Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Naveen K Singhal"'
Autor:
Sarah Sternbach, Nicole West, Naveen K Singhal, Robert Clements, Soumitra Basu, Ajai Tripathi, Ranjan Dutta, Ernest J Freeman, Jennifer McDonough
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250486 (2021)
Research into the epigenome is of growing importance as a loss of epigenetic control has been implicated in the development of neurodegenerative diseases. Previous studies have implicated aberrant DNA and histone methylation in multiple sclerosis (MS
Externí odkaz:
https://doaj.org/article/5bd87210533d461f8add0704beed3259
Autor:
Daniela C Popescu, He Huang, Naveen K Singhal, Leah Shriver, Jennifer McDonough, Robert J Clements, Ernest J Freeman
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0203057 (2018)
Multiple sclerosis (MS) is a devastating neurological disease, which is characterized by multifocal demyelinating lesions in the central nervous system. The most abundant myelin lipids are galactosylceramides and their sulfated form, sulfatides, whic
Externí odkaz:
https://doaj.org/article/5ce6b699c7154ba0814cb46b62b65ab8
Autor:
Jennifer McDonough, Naveen K. Singhal, Paulina M. Getsy, Katherine Knies, Zackery T. Knauss, Devin Mueller, James N. Bates, Derek S. Damron, Stephen J. Lewis
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
We have reported that D,L-thiol esters, including D-cysteine ethyl ester (D-CYSee), are effective at overcoming opioid-induced respiratory depression (OIRD) in rats. Our on-going studies reveal that co-injections of D-CYSee with multi-day morphine in
Externí odkaz:
https://doaj.org/article/b770ebd95e5f4062957719f54007718e
Autor:
Jiho Sohn, Peter Bannerman, Fuzheng Guo, Travis Burns, Laird Miers, Christopher Croteau, Naveen K. Singhal, Jennifer A. McDonough, David Pleasure
Publikováno v:
The Journal of Neuroscience. 37:413-421
Publikováno v:
Croatica Chemica Acta
Volume 71
Issue 3
Volume 71
Issue 3
The electrochemical reduction of bisazo dye Direct Orange–31 has been studied at Pyrolytic graphite electrode (PGE) in the pH range 2.0–10.3. Two well-defined 4e–, 4H+ pH dependent reduction peaks (Ic & IIc ) have been observed in linear and cy
Autor:
Naveen K. Singhal, Sarah Sternbach, Sheila Fleming, Kholoud Alkhayer, John Shelestak, Daniela Popescu, Alyx Weaver, Robert Clements, Brandi Wasek, Teodoro Bottiglieri, Ernest J. Freeman, Jennifer McDonough
Publikováno v:
Epigenetics, Vol 15, Iss 8, Pp 871-886 (2020)
Methionine metabolism is dysregulated in multiple sclerosis (MS). The methyl donor betaine is depleted in the MS brain where it is linked to changes in levels of histone H3 trimethylated on lysine 4 (H3K4me3) and mitochondrial impairment. We investig
Externí odkaz:
https://doaj.org/article/1e99bbf5df564768825be462cd0c5a7e