Over-activation of iNKT cells aggravate lung injury in bronchopulmonary dysplasia mice.

Autor: Wang MY; Department of Pediatrics, The Affiliated Hospital of Jiangsu University, 438 Jiefang Road, Zhenjiang, 212001, China., Yi MX; Department of Pediatrics, The Affiliated Hospital of Jiangsu University, 438 Jiefang Road, Zhenjiang, 212001, China., Mo XY; Department of Pediatrics, The Affiliated Hospital of Jiangsu University, 438 Jiefang Road, Zhenjiang, 212001, China., Wei SJ; Department of Pediatrics, The Affiliated Hospital of Jiangsu University, 438 Jiefang Road, Zhenjiang, 212001, China., Qiao Y; Department of Pediatrics, The Affiliated Hospital of Jiangsu University, 438 Jiefang Road, Zhenjiang, 212001, China., Zhang Z; International Genome Center, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013, China., Su ZL; International Genome Center, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013, China; Institute for Medical Immunology, The Affiliated Hospital of Jiangsu University, 438 Jiefang Road, Zhenjiang, 212001, China. Electronic address: szl30@ujs.edu.cn., Lu HY; Department of Pediatrics, The Affiliated Hospital of Jiangsu University, 438 Jiefang Road, Zhenjiang, 212001, China. Electronic address: hylu@ujs.edu.cn.

Publikováno v: Redox biology [Redox Biol] 2024 Nov; Vol. 77, pp. 103370. Date of Electronic Publication: 2024 Sep 24.

Diverse NKT cells regulate early inflammation and neurological outcomes after cardiac arrest and resuscitation.

Autor: Tamura T; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan., Cheng C; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.; Stem Cell Biology Program, Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, USA., Villaseñor-Altamirano AB; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Yamada K; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Ikeda K; Harvard Medical School, Boston, MA 02115, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Hayashida K; Harvard Medical School, Boston, MA 02115, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Menon JA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Chen XD; Broad Institute of MIT and Harvard, Cambridge, MA 02138, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA., Chung H; Broad Institute of MIT and Harvard, Cambridge, MA 02138, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA., Varon J; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Chen J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Choi J; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Cullen AM; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Guo J; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Lin X; Harvard Medical School, Boston, MA 02115, USA.; Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02142, USA., Olenchock BA; Harvard Medical School, Boston, MA 02115, USA.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Pinilla-Vera MA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Manandhar R; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Sheikh MDA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Hou PC; Harvard Medical School, Boston, MA 02115, USA.; Division of Emergency and Critical Care Medicine, Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Lawler PR; McGill University Health Centre, Montreal, Quebec H3A 2B4, Canada.; University of Toronto, Toronto, Ontario M5R 0A3, Canada., Oldham WM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Seethala RR; Harvard Medical School, Boston, MA 02115, USA.; Division of Emergency and Critical Care Medicine, Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Baron RM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Bohula EA; Harvard Medical School, Boston, MA 02115, USA.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Morrow DA; Harvard Medical School, Boston, MA 02115, USA.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Blumberg RS; Harvard Medical School, Boston, MA 02115, USA.; Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02142, USA., Chen F; Broad Institute of MIT and Harvard, Cambridge, MA 02138, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA., Merriam LT; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Weissman AJ; Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Brenner MB; Harvard Medical School, Boston, MA 02115, USA.; Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Chen X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Ichinose F; Harvard Medical School, Boston, MA 02115, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Kim EY; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 Dec 04; Vol. 16 (776), pp. eadq5796. Date of Electronic Publication: 2024 Dec 04.

Lipid accumulation in adipose tissue-resident iNKT cells contributes to an inflammatory phenotype.

Autor: Morris I; Ce nter for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Vrieling F; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands., Bouwman A; Ce nter for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Stienstra R; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., Kalkhoven E; Ce nter for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Adipocyte [Adipocyte] 2024 Dec; Vol. 13 (1), pp. 2421750. Date of Electronic Publication: 2024 Nov 01.

State of play in the molecular presentation and recognition of anti-tumor lipid-based analogues.

Autor: Praveena T; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Le Nours J; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Nov 28; Vol. 15, pp. 1479382. Date of Electronic Publication: 2024 Nov 28 (Print Publication: 2024).

Identification of Functional Immune Biomarkers in Breast Cancer Patients.

Autor: Derakhshandeh R; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Zhu Y; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Li J; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Hester D; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Younis R; Department of Oncology and Diagnostic Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Baltimore, MD 21201, USA., Koka R; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Baltimore, MD 21201, USA.; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Jones LP; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Baltimore, MD 21201, USA.; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Sun W; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Goloubeva O; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Baltimore, MD 21201, USA.; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Tkaczuk K; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Baltimore, MD 21201, USA., Bates J; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Reader J; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Baltimore, MD 21201, USA.; Department of Pharmaceutical Sciences, University of Maryland Eastern Shore, Princess Anne, MD 21853, USA.; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Webb TJ; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Baltimore, MD 21201, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 16; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 16.