Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nausad Shaikh"'
Autor:
Ian R. Monk, Nausad Shaikh, Stephanie L. Begg, Mike Gajdiss, Liam K. R. Sharkey, Jean Y. H. Lee, Sacha J. Pidot, Torsten Seemann, Michael Kuiper, Brit Winnen, Rikki Hvorup, Brett M. Collins, Gabriele Bierbaum, Saumya R. Udagedara, Jacqueline R. Morey, Neha Pulyani, Benjamin P. Howden, Megan J. Maher, Christopher A. McDevitt, Glenn F. King, Timothy P. Stinear
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
WalKR is an essential two-component regulator that controls peptidoglycan synthesis in the human pathogen Staphylococcus aureus. Here, the authors provide biochemical, structural, and functional evidence supporting that the binding of a zinc ion inhi
Externí odkaz:
https://doaj.org/article/8c79c77e7e1c43c2b593eb5939e70c11
Autor:
Michael J. Kuiper, Ian R. Monk, Jean Y. H. Lee, Christopher A. McDevitt, Sacha J. Pidot, Rikki N. Hvorup, Saumya R. Udagedara, Neha Pulyani, Stephanie L. Begg, Benjamin P Howden, Torsten Seemann, Nausad Shaikh, Mike Gajdiss, Glenn F. King, Timothy P. Stinear, Gabriele Bierbaum, Brit Winnen, Jacqueline R. Morey, Brett M. Collins, Megan J. Maher, Liam K. R. Sharkey
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
WalKR (YycFG) is the only essential two-component regulator in the human pathogen Staphylococcus aureus. WalKR regulates peptidoglycan synthesis, but this function alone does not explain its essentiality. Here, to further understand WalKR function, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6268265ad24387b4c241cf0e17551f1
https://doi.org/10.1038/s41467-019-10932-4
https://doi.org/10.1038/s41467-019-10932-4
Autor:
Glenn F. King, Brit Winnen, Benjamin P Howden, Brett M. Collins, Christopher A. McDevitt, Timothy P. Stinear, Michael J. Kuiper, Ian R. Monk, Torsten Seemann, Mike Gajdiss, Jean Y. H. Lee, Nausad Shaikh, Stephanie L. Begg, Sacha J. Pidot, Rikki N. Hvorup, Gabriele Bierbaum
WalKR (YycFG) is the only essential two-component regulator in the human pathogenStaphylococcus aureus.WalKR regulates peptidoglycan synthesis, but this function alone appears not to explain its essentiality. To understand WalKR function we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9863994279360b3af7863626a0f7bb12
Publikováno v:
Molecular Pharmacology. 82:898-909
The human norepinephrine transporter (NET) is implicated in many neurological disorders and is a target of tricyclic antidepressants and nisoxetine (NX). We used molecular docking simulations to guide the identification of residues likely to affect s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a5fa0b0655e4890f9f723c8250c432
https://doi.org/10.1124/mol.112.080630
https://doi.org/10.1124/mol.112.080630