Výsledky vyhledávání - "Natsumi Susai"

Akademický článek

Analysis of real-world data and a mouse model indicates that pirfenidone causes pellagra

Autor: Koji Kuronuma, Natsumi Susai, Tomohiro Kuroita, Hiroki Yamamoto, Takeshi Yoshioka, Shuji Kaneko, Hirofumi Chiba

Publikováno v: ERJ Open Research, Vol 8, Iss 4 (2022)

Background Pirfenidone (PFD) is widely used in patients with idiopathic pulmonary fibrosis (IPF) and its adverse effects, such as nausea and photosensitivity, are well known. Many patients with IPF have reduced doses or even cessation of PFD because

Externí odkaz: https://doaj.org/article/c99280ed6396454ba257778d6bf569c9

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Protective effect of Bifidobacterium longum BB536 against nausea caused by pirfenidone in a mouse model of pellagra

Autor: Koji KURONUMA, Natsumi SUSAI, Tomohiro KUROITA, Takeshi YOSHIOKA, Atsushi SAITO, Hirofumi CHIBA

Publikováno v: Bioscience of Microbiota, Food and Health.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9cd8ee1595a85a72594af2804c333fe
https://doi.org/10.12938/bmfh.2022-042

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Effect of niacin supplementation on nausea-like behaviour in an isoniazid-induced mouse model of pellagra

Autor: Natsumi Susai, Takeshi Yoshioka, Tatsuru Ishikawa, Tomohiro Kuroita, Koji Kuronuma

Publikováno v: British Journal of Nutrition. 127:961-971

Niacin deficiency causes pellagra, the symptoms of which include dermatitis, diarrhoea and dementia. Investigating the mechanism underlying these phenotypes has been challenging due to the lack of an appropriate animal model. Here, we report a mouse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49875d3c5866fabea733ad5a60b3f164
https://doi.org/10.1017/s0007114521001835

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Analysis of the gut microbiome to validate a mouse model of pellagra

Autor: Natsumi SUSAI, Tomohiro KUROITA, Koji KURONUMA, Takeshi YOSHIOKA

Publikováno v: Bioscience of microbiota, food and health. 41(2)

Pellagra is caused by an abnormal intake and/or use of niacin, but its phenotypes are diverse. The phenotypes of pellagra can also be atypical, such as nausea. We previously reported a mouse model of pellagra-related nausea. However, the mechanism of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce1f59a0e04b4ad902dc7bce6048733
https://pubmed.ncbi.nlm.nih.gov/35433165

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