Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Naveen Parmar"'
Autor:
Alberto Díez-Sánchez, Håvard T. Lindholm, Pia M. Vornewald, Jenny Ostrop, Rouan Yao, Andrew B. Single, Anne Marstad, Naveen Parmar, Tovah N. Shaw, Mara Martín-Alonso, Menno J. Oudhoff
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Postnatal development of the gastrointestinal tract involves the establishment of the commensal microbiota, the acquisition of immune tolerance via a balanced immune cell composition, and maturation of the intestinal epithelium. While studie
Externí odkaz:
https://doaj.org/article/754c98a67fac41cf8feb0da88289cb6f
Autor:
Pia M. Vornewald, Ruth Forman, Rouan Yao, Naveen Parmar, Håvard T. Lindholm, Lilith S. K. Lee, Mara Martín-Alonso, Kathryn J. Else, Menno J. Oudhoff
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Intestinal epithelial homeostasis is maintained by intrinsic and extrinsic signals. The extrinsic signals include those provided by mesenchymal cell populations that surround intestinal crypts and is further facilitated by the extracellular matrix (E
Externí odkaz:
https://doaj.org/article/5662fcecce6d4c588ab6033c643948ce
Autor:
Saykat Das, Jorunn Stamnaes, Esko Kemppainen, Kaisa Hervonen, Knut E. A. Lundin, Naveen Parmar, Frode L. Jahnsen, Jørgen Jahnsen, Katri Lindfors, Teea Salmi, Rasmus Iversen, Ludvig M. Sollid
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Dermatitis herpetiformis (DH) is an inflammatory skin disorder often considered as an extra intestinal manifestation of celiac disease (CeD). Hallmarks of CeD and DH are auto‐antibodies to transglutaminase 2 (TG2) and transglutaminase 3 (T
Externí odkaz:
https://doaj.org/article/c03947c46ced4f9ebf35f637435e6e72
Autor:
Naveen Parmar, Kyle Burrows, Pia M Vornewald, Håvard T Lindholm, Rosalie T Zwiggelaar, Alberto Díez-Sánchez, Mara Martín-Alonso, Madeleine Fosslie, Bruce A Vallance, John Arne Dahl, Colby Zaph, Menno J Oudhoff
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009476 (2021)
Infectious and inflammatory diseases in the intestine remain a serious threat for patients world-wide. Reprogramming of the intestinal epithelium towards a protective effector state is important to manage inflammation and immunity and can be therapeu
Externí odkaz:
https://doaj.org/article/6a34613768804c59bee0718fbb1e24ef
Autor:
Jenny Ostrop, Rosalie T. Zwiggelaar, Marianne Terndrup Pedersen, François Gerbe, Korbinian Bösl, Håvard T. Lindholm, Alberto Díez-Sánchez, Naveen Parmar, Silke Radetzki, Jens Peter von Kries, Philippe Jay, Kim B. Jensen, Cheryl Arrowsmith, Menno J. Oudhoff
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Intestinal organoids are an excellent model to study epithelial biology. Yet, the selection of analytical tools to accurately quantify heterogeneous organoid cultures remains limited. Here, we developed a semi-automated organoid screening method, whi
Externí odkaz:
https://doaj.org/article/aecc2679ef1d45a8875277b91cd0b5d7
Autor:
Rahul Shivahare, Preeti Vishwakarma, Naveen Parmar, Pawan Kumar Yadav, Wahajul Haq, Mrigank Srivastava, Suman Gupta, Susanta Kar
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94596 (2014)
Immuno-modulators in combination with antileishmanial drug miltefosine is a better therapeutic approach for treatment of Visceral Leishmaniasis (VL) as it not only reduces the dose of miltefosine but also shortens the treatment regimen. However, immu
Externí odkaz:
https://doaj.org/article/688ecedf1c5d4390a8f65de6fc86ec70
Autor:
Håvard T. Lindholm, Naveen Parmar, Claire Drurey, Marta Campillo Poveda, Pia M. Vornewald, Jenny Ostrop, Alberto Díez-Sanchez, Rick M. Maizels, Menno J. Oudhoff
Publikováno v:
Science Immunology. 7
The intestinal tract is a common site for various types of infections including viruses, bacteria, and helminths, each requiring specific modes of immune defense. The intestinal epithelium has a pivotal role in both immune initiation and effector sta
Publikováno v:
The Journal of Immunology. 204:2762-2778
Reciprocal changes in histone lysine methylation/demethylation of M(LPS + IFN-γ)/M(IL-10) genes is one of the factors that direct macrophage polarization and contribute to host defense/susceptibility toward infection. Although, histone lysine methyl
Publikováno v:
The Journal of Immunology. 204:596-610
Immune evasion strategies adopted by Leishmania donovani involve the exploitation of suppressor of cytokine signaling (SOCS) proteins that are well-known negative regulators of the JAK/STAT pathway. However, the cellular mechanism underpinning the in
Autor:
Mrigank Srivastava, Preeti Vishwakarma, Pankaj Sharma, Pawan Kumar Yadav, Naveen Parmar, Pragya Chandrakar, Susanta Kar
Publikováno v:
Vaccine. 38:355-365
CD11c+CD8α+ and CD11c+CD11b+ dendritic cells are two major subsets of murine splenic CD11c+ DCs which play a crucial role in T cell priming and shaping Th1/Th2 responses, but their role in the context of experimental visceral leishmaniasis (VL) is p