lateral tension. Here, we investigate the molecular b
Externí odkaz:
https://doaj.org/article/301f810db5204175a4fe5cdde5f99558
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 1-12 (2019)
Recent rapid progress in the field of mechanobiology has been driven by novel emerging tools and methodologies and growing interest from different scientific disciplines. Specific progress has been made toward understanding how cell mechanics is link
Externí odkaz:
https://doaj.org/article/d94d5009d4fc40bc9c51b7eddc56cf70
Publikováno v:
eLife, Vol 8 (2019)
Prokaryotic mechanosensitive (MS) channels open by sensing the physical state of the membrane. As such, lipid-protein interactions represent the defining molecular process underlying mechanotransduction. Here, we describe cryo-electron microscopy (cr
Externí odkaz:
https://doaj.org/article/9a4e7fb91ebf45fdaac1e110c653e491
Autor:
Joachim Berger, Silke Berger, Mei Li, Arie S. Jacoby, Anders Arner, Navid Bavi, Alastair G. Stewart, Peter D. Currie
Publikováno v:
Cell Reports, Vol 22, Iss 2, Pp 313-322 (2018)
Summary: The TCP-1 ring complex (TRiC) is a multi-subunit group II chaperonin that assists nascent or misfolded proteins to attain their native conformation in an ATP-dependent manner. Functional studies in yeast have suggested that TRiC is an essent
Externí odkaz:
https://doaj.org/article/69e15fcc4b854123a6ac167fc71e5afc
Autor:
Navid Bavi, D. Marien Cortes, Charles D. Cox, Paul R. Rohde, Weihong Liu, Joachim W. Deitmer, Omid Bavi, Pavel Strop, Adam P. Hill, Douglas Rees, Ben Corry, Eduardo Perozo, Boris Martinac
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The activation of bacterial mechanosensitive channels is still not fully understood. Here, Bavi et al. show that the N-terminal helix of MscL dynamically couples membrane tension to channel gating, suggesting a conserved mechanism underlying the mech
Externí odkaz:
https://doaj.org/article/2a07ef9b726d4ac8a5718aab20eb0e33
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183822 (2017)
There are great opportunities in the manipulation of bacterial mechanosensitive (MS) ion channels for specific and targeted drug delivery purposes. Recent research has shown that these ion channels have the potential to be converted into nanovalves t
Externí odkaz:
https://doaj.org/article/465b40e6bebd43fda105521b755d179b
Autor:
Rong Shen, Wieslawa Milewski, Michael David Clark, Gustavo F. Contreras, Navid Bavi, Bharat Reddy, Eduardo Perozo
The voltage-dependent motor protein Prestin (SLC26A5) is responsible for the electromotive behavior of outer hair cells (OHCs) and underlies the cochlear amplifier 1. Knock out or impairment of Prestin causes severe hearing loss 2-5. Despite Prestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16f03c39a4c6a76c98c534cd026fa178
https://doi.org/10.21203/rs.3.rs-822020/v1
https://doi.org/10.21203/rs.3.rs-822020/v1
