Zobrazeno 1 - 10
of 1 084
pro vyhledávání: '"Natural killer (NK) cells"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract The serine/threonine/tyrosine kinase 1 (STYK1) is a receptor protein-tyrosine kinase (RPTK)-like molecule that is detected in several human organs. STYK1 plays an important role in promoting tumorigenesis and metastasis in various cancers. B
Externí odkaz:
https://doaj.org/article/dc5503756b1941199e25a65e1aab4472
Autor:
Yuanning Du, Samuel Metcalfe, Shreya Akunapuram, Sugata Ghosh, Charles Spruck, Angela M. Richardson, Aaron A. Cohen‐Gadol, Jia Shen
Publikováno v:
FEBS Open Bio, Vol 14, Iss 6, Pp 1028-1034 (2024)
Glioblastoma (GBM) poses a significant challenge in oncology and stands as the most aggressive form of brain cancer. A primary contributor to its relentless nature is the stem‐like cancer cells, called glioblastoma stem cells (GSCs). GSCs have the
Externí odkaz:
https://doaj.org/article/ad678e993aca4fd191290cbd97a38ead
Autor:
Ralph J. A. Maas, Janneke S. Hoogstad-van Evert, Iris M. Hagemans, Jolanda Brummelman, Diede van Ens, Paul K. J. D. de Jonge, Laura Hooijmaijers, Shweta Mahajan, Anniek B. van der Waart, Charlotte K. J. C. Hermans, Janne de Klein, Rob Woestenenk, Antonius E. van Herwaarden, Nicolaas P. M. Schaap, Somayeh Rezaeifard, Daniele V. F. Tauriello, Petra L. M. Zusterzeel, Nelleke Ottevanger, Joop H. Jansen, Willemijn Hobo, Harry Dolstra
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Natural killer (NK) cell therapy represents an attractive immunotherapy approach against recurrent epithelial ovarian cancer (EOC), as EOC is sensitive to NK cell-mediated cytotoxicity. However, NK cell antitumor activity is dampened by suppressive f
Externí odkaz:
https://doaj.org/article/fba2485f4f604077a2047c69ad71b92f
Autor:
Mohamed A Selim, Reda A. Suef, Ebrahim Saied, Mostafa A. Abdel-Maksoud, Saeedah Musaed Almutairi, Mohammed Aufy, Adel A. Mousa, Mohamed T. M. Mansour, Mohamed M. S. Farag
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe relationship between chronic hepatitis B (CHB) infection and natural killer (NK) cell dysfunction is well-established, but the specific role of HBV viral antigens in driving NK cell impairment in patients with CHB remains unclear. This
Externí odkaz:
https://doaj.org/article/1e6a6c9e51824783b44f684359d89dbe
Autor:
Leisheng Zhang, Yunyan Sun, Chun-e Xue, Shuling Wang, Xianghong Xu, Chengyun Zheng, Cunrong Chen, Dexiao Kong
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Acute myeloid leukemia (AML) is a highly heterogeneous hematologic malignancy and the most frequently acute leukemia of stem cell precursors and the myeloid derivatives in adult. Longitudinal studies have indicated the therapeutic
Externí odkaz:
https://doaj.org/article/f48558806bd84eeea7cb33c5b23fdfdb
Autor:
Frederic St‐Denis‐Bissonnette, Shirley Qiu, Sarah E. Cummings, Melanie Kirkby, Yohannes Haile, Sarah Wassmer, Gauri Muradia, Jelica Mehic, Andrew Stalker, Amit Shrestha, Michele Ardolino, Seung‐Hwan Lee, Dylan Burger, Lisheng Wang, Jessie R. Lavoie
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 7, Pp n/a-n/a (2024)
Abstract Natural killer cell‐derived extracellular vesicles (NK‐EVs) are candidate biotherapeutics against various cancers. However, standardised potency assays are necessary for a reliable assessment of NK‐EVs' cytotoxicity. This study aims to
Externí odkaz:
https://doaj.org/article/e9c74a4ae6444282ad687844f70ffab3
Autor:
Azadeh Rahimi, Zahra Malakoutikhah, Ilnaz Rahimmanesh, Gordon A. Ferns, Reza Nedaeinia, Sayed Mohammad Matin Ishaghi, Nasim Dana, Shaghayegh Haghjooy Javanmard
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract The metastasis of melanoma cells to regional lymph nodes and distant sites is an important contributor to cancer-related morbidity and mortality among patients with melanoma. This intricate process entails dynamic interactions involving tumo
Externí odkaz:
https://doaj.org/article/3fc45d2470474b989249730ff7fd7b9d
Publikováno v:
Cells, Vol 13, Iss 18, p 1567 (2024)
Glioblastoma multiforme (GBM) is the most common type of primary malignant brain tumor and has a dismal overall survival rate. To date, no GBM therapy has yielded successful results in survival for patients beyond baseline surgical resection, radiati
Externí odkaz:
https://doaj.org/article/68725c6ba0cf4331802824acc35661fe
Autor:
Reza Darvishvand, Somayeh Rezaeifard, Razie Kiani, Sedigheh Tahmasebi, Zahra Faghih, Nasrollah Erfani
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Background Natural killer (NK) cells, CD3− lymphocytes, are critical players in cancer immune surveillance. This study aimed to assess two types of CD3− NK cell classifications (subsets), that is, convectional subsets (based on CD56 and
Externí odkaz:
https://doaj.org/article/5a617e0d074d4e16b06f5b796c9f92ac
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Natural killer (NK) cells hold great promise in treating diverse hematopoietic and solid tumors. Despite their availability from peripheral blood and cord blood, stem cell-derived NK cells offer an 'off-the-shelf' solution. Hemato
Externí odkaz:
https://doaj.org/article/447de0e7b36f4117b5a463443db1dadc