Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Naveen Jayaprakash"'
Autor:
Federico Ciotti, Robert John, Natalija Katic Secerovic, Noemi Gozzi, Andrea Cimolato, Naveen Jayaprakash, Weiguo Song, Viktor Toth, Theodoros Zanos, Stavros Zanos, Stanisa Raspopovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Bioelectronic therapies modulating the vagus nerve are promising for cardiovascular, inflammatory, and mental disorders. Clinical applications are however limited by side-effects such as breathing obstruction and headache caused by non-speci
Externí odkaz:
https://doaj.org/article/f961fa4d668f430fa89aa693cfe5e62c
Autor:
Ibrahim T. Mughrabi, Michael Gerber, Naveen Jayaprakash, Santhoshi P. Palandira, Yousef Al-Abed, Timir Datta-Chaudhuri, Corey Smith, Valentin A. Pavlov, Stavros Zanos
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background The noradrenergic innervation of the spleen is implicated in the autonomic control of inflammation and has been the target of neurostimulation therapies for inflammatory diseases. However, there is no real-time marker of its succe
Externí odkaz:
https://doaj.org/article/89e0b92ee1164d0a8b1115da6bbd4daa
Autor:
Naveen Jayaprakash, Weiguo Song, Viktor Toth, Avantika Vardhan, Todd Levy, Jacquelyn Tomaio, Khaled Qanud, Ibrahim Mughrabi, Yao-Chuan Chang, Moontahinaz Rob, Anna Daytz, Adam Abbas, Zeinab Nassrallah, Bruce T. Volpe, Kevin J. Tracey, Yousef Al-Abed, Timir Datta-Chaudhuri, Larry Miller, Mary F. Barbe, Sunhee C. Lee, Theodoros P. Zanos, Stavros Zanos
Publikováno v:
Brain Stimulation, Vol 16, Iss 2, Pp 484-506 (2023)
Vagal fibers travel inside fascicles and form branches to innervate organs and regulate organ functions. Existing vagus nerve stimulation (VNS) therapies activate vagal fibers non-selectively, often resulting in reduced efficacy and side effects from
Externí odkaz:
https://doaj.org/article/98dc21c6939945af94101697d88b381f
Autor:
Yao-Chuan Chang, Umair Ahmed, Naveen Jayaprakash, Ibrahim Mughrabi, Qihang Lin, Yi-Chen Wu, Michael Gerber, Adam Abbas, Anna Daytz, Arielle H. Gabalski, Jason Ashville, Socrates Dokos, Loren Rieth, Timir Datta-Chaudhuri, Kevin J. Tracey, Tianruo Guo, Yousef Al-Abed, Stavros Zanos
Publikováno v:
Brain Stimulation, Vol 15, Iss 6, Pp 1389-1404 (2022)
Background: Vagal reflexes regulate homeostasis in visceral organs and systems through afferent and efferent neurons and nerve fibers. Small, unmyelinated, C-type afferents comprise over 80% of fibers in the vagus and form the sensory arc of autonomi
Externí odkaz:
https://doaj.org/article/42a0208fdf1541a38a60370b2b0903c8
Autor:
Naveen Jayaprakash, Viktor Toth, Weiguo Song, Moontahinaz Rob, Anna Daytz, Sunhee Lee, Theodoros Zanos, Yousef Al-Abed, Stavros Zanos
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 297- (2023)
Externí odkaz:
https://doaj.org/article/e5116f91a46f4bf2981d8a0bc763107d
Autor:
Umair Ahmed, John F. Graf, Anna Daytz, Omar Yaipen, Ibrahim Mughrabi, Naveen Jayaprakash, Victoria Cotero, Christine Morton, Clifford Scott Deutschman, Stavros Zanos, Chris Puleo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interfaces between the nervous and immune systems have been shown essential for the coordination and regulation of immune responses. Non-invasive ultrasound stimulation targeted to the spleen has recently been shown capable of activating one such int
Externí odkaz:
https://doaj.org/article/7100c06e3361460e981f88de1cfc2dce
Autor:
Ibrahim T Mughrabi, Jordan Hickman, Naveen Jayaprakash, Dane Thompson, Umair Ahmed, Eleni S Papadoyannis, Yao-Chuan Chang, Adam Abbas, Timir Datta-Chaudhuri, Eric H Chang, Theodoros P Zanos, Sunhee C Lee, Robert C Froemke, Kevin J Tracey, Cristin Welle, Yousef Al-Abed, Stavros Zanos
Publikováno v:
eLife, Vol 10 (2021)
Vagus nerve stimulation (VNS) suppresses inflammation and autoimmune diseases in preclinical and clinical studies. The underlying molecular, neurological, and anatomical mechanisms have been well characterized using acute electrophysiological stimula
Externí odkaz:
https://doaj.org/article/00fccd68672b49909ac33099dcf37e3b
Autor:
Stefanos Zafeiropoulos, Umair Ahmed, Ibrahim T Mughrabi, Naveen Jayaprakash, Chrystal Chadwick, Anna Daytz, Alexandra Bekiaridou, Nafiseh Saleknezhad, Yemil Atish-Fregoso, Kaitlin Carroll, George Giannakoulas, Yousef Al-Abed, Christopher Puleo, Mark Nicolls, Betty Diamond, Stavros Zanos
RationaleChronic inflammation is pathogenically implicated in pulmonary arterial hypertension (PAH), however, it has not been adequately targeted therapeutically.ObjectivesWe investigated whether neuromodulation of an anti-inflammatory neuroimmune pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0940cbac28ceb3ca7af5ee5ef36ef49
https://doi.org/10.1101/2023.03.28.534567
https://doi.org/10.1101/2023.03.28.534567
Autor:
Ibrahim T. Mughrabi, Michael Gerber, Naveen Jayaprakash, Santhoshi P. Palandira, Yousef Al-Abed, Timir Datta-Chaudhuri, Corey Smith, Valentin A. Pavlov, Stavros Zanos
BackgroundThe noradrenergic innervation of the spleen is implicated in the autonomic control of inflammation and has been the target of neurostimulation therapies for inflammatory diseases. However, there is no real-time marker of its successful acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf2a84daef79c8b4f3a54b20fbfbe22
https://doi.org/10.1101/2022.04.26.489592
https://doi.org/10.1101/2022.04.26.489592
Autor:
Naveen Jayaprakash, Weiguo Song, Viktor Toth, Avantika Vardhan, Todd Levy, Jacquelyn Tomaio, Khaled Qanud, Ibrahim Mughrabi, Yao-Chuan Chang, Moontahinaz Rob, Anna Daytz, Adam Abbas, Zeinab Nassrallah, Bruce T. Volpe, Kevin J. Tracey, Yousef Al-Abed, Timir Datta-Chaudhuri, Larry Miller, Mary F. Barbe, Sunhee C. Lee, Theodoros P. Zanos, Stavros Zanos
Vagal fibers travel inside fascicles and form branches to innervate organs and regulate organ functions. Vagus nerve stimulation (VNS) therapies activate fibers non-selectively, often resulting in reduced efficacy and side effects from non-targeted o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686e45819df8237dbfa65e46c8a998df
https://doi.org/10.1101/2022.03.07.483266
https://doi.org/10.1101/2022.03.07.483266