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Prevalence and characteristics of chronic kidney disease in people with type 2 diabetes mellitus in the Autonomous Community of Aragon.

Autor: Sánchez-Calavera MA; Health Service of Aragon, Spain; Instituto de Investigación Sanitaria de Aragón (IISA, Aragon Health Research Institute), Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Navarro RG; Health Service of Aragon, Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain. Electronic address: rgomezn@salud.aragon.es., Otal EA; Health Service of Aragon, Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., González IB; Health Service of Aragon, Spain; Instituto de Investigación Sanitaria de Aragón (IISA, Aragon Health Research Institute), Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Pardo DE; Health Service of Aragon, Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Celma LH; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Lamarre M; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Esteban PL; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Lozano Del Hoyo ML; Health Service of Aragon, Spain; Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Mahulea L; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Gallego IM; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain; Sociedad Española de Farmacia Clínica, Familiar y Comunitaria (Spanish Society of Clinical, Family and Community Pharmacy), Spain., Romero-Vigara JC; Health Service of Aragon, Spain; Instituto de Investigación Sanitaria de Aragón (IISA, Aragon Health Research Institute), Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Allué SS; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Hueso ST; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain., Gil FA; Health Service of Aragon, Spain; Red de Grupos de Estudio de la Diabetes en Atención Primaria de Salud (redGDPS, Network of Diabetes Study Groups in Primary Healthcare), Spain.

Publikováno v: Primary care diabetes [Prim Care Diabetes] 2024 Oct; Vol. 18 (5), pp. 555-560. Date of Electronic Publication: 2024 Jul 10.

Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors.

Autor: Westhaus A; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Cabanes-Creus M; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Dilworth KL; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Zhu E; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Salas Gómez D; Gene Therapy and Regulation of Gene Expression Department, IdiSNA, Instituto de Investigación Sanitaria de Navarra, Universidad de Navarra, CIMA, Pamplona, Spain., Navarro RG; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Amaya AK; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Scott S; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Australian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation, Sydney, Australia., Kwiatek M; Military Institute of Hygiene and Epidemiology, The Biological Threats Identification and Countermeasure Centre, Puławy, Poland., McCorkindale AL; Inventia Life Science Pty Ltd., Sydney, Australia., Hayman TE; Inventia Life Science Pty Ltd., Sydney, Australia., Frahm S; Stem Cell Technology Platform, Max Delbrück Centrum for Molecular Medicine, Berlin, Germany., Perocheau DP; Genetics and Genomic Medicine Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.; Metabolic Medicine Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.; National Institute of Health Research Great Ormond Street Hospital Biomedical Research Centre, London, United Kingdom., Tran BM; Department of Infectious Diseases, Melbourne Medical School, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Vincan E; Department of Infectious Diseases, Melbourne Medical School, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Curtin Medical School, Curtin University, Perth, Australia., Wong SL; Molecular and Integrative Cystic Fibrosis (miCF) Research Centre, University of New South Wales and Sydney Children's Hospital, Sydney, Australia.; School of Biomedical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia., Waters SA; Molecular and Integrative Cystic Fibrosis (miCF) Research Centre, University of New South Wales and Sydney Children's Hospital, Sydney, Australia.; School of Biomedical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia.; Department of Respiratory Medicine, Sydney Children's Hospital, Faculty of Medicine, University of New South Wales, Sydney, Australia., Riddiough GE; Department of Infectious Diseases, Melbourne Medical School, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Heidelberg, Australia., Perini MV; Department of Surgery, Austin Health Precinct, The University of Melbourne, Austin Health, Heidelberg, Australia., Wilson LOW; Australian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation, Sydney, Australia.; Applied BioSciences, Faculty of Science and Engineering, Macquarie University, Sydney, Australia., Baruteau J; Genetics and Genomic Medicine Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.; Metabolic Medicine Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.; National Institute of Health Research Great Ormond Street Hospital Biomedical Research Centre, London, United Kingdom., Diecke S; Stem Cell Technology Platform, Max Delbrück Centrum for Molecular Medicine, Berlin, Germany., González-Aseguinolaza G; Gene Therapy and Regulation of Gene Expression Department, IdiSNA, Instituto de Investigación Sanitaria de Navarra, Universidad de Navarra, CIMA, Pamplona, Spain., Santilli G; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Thrasher AJ; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Alexander IE; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Discipline of Child and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Lisowski L; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Vector and Genome Engineering Facility, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine, Warszawa, Poland.

Publikováno v: Human gene therapy [Hum Gene Ther] 2023 Apr; Vol. 34 (7-8), pp. 273-288.

Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution.

Autor: Cabanes-Creus M; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia., Navarro RG; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia., Liao SHY; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia., Scott S; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia., Carlessi R; Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA 6102, Australia.; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Nedlands, WA 6009, Australia., Roca-Pinilla R; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia., Knight M; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia., Baltazar G; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia., Zhu E; Gene Therapy Research Unit, Children's Medical Research Institute and The Children's Hospital at Westmead, Faculty of Medicine and Health, The University of Sydney, and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia., Jones M; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Nedlands, WA 6009, Australia., Denisenko E; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Nedlands, WA 6009, Australia., Forrest ARR; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Nedlands, WA 6009, Australia., Alexander IE; Gene Therapy Research Unit, Children's Medical Research Institute and The Children's Hospital at Westmead, Faculty of Medicine and Health, The University of Sydney, and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia.; Discipline of Child and Adolescent Health, The University of Sydney, Sydney Medical School, Faculty of Medicine and Health, Westmead, NSW 2145, Australia., Tirnitz-Parker JEE; Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA 6102, Australia.; UWA Centre for Medical Research, The University of Western Australia, Nedlands, WA 6009, Australia., Lisowski L; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine, 04-141 Warsaw, Poland.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2023 Jan 02; Vol. 28, pp. 220-237. Date of Electronic Publication: 2023 Jan 02 (Print Publication: 2023).

Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8.

Autor: Cabanes-Creus M; Translational Vectorology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia., Navarro RG; Translational Vectorology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia., Zhu E; Gene Therapy Research Unit, Children's Medical Research Institute & The Children's Hospital at Westmead, The University of Sydney, Westmead, NSW 2145, Australia., Baltazar G; Translational Vectorology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia., Liao SHY; Translational Vectorology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia., Drouyer M; Translational Vectorology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia., Amaya AK; Gene Therapy Research Unit, Children's Medical Research Institute & The Children's Hospital at Westmead, The University of Sydney, Westmead, NSW 2145, Australia., Scott S; Gene Therapy Research Unit, Children's Medical Research Institute & The Children's Hospital at Westmead, The University of Sydney, Westmead, NSW 2145, Australia.; Commonwealth Scientific and Industrial Research Organisation (CSIRO), North Ryde, NSW 2113, Australia., Nguyen LH; Translational Vectorology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia., Westhaus A; Translational Vectorology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia.; Great Ormond Institute of Child Health, University College London, WC1N 1EH London, UK., Hebben M; LogicBio Therapeutics, 65 Hayden avenue, Lexington, 02421 MA, USA., Wilson LOW; Commonwealth Scientific and Industrial Research Organisation (CSIRO), North Ryde, NSW 2113, Australia., Thrasher AJ; Great Ormond Institute of Child Health, University College London, WC1N 1EH London, UK., Alexander IE; Gene Therapy Research Unit, Children's Medical Research Institute & The Children's Hospital at Westmead, The University of Sydney, Westmead, NSW 2145, Australia.; Discipline of Child and Adolescent Health, The University of Sydney, Sydney Medical School, Faculty of Medicine and Health, Westmead, NSW 2145, Australia., Lisowski L; Translational Vectorology Research Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia.; Vector and Genome Engineering Facility, Children's Medical Research Institute, The University of Sydney, Westmead, NSW 2145, Australia.; Military Institute of Medicine, Laboratory of Molecular Oncology and Innovative Therapies, 04-141 Warsaw, Poland.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2021 Nov 25; Vol. 24, pp. 88-101. Date of Electronic Publication: 2021 Nov 25 (Print Publication: 2022).