Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Naveen Kumar Khare"'
Autor:
Gorantla V. Raghuram, Bhabesh Kumar Tripathy, Kartikeya Avadhani, Snehal Shabrish, Naveen Kumar Khare, Relestina Lopes, Kavita Pal, Indraneel Mittra
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Mitochondrial damage and the resultant oxidative stress are associated with neurodegenerative diseases, ageing, and cancer. However, the triggers of mitochondrial damage remain unclear. We previously reported that cell-free chromatin particl
Externí odkaz:
https://doaj.org/article/a9cc4ee781b94e82afaa0532b25a06b0
Autor:
Snehal Shabrish, Kavita Pal, Naveen Kumar Khare, Dharana Satsangi, Aishwarya Pilankar, Vishalkumar Jadhav, Sushma Shinde, Nimisha Raphael, Gaurav Sriram, Relestina Lopes, Gorantla V. Raghuram, Harshali Tandel, Indraneel Mittra
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Immune checkpoint blockade is the exciting breakthrough in cancer, but how immune checkpoints are activated is unknown. We have earlier reported that cell-free chromatin particles (cfChPs) that circulate in blood of cancer patients, or those that are
Externí odkaz:
https://doaj.org/article/f21034dd251d4b50bba118ffa67941e6
Autor:
Aishwarya Pilankar, Hitesh Singhavi, Gorantla V. Raghuram, Sophiya Siddiqui, Naveen Kumar Khare, Vishalkumar Jadhav, Harshali Tandel, Kavita Pal, Atanu Bhattacharjee, Pankaj Chaturvedi, Indraneel Mittra
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundOur earlier studies have shown that cell-free chromatin particles (cfChPs) that are released from dying cancer cells are readily internalised by bystander cells leading to activation of two hallmarks of cancer viz. genome instability and in
Externí odkaz:
https://doaj.org/article/220990f158fe4255bb55e378be9807f8
Autor:
Anshul Agarwal, Aakanksha Khandelwal, Kavita Pal, Naveen Kumar Khare, Vishal Jadhav, Murarilal Gurjar, Sachin Punatar, Anant Gokarn, Avinash Bonda, Lingaraj Nayak, Sadhana Kannan, Vikram Gota, Navin Khattry, Indraneel Mittra
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0262212 (2022)
BackgroundTransplant related toxicity is a major therapeutic challenge. We have previously reported that the toxicity of chemotherapy is largely not directly because of the drugs themselves; rather it is mainly due to DNA damage, apoptosis and hyper-
Externí odkaz:
https://doaj.org/article/f152dab89d3b449491212da2ac9f526b
Autor:
Pradyumna Kumar Mishra, Gorantla Venkata Raghuram, Neha Bunkar, Arpit Bhargava, Naveen Kumar Khare
Publikováno v:
International Journal of Occupational Medicine and Environmental Health, Vol 28, Iss 6, Pp 921-939 (2015)
December 2014 marked the 30th year anniversary of Bhopal gas tragedy. This sudden and accidental leakage of deadly poisonous methyl isocyanate (MIC) gas instigated research efforts to understand the nature, severity of health damage and sufferings of
Externí odkaz:
https://doaj.org/article/05eaf7642c794e15a27e27822500a715
Autor:
Bhabesh Kumar Tripathy, Kartikeya Avadhani, Gorantla V Raghuram, Kavita Pal, Naveen Kumar Khare, Relestina Lopes, Indraneel Mittra
Several hundred billion to a trillion cells die in the body every day and release cell free chromatin particles (cfChPs) which enter into the circulation, or are released locally into extracellular compartments of the body. We have reported that cfCh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac209a276d1b013635167f990a602fa5
https://doi.org/10.1101/2021.12.30.474529
https://doi.org/10.1101/2021.12.30.474529
Autor:
Kavita Pal, Venkat Raghuram Gorantla, Vishalkumar Jadhav, Hitesh Singhavi, Sophiya Siddiqui, Naveen Kumar Khare, Indraneel Mittra, Pankaj Chaturvedi, Aishwarya Pilankar
Publikováno v:
Cancer Research. 81:2514-2514
Background: We have reported that combination of the nutraceuticals Resveratrol (R) and Copper(Cu) results in generation of free radicals which can degrade cell-free chromatin (cfCh) particles and have potential therapeutic effects (Mittra et al., An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbf51e9cb63ae2c25837949eb3176afe
https://doi.org/10.1158/1538-7445.am2021-2514
https://doi.org/10.1158/1538-7445.am2021-2514
Autor:
Soniya Shende, Indraneel Mittra, Venkata Raghuram Gorantla, Kavita Pal, Ratnam Prasad, Harshada Wani, Naveen Kumar Khare
Publikováno v:
Cancer Research. 81:2875-2875
Background: According to the current paradigm, metastases arise from cells of the primary tumor that have intravasated into circulation and carried to distant organs where they extravasate, grow and form new tumors. However, mechanisms underlying the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d999d29b6dd24e006da286e9a5dea6c7
https://doi.org/10.1158/1538-7445.am2021-2875
https://doi.org/10.1158/1538-7445.am2021-2875
Autor:
Jenevieve D’souza, Naveen Kumar Khare, Indraneel Mittra, Dharana Satsangi, Shahid Chaudhary, Ratnam Prasad, Kavita Pal, Harshada Wani, Shweta Johari, Soniya Shende, Tannistha Saha
Publikováno v:
Cancer Research. 81:2067-2067
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2772b3b615031bef471e6c7e1e6a29ce
https://doi.org/10.1158/1538-7445.am2021-2067
https://doi.org/10.1158/1538-7445.am2021-2067
Autor:
H. Nagare, Alfina Shaikh, Naveen K Nair, Namrata Pancholi, Pritishkumar Tidke, Indraneel Mittra, K. Agrawal, Naveen Kumar Khare, Bhagyeshri Rane, Saurabh Kirolikar, Kavita Pal
Publikováno v:
Annals of Oncology. 28:2119-2127
Background Toxicity associated with chemotherapy is a major therapeutic challenge and is caused by chemotherapy-induced DNA damage and inflammation. We have recently reported that cell-free chromatin (cfCh) fragments released from dying cells can rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3e0267d4f33c831d7d5893faebdd94
https://doi.org/10.1093/annonc/mdx318
https://doi.org/10.1093/annonc/mdx318