Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Nausicaa Clemente"'
Autor:
Giulia Pinton, Mattia Perucca, Valentina Gigliotti, Elena Mantovani, Nausicaa Clemente, Justyna Malecka, Gabriela Chrostek, Giulia Dematteis, Dmitry Lim, Laura Moro, Fausto Chiazza
Publikováno v:
Nutrients, Vol 16, Iss 19, p 3260 (2024)
Background/Objectives: Methyltransferase EZH2-mediated H3K27me3 is involved in liver inflammation and fibrosis, but its role in hepatic metabolic derangements is not yet clearly defined. We investigated if a high-fat diet (HFD) induced early changes
Externí odkaz:
https://doaj.org/article/9a2269978b4645b6922701ddb9366ff8
Autor:
Laura Salvadori, Martina Paiella, Beatrice Castiglioni, Maria Laura Belladonna, Tommaso Manenti, Catia Ercolani, Luca Cornioli, Nausicaa Clemente, Andrea Scircoli, Roccaldo Sardella, Leonardo Tensi, Andrea Astolfi, Maria Letizia Barreca, Sara Chiappalupi, Giulia Gentili, Michela Bosetti, Guglielmo Sorci, Nicoletta Filigheddu, Francesca Riuzzi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116517- (2024)
Age-associated osteosarcopenia is an unresolved syndrome characterized by the concomitant loss of bone (osteopenia) and skeletal muscle (sarcopenia) tissues increasing falls, immobility, morbidity, and mortality. Unbalanced resorption of bone in the
Externí odkaz:
https://doaj.org/article/97bc4b8e0e214e6db8299f67a2fb442e
Autor:
Nausicaa Clemente, Simona Baroni, Simone Fiorilla, Francesco Tasso, Simone Reano, Chiara Borsotti, Maria Rosaria Ruggiero, Elisa Alchera, Marco Corrazzari, Gillian Walker, Antonia Follenzi, Simonetta Geninatti Crich, Rita Carini
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Pharmacological treatments for advanced hepatocellular carcinoma (HCC) have a partial efficacy. Augmented Na+ content and water retention are observed in human cancers and offer unexplored targets for anticancer therapies. Na+ levels are eva
Externí odkaz:
https://doaj.org/article/7b9e3af363b549a185401d7669fa6d39
Autor:
Mario Paolo Colombo, Joe G N Garcia, Cristina Travelli, Giorgia Colombo, Martina Aliotta, Francesca Fagiani, Natalia Fava, Rita De Sanctis, Ambra A Grolla, Nausicaa Clemente, Paola Portararo, Massimo Costanza, Fabrizio Condorelli, Sabina Sangaletti, Armando A Genazzani
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Nicotinamide phosphoribosyltransferase (NAMPT) is a key intracellular enzyme that participates in nicotinamide adenine dinucleotide (NAD) homeostasis as well as a released cytokine (eNAMPT) that is elevated in inflammatory conditions and i
Externí odkaz:
https://doaj.org/article/c682ddf856af461abc7e0fc0260b779f
Autor:
Ian Stoppa, Chiara Dianzani, Nausicaa Clemente, Annalisa Bozza, Valentina Bordano, Sara Garelli, Luigi Cangemi, Umberto Dianzani, Luigi Battaglia
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 238 (2024)
Bone is a site of distant metastases, which are a common cause of morbidity and mortality with a high socio-economic impact, for many malignant tumours. In order to engineer pharmacological therapies that are suitable for this debilitating disease, t
Externí odkaz:
https://doaj.org/article/64c0d3947aa24a85969c2d506d96458c
Autor:
Gustavo Ferreira Alves, Ian Stoppa, Eleonora Aimaretti, Chiara Monge, Raffaella Mastrocola, Elisa Porchietto, Giacomo Einaudi, Debora Collotta, Ilaria Bertocchi, Elena Boggio, Casimiro Luca Gigliotti, Nausicaa Clemente, Manuela Aragno, Daniel Fernandes, Carlo Cifani, Christoph Thiemermann, Chiara Dianzani, Umberto Dianzani, Massimo Collino
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inducible T cell co-stimulator (ICOS), an immune checkpoint protein expressed on activated T cells and its unique ligand, ICOSL, which is expressed on antigen-presenting cells and non-hematopoietic cells, have been extensively investigated in the imm
Externí odkaz:
https://doaj.org/article/1c55e496fa97413c9846216878568c2f
Autor:
Mara Gagliardi, Nausicaa Clemente, Romina Monzani, Luca Fusaro, Eleonora Ferrari, Valentina Saverio, Giovanna Grieco, Elżbieta Pańczyszyn, Flavia Carton, Claudio Santoro, Sara Del Mare-Roumani, Sivan Amidror, Nissan Yissachar, Francesca Boccafoschi, Silvia Zucchelli, Marco Corazzari
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Celiac disease (CD) is a complex immune-mediated chronic disease characterized by a consistent inflammation of the gastrointestinal tract induced by gluten intake in genetically predisposed individuals. Although initiated by the interaction
Externí odkaz:
https://doaj.org/article/6d68940d7e6942889c1d1acb6068e810
Autor:
Giuseppe Cappellano, Domizia Vecchio, Luca Magistrelli, Nausicaa Clemente, Davide Raineri, Camilla Barbero Mazzucca, Eleonora Virgilio, Umberto Dianzani, Annalisa Chiocchetti, Cristoforo Comi
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 6, Pp 1131-1137 (2021)
Osteopontin is a broadly expressed pleiotropic protein, and is attracting increased attention because of its role in the pathophysiology of several inflammatory, degenerative, autoimmune, and oncologic diseases. In fact, in the last decade, several s
Externí odkaz:
https://doaj.org/article/da8806555c8c4fabb90452e92c4647b3
Autor:
Chiara Monge, Ian Stoppa, Chiara Ferraris, Annalisa Bozza, Luigi Battaglia, Luigi Cangemi, Gianluca Miglio, Stefania Pizzimenti, Nausicaa Clemente, Casimiro Luca Gigliotti, Elena Boggio, Umberto Dianzani, Chiara Dianzani
Publikováno v:
Nanomaterials, Vol 12, Iss 23, p 4233 (2022)
High-grade melanoma remains a major life-threatening illness despite the improvement in therapeutic control that has been achieved by means of targeted therapies and immunotherapies in recent years. This work presents a preclinical-level test of a mu
Externí odkaz:
https://doaj.org/article/f1c2098e89e44523a47e692a13827ff3
Autor:
Romina Monzani, Mara Gagliardi, Nausicaa Clemente, Valentina Saverio, Elżbieta Pańczyszyn, Claudio Santoro, Nissan Yissachar, Annalisa Visciglia, Marco Pane, Angela Amoruso, Marco Corazzari
Publikováno v:
Biology, Vol 11, Iss 11, p 1574 (2022)
Background: IBD is a spectrum of pathologies characterized by dysregulated immune activation leading to uncontrolled response against the intestine, thus resulting in chronic gut inflammation and tissue damage. Due to its complexity, the molecular me
Externí odkaz:
https://doaj.org/article/4a15037f3ca0407c880f62e23aca5ef5