Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Natsumi Ohkura"'
Publikováno v:
Pharmacology & Pharmacy. :329-340
Inhibition of protein tyrosine phosphatase by orthovanadate induces vasoconstriction, which is mediated by the Rho kinase-dependent inactivation of myosin light chain phosphatase (MLCP) via signaling downstream of Src-induced activation of the epider
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::239076f59b9d278f63286133abe99ed0
https://doi.org/10.4236/pp.2015.67035
https://doi.org/10.4236/pp.2015.67035
Publikováno v:
European journal of pharmacology. 762
We previously found that the protein tyrosine phosphatase inhibitor orthovanadate evoked a vasoconstrictor effect in rat aortas via Rho-kinase-dependent inactivation of myosin light chain phosphatase (MLCP) downstream of epidermal growth factor (EGF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8f2ba4f47349e3b9b6a1255b5b453e
https://pubmed.ncbi.nlm.nih.gov/26004531
https://pubmed.ncbi.nlm.nih.gov/26004531
Autor:
Natsumi Ohkura, Asami Kobe, Tomoya Sasahara, Hiroshi Okamoto, Katsutoshi Yayama, Hisaaki Ohba
Publikováno v:
Hypertension. 64
Orthovanadate (OVA), a protein tyrosine phosphatase (PTPase) inhibitor, exerts contractile effects on smooth muscle in a Rho-kinase-dependent manner, but the precise mechanisms are not elucidated. The aim of this study was to determine the potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe88305411bcc05e6c7f0deb3cd8f32b
https://doi.org/10.1161/hyp.64.suppl_1.mp06
https://doi.org/10.1161/hyp.64.suppl_1.mp06