Membrane potential accelerates sugar uptake by stabilizing the outward facing conformation of the Na/glucose symporter vSGLT.

Autor: Khan F; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Structural Biology, Van Andel Institute, Grand Rapids, MI, 49503, USA., Elgeti M; Stein Eye Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA. melgeti@ucla.edu.; Institute for Drug Discovery, Leipzig University Medical School, Leipzig, Germany. melgeti@ucla.edu., Grandfield S; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, 11794, USA., Paz A; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Hauptman-Woodward Medical Research Institute, 700 Ellicott Street, Buffalo, NY, 14203, USA., Naughton FB; Department of Pharmaceutical Chemistry, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, 94158, USA., Marcoline FV; Department of Pharmaceutical Chemistry, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, 94158, USA., Althoff T; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Ermolova N; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Wright EM; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Hubbell WL; Stein Eye Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Grabe M; Department of Pharmaceutical Chemistry, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, 94158, USA. michael.grabe@ucsf.edu., Abramson J; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA. jabramson@mednet.ucla.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Nov 18; Vol. 14 (1), pp. 7511. Date of Electronic Publication: 2023 Nov 18.

The Role of C2 Domains in Two Different Phosphatases: PTEN and SHIP2.

Autor: John LH; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK., Naughton FB; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK., Sansom MSP; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK., Larsen AH; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.; Department of Neuroscience, University of Copenhagen, 2200 Copenhagen, Denmark.

Publikováno v: Membranes [Membranes (Basel)] 2023 Apr 04; Vol. 13 (4). Date of Electronic Publication: 2023 Apr 04.

Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes.

Autor: Yamamoto E; Department of System Design Engineering, Keio University, Yokohama, Kanagawa 223-8522, Japan., Domański J; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520, USA., Naughton FB; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.; Department of Physics, Arizona State University, Tempe, AZ 85287-1504, USA., Best RB; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520, USA., Kalli AC; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.; Leeds Institute of Cardiovascular and Metabolic Medicine and Astbury Center for Structural Molecular Biology, University of Leeds, Leeds, UK., Stansfeld PJ; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK., Sansom MSP; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

Publikováno v: Science advances [Sci Adv] 2020 Feb 19; Vol. 6 (8), pp. eaay5736. Date of Electronic Publication: 2020 Feb 19 (Print Publication: 2020).

Modes of Interaction of Pleckstrin Homology Domains with Membranes: Toward a Computational Biochemistry of Membrane Recognition.

Autor: Naughton FB; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom., Kalli AC; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom; Leeds Institute of Cancer and Pathology, St James' University Hospital, School of Medicine, University of Leeds, Leeds, United Kingdom., Sansom MSP; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom. Electronic address: mark.sansom@bioch.ox.ac.uk.

Publikováno v: Journal of molecular biology [J Mol Biol] 2018 Feb 02; Vol. 430 (3), pp. 372-388. Date of Electronic Publication: 2017 Dec 20.

Molecular dynamics simulations of human α-defensin 5 (HD5) crossing gram-negative bacterial membrane.

Autor: Awang, Tadsanee¹ (AUTHOR), Chairatana, Phoom² (AUTHOR) fsciprpo@ku.ac.th, Pongprayoon, Prapasiri^1,3 (AUTHOR) fsciprpo@ku.ac.th

Publikováno v: PLoS ONE. 11/21/2023, Vol. 18 Issue 11, p1-15. 15p.